Possible Hemolytic Uremic Syndrome in Three Cats After Renal Transplantation and Cyclosporine Therapy     

Lillian R. Aronson  VMD  Diplomate ACVS    Clare Gregory  DVM  Diplomate ACVS 《Veterinary surgery : VS》1999,28(3):135-140

OBJECTIVE: To describe the clinical history of 3 cats with possible hemolytic uremic syndrome (HUS) after renal transplantation. STUDY DESIGN: This case series documents historical findings, physical examination findings, clinical pathologic features, necropsy and histopathologic findings of 3 cats with possible HUS. RESULTS: Two cats had chronic renal failure; 1 cat had acute renal failure secondary to ethylene glycol toxicity. A renal transplant was performed in each of the 3 cats without obvious problems. Complications that would support a diagnosis of HUS, including anemia, thrombocytopenia, and azotemia occurred within 24 hours in 1 cat, within 8 days in a second cat, and 2 months after transplantation in the third cat. In 2 cats, HUS was likely secondary to cyclosporine immunosuppression. In the third cat, HUS may have been secondary to allograft rejection. Renal biopsies from all 3 cats were suggestive of HUS. CONCLUSION AND CLINICAL RELEVANCE: In human beings, HUS in transplant recipients may occur secondary to immunosuppressive drugs, vascular rejection, or recurrence of original disease. Graft loss occurred in all 3 cats in this study and the mortality rate was 100%. Clinicians caring for these patients need to be aware of this disorder because early recognition and treatment is critical in the management of post-transplant HUS.  相似文献   

RADIOGRAPHIC MEASUREMENT OF CARDIAC SIZE IN NORMAL FERRETS     

Rebecca L.  Stepien  DVM  MS  Keith G.  Benson  DVM  Lisa J.  Forrest  VMD 《Veterinary radiology & ultrasound》1999,40(6):606-610

Right lateral, left lateral and ventrodorsal radiographs were obtained in 20 normal ferrets (11 male). Three independent observers recorded measurements of the cardiac silhouette and results for each parameter were averaged. Long axis (length), short axis (width) and total of length plus width (L+W) were recorded in each view. Comparative measurements were calculated, including the ratio of L+W/length of thoracic vertebrae 5-8, and a modified vertebral heart score (VHS) method, measuring the heart in vertebral units. Measurements made in ventrodorsal views were usually larger than corresponding measurements in lateral views. Weight and most absolute measurements differed significantly between male and female ferret (P<0.05), but the differences in absolute measurements were not apparent when related to measures of body size (Ratio and modified VHS methods). Given the variability in body weight and size in ferrets, measurements of the cardiac silhouette normalized for body size may be more universally applicable than absolute measurements.  相似文献   

Feeding the rapidly growing foal     

Sarah L. Ralston VMD  PhD 《Journal of Equine Veterinary Science》1997,17(12):634-636

Young, rapidly growing foals can be fed rations that sustain good growth rates, as long as the proper mineral balance is included. Rations causing significant postprandial hyperglycemia/hyperinsulinemia, such as sweet feeds, should be avoided if the foal is from a bloodline known to be predisposed to osteochondritis dissecans (OCD). Protein intake should not be less than 14% dry matter intake in the first year of life in order to promote optimal growth rates and development. Calcium, phosphorus, copper, and zinc intakes should also be increased in the first 2 years of life.  相似文献