The glucocorticoid sparing efficacy of Phytopica^TM in the management of canine atopic dermatitis     

Vanessa Schmidt  Neil McEwan  rea Volk  John Helps  Kevin Morrell  Tim Nuttall 《Veterinary dermatology》2010,21(1):97-105

This double-blind randomized placebo-controlled trial indicates that Phytopica™ can be an effective glucocorticoid sparing agent in canine atopic dermatitis (AD). Twenty-two dogs with perennial AD [Canine Atopic Dermatitis with Severity Index (CADESI-03) ≥ 60] were given 200 mg/kg Phytopica™ or an identical placebo in food once daily for 56 days. All dogs were initially given 0.4 mg/kg methyl-prednisolone once daily, which was then adjusted according to the daily pruritus score (0–100 mm visual analogue scale). The cumulative dose and pruritus score were lower in the Phytopica™ than the placebo group. There were statistically significant time and treatment effects for the methyl-prednisolone dose and pruritus score, but there were no significant differences between the Phytopica™ and placebo groups in the proportion of dogs that achieved a > 50% reduction in dose or pruritus scores at day 56; the mean CADESI-03 scores at days 0, 28 and 56; the numbers achieving >50% reduction in CADESI-03 at days 28 and 56; or in the owners' global efficacy score at days 28 and 56. Adverse events included diarrhoea (three Phytopica™ and one placebo treated dog), polyuria/polydipsia (three dogs in each group), and polyphagia, intermittent anorexia and panting (one dog each in the placebo group). None of these by themselves required withdrawal of treatment.  相似文献   

Potato production in Florida as influenced by soil acidity and nitrogen sources     

G. M. Volk  Nathan Gammon 《American Journal of Potato Research》1954,31(3):83-92

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Influence of head positioning on the assessment of Chiari-like malformation in Cavalier King Charles spaniels     

Upchurch JJ  McGonnell IM  Driver CJ  Butler L  Volk HA 《The Veterinary record》2011,169(11):277

Chiari-like malformation (CM) is almost omnipresent in the Cavalier King Charles spaniels (CKCS), often leading to syringomyelia (SM). Morphometric studies have produced variable results concerning relationship between the brain parenchyma within the caudal cranial fossa (CCF) and SM. The present study assesses the effect of head position, one potential confounder. Magnetic resonance images of CKCS with CM were reviewed in extended and flexed head positions. Volumes were calculated from transverse T2-weighted brain images. Mid-sagittal images were used for measurement of cerebellar herniation and CSF space between cerebellum and brainstem. Fourteen CKCS were included into the study, seven dogs with CM and seven with CM/SM. There was no difference between the relative brain parenchyma within the CCF in extended position and flexed position, or the brain parenchyma within the rostral and middle cranial fossae proportion. Cerebellar herniation and CSF space between cerebellum and brainstem were significantly increased in the flexed position. Cerebellar herniation and CSF space differed significantly between CM and CM/SM in a flexed head position. Volumetric measurements did not vary with head position. Cerebellar herniation and CSF space between the cerebellum and the brainstem were larger in a flexed head position.  相似文献   

Seizures in dogs under primary veterinary care in the United Kingdom: Etiology,diagnostic testing,and clinical management     

Alexander Erlen  Heidrun Potschka  Holger A. Volk  Carola Sauter-Louis  Dan G. O'Neill 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2020,34(6):2525-2535

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Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management     

Sinziana Maria Radulescu  Karen Humm  Louis Mark Eramanis  Holger A. Volk  David B. Church  David Brodbelt  Dan Gerard O'Neill 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2020,34(5):1993-2004

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A multicenter randomized controlled trial of medium-chain triglyceride dietary supplementation on epilepsy in dogs     

Benjamin A. Berk  Tsz H. Law  Rowena M. A. Packer  Annette Wessmann  Andrea Bathen-Nöthen  Tarja S. Jokinen  Anna Knebel  Andrea Tipold  Ludovic Pelligand  Zoe Meads  Holger A. Volk 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2020,34(3):1248-1259

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Orientierende Untersuchungen über den Einfluβ der Fruchtfolge auf die Vermehrung von Erbsenschädlingender Fruchtfolge auf die Vermehrung von Erbsenschädlingen     

St. Volk  S. Bombosch 《Journal of pest science》1968,41(4):57-63

Diskussion und Zusammenfassung Die Untersuchungsergebnisse zeigen sehr unterschiedliche Auswirkungen des Daueranbaues der Erbsen auf die an ihnen lebenden Schälinge.S. lineata vermehrt sich auf im Daueranbau befindlichen Erbsenparzellen stets schlechter als auf den erstmalig mit dieser Fruch bestellten. Die Populationsdichte von Thysanopteren ist weitgehend unabhä ngig von der Dauer des Erbsenanbaues, wobei sehr auffallend ist, daß es trotz einer mit steigender Anbaudauer zunehmenden Verringerung der Pflanzensubstanz zu keiner Zunahme der Thripsschäden kommt. Lediglich beiC. pisi steigt die Larvendichte mit der Anbaudauer ihrer Wirtspflanze, aber auch bei dieser Art war auf der Parzelle mit dem längsten Erbsenanbau ebenfalls ein Rückgang der Dichte festzustellen. Über die Ursachen der unterschiedlichen Auswirkungen können vorerst keine Aussagen gemacht werden. Als Ansatzpunkte zu einer Klä rung könnten beiS. lineata die Beziehungen zwischen Larvenentwicklung und Knöllchenbesatz unter Berücksichtigung des Auftretens von Mykosen an diesem Schädling, bei Thysanopteren die Aufklärung des Artenspektrums insbesondere bezüglich des Vorkommens räuberischer Arten und beiC. pisi eine genaue Untersuchung der Verhältnisse auf Flächen mit sehr langem Erbsenanbau dienen. Unabhängig von de Lü cken in unseren Kenntnissen über die Ursachen der ermittelten Tatbestände bleibt die Feststellung, daß auch im Erbsenanbau Fruchfolgefehler keineswegs grundsätzlich zu Massenvermehrungen der an dieser Kulturpflanze lebenden phystophagen Insekten führen, oder anders ausgedrückt, die Fruchtfolge auch bei Erbsen nicht unbedingt als eine Methode zur Unterdrückung von Massenvermehrungen schädlicher Insekten angesehen werden kann. nt[mis|Herrn Prof. Dipl.-Ing. Dr. E. Schimitschek zum 70. Geburtstag gewidmet.Der Deutschen Forschungsgemeinschaft danken wir für die Unterstützung der Arbeiten, der Fa. van. Waveren für die kostenlose Überlassung des Saatgutes.  相似文献   

Gewohnheiten beim Waldbesuch     

H. Volk 《European Journal of Forest Research》1978,97(1):192-208

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Portosystemic shunt associated with severe episodic weakness     

Wessmann A  Volk HA  Shelton GD  Chandler KE  Baines S  Cappello R 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2006,20(4):1042-1044

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MRI features of CNS lymphoma in dogs and cats     

Palus V  Volk HA  Lamb CR  Targett MP  Cherubini GB 《Veterinary radiology & ultrasound》2012,53(1):44-49

The magnetic resonance (MR) imaging features of central nervous system lymphoma in eight dogs and four cats are described. Intracranial lesions affected the rostrotentorial structures in six dogs and caudotentorial structures in two cats. Lesions affected the spinal cord in two dogs and in two cats. One dog and one cat with intracranial lymphoma had signs of local extracranial extension and lymphadenopathy. Lesions were considered extraparenchymal in four dogs and three cats, intraparenchymal in two dogs and one cat, and appeared to have both intra- and extraparenchymal components in two dogs. All lesions were hyperintense in T2-weighted images when compared to white matter, most were hypointense in T1-weighted images (7/12), and most were hyperintense in fluid-attenuated inversion recovery (FLAIR) images (5/9). When compared to grey matter, these lesions appear either isointense (5/12) or hyperintense (7/12) on T2-weighted images, half of them were hypointense in T1-weighted images (6/12), and most were isointense in FLAIR images (7/9). Lesion margins were usually indistinct in T2-weighted images (10/12) and had perilesional hyperintensity in FLAIR images (7/9). The majority of lesions (10/12) had abnormal meninges around the lesion and half (6/12) had generalized contrast enhancement. Mass effect was evident in all lesions. Although not specific, when combined with the history and neurologic signs, MR features aid presumptive diagnosis that should be confirmed by cytology or histopathology.  相似文献