Proctitis associated with chlamydial infection in a koala     

S HEMSLEY  PJ CANFIELD 《Australian veterinary journal》1996,74(2):148-150

Objective To describe proctitis associated with chlamydial infection in a koala.
Design A pathological study  

Animal

A free living, male koala aged 17 years.
Procedure Rectum was examined histologically and chlamydial organisms visualised using Giminez stain and an immunoperoxidase staining method using an anti- Chlamydia lipopolysaccharide (genus specific) antibody.
Results An aged koala presented for euthanasia was found to have asymptomatic chronic proctitis, cystitis, prostatitis, urethritis and conjunctivitis associated with chlamydial infection. Inflammation was severe in the terminal rectum and extended into the proximal common vestibule. Chlamydial organisms were visualised in the rectal surface epithelium using Giminez stain and an immunoperoxidase staining method. Organisms were also detected in the epithelium of the bladder, prostate and urethra.  

Clinical Implications

Possible modes of transmission for the rectal infection are direct sexual transmission or ascending infection by organisms shed from the urogenital tract into the common vestibule. Previously unreported chlamydial proctitis in the koala may represent a potential reservoir of infection for other koalas.  相似文献   

Urinalysis in captive koalas     

PJ. CANFIELD  DR. GEE  DI. WIGNEY 《Australian veterinary journal》1989,66(11):376-377

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The natural regulation of Trichostrongylus spp. populations in young grazing sheep     

Peter J. Waller  Robert J. Thomas 《Veterinary parasitology》1981,9(1):47-55

The dynamics of Trichostrongylus axei and intestinal Trichostrongylus spp. were studied in grazing lambs over a 2-year period. Monthly comparisons were made between worm counts of experimental lambs continuously exposed to infection from 3 to 7 months of age, and tracer lambs which were allowed to graze on the experimental plots for successive 4-week periods.It was found that irrespective of the level of larval intake, experimental lambs were unable to regulate their worm burdens until at least 5 months of age. When larval intake was high, resistance to establishment of larvae apparently occurred at approximately 6 months of age followed by rejection and resistance to reinfection. In conditions of low larval intake, worms accumulated with no apparent control operating in lambs up to 7 months of age.These results suggest that a rapid turnover of worm populations does not occur in Trichostrongylus spp., and that in young lambs, worms accumulate until sufficient exposure to infection stimulates resistance to larval establishment and ultimately rejection of adults.  相似文献   

Renal complications of cystitis in koalas     

PJ CANFIELD  AJ SPENCER 《Australian veterinary journal》1993,70(8):310-311

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The effect of ageing on the antigenicity of Haemonchus contortus larvae.     

R J Thomas  P J Waller  B R Cottrill 《Research in veterinary science》1975,19(1):113-114

Viable Haemonchus contortus larvae used as a source of antigen in complement fixation tests showed a decrease in antigenic potency following storage for approximately two months at 5 degrees C. In contrast, larvae killed by freezing and stored at --15 degree C showed no such decline over a similar period. It is suggested that this loss of potency with ageing may be partly responsible for increased worm populations in sheep in spring.  相似文献   

Effects of hydromorphone or oxymorphone, with or without acepromazine, on preanesthetic sedation, physiologic values, and histamine release in dogs     

Smith LJ  Yu JK  Bjorling DE  Waller K 《Journal of the American Veterinary Medical Association》2001,218(7):1101-1105

OBJECTIVE: To compare hydromorphone with oxymorphone, with or without acepromazine, for preanesthetic sedation in dogs and assess changes in plasma concentration of histamine after drug administration. DESIGN: Randomized clinical study. ANIMALS: 10 healthy mixed-breed dogs. PROCEDURE: Dogs were treated IM with hydromorphone (group H), oxymorphone (group O), hydromorphone with acepromazine (group H/A), or oxymorphone with acepromazine (group O/A). Sedation score, heart rate, respiratory rate, systolic blood pressure, and oxygen saturation were recorded at baseline immediately after drug administration (T0) and every 5 minutes for 25 minutes (T25). Plasma histamine concentration was measured at baseline and T25. RESULTS: Sedation was similar between groups H and 0 at all times. Sedation was significantly greater for groups H/A and O/A from T10 to T25, compared with other groups. Systolic blood pressure was significantly reduced at T25 in group H/A, compared with group H, and in group O/A, compared with group O. Prevalence of panting at T25 was 50% for groups H and O, compared with 20% for group H/A and 30% for group O/A. By T25, heart rate was significantly lower in all groups. Oxygen saturation was unaffected by treatment. Mean +/- SD plasma histamine concentration was 1.72 +/- 2.69 ng/ml at baseline and 1.13 +/- 1.18 ng/ml at T25. There was no significant change in plasma histamine concentration in any group. CONCLUSIONS AND CLINICAL RELEVANCE: Hydromorphone is comparable to oxymorphone for preanesthetic sedation in dogs. Sedation is enhanced by acepromazine. Neither hydromorphone nor oxymorphone caused an increase in plasma histamine concentration.  相似文献   

Chromosomal locations of human tissue plasminogen activator and urokinase genes   总被引：7，自引：0，他引：7  

B Rajput  S F Degen  E Reich  E K Waller  J Axelrod  R L Eddy  T B Shows 《Science (New York, N.Y.)》1985,230(4726):672-674

A panel of human-mouse somatic cell hybrids and specific complementary DNA probes were used to map the human tissue plasminogen activator and urokinase genes to human chromosomes 8 and 10, respectively. This result is in contrast to a previous assignment of a plasminogen activator gene to chromosome 6. As neoplastic cells produce high levels of plasminogen activator, it is of interest that aberrations of chromosome 8 have been linked to various leukemias and lymphomas and that two human oncogenes, c-mos and c-myc, have also been mapped to chromosome 8.  相似文献   

Niobium/Uranium Evidence for Early Formation of the Continental Crust   总被引：1，自引：0，他引：1  

PJ Sylvester  IH Campbell  DA Bowyer 《Science (New York, N.Y.)》1997,275(5299):521-523

Niobium/uranium ratios in greenstone-belt basalts and gabbros indicate that parts of the Late Archean mantle beneath Western Australia underwent a level of melt extraction, resulting in formation of the continental crust, comparable to that seen in the present mantle. The implication is either that (i) the amount of continental crust that formed before 2.7 x 10(9) years ago was much greater than generally thought or (ii) crustal growth occurred by severe depletion of small volumes of the mantle rather than by moderate depletion of a large volume of mantle.  相似文献   

Remaining vigilant for the exotic: cases of imported canine leishmaniosis in Australia 2000–2011     

E Cleare  K Mason  J Mills  M Gabor  PJ Irwin 《Australian veterinary journal》2014,92(4):119-127

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Use of REP‐PCR and 16S rRNA gene sequencing for comparison of Mannheimia haemolytica isolates obtained from fatal cases of bovine respiratory disease in the USA and Australia     

JD Taylor  DJ Doyle  PJ Blackall  AW Confer 《Australian veterinary journal》2014,92(1-2):15-23

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