Using Syndromic Surveillance to Estimate Baseline Rates for Healthcare‐Associated Infections in Critical Care Units of Small Animal Referral Hospitals     

A. Ruple‐Czerniak  H.W. Aceto  J.B. Bender  M.R. Paradis  S.P. Shaw  D.C. Van Metre  J.S. Weese  D.A. Wilson  J.H. Wilson  P.S. Morley 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2013,27(6):1392-1399

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Effect of Embryonic and Maternal Genotype on Embryo and Foetal Survival in Rabbit     

JS Vicente  MD Llobat  E Jiménez‐Trigos  R Lavara  F Marco‐Jiménez 《Reproduction in domestic animals》2013,48(3):402-406

The aim of this work was to study the influence of embryonic and maternal genotype of two lines of rabbits selected by growth rate (line R) and litter size at weaning (line A) on prenatal survival. Embryos were recovered at 48 h of gestation from R and A donors (39 and 35 does, respectively) and reciprocally transferred to the oviducts of recipient does to the R (n = 15) and A (n = 14) lines. Each recipient doe received six embryos from line R into one oviduct and six embryos from line A into the other. Recipient does were examined by laparoscopy to determine implantation rate on day 14 and slaughtered on day 25 of gestation to determine the number of live foetuses and the weight of foetuses and placentas. No differences were found between lines in fertilization rate and stage of embryo development at 48 h post‐insemination. Implantation rate was affected by both the embryonic and maternal genotype. While embryos from donor line A had the highest implantation rate (0.78 ± 0.032 vs 0.65 ± 0.036 for line R), recipient line R had a better implantation rate (0.78 ± 0.033 vs 0.64 ± 0.036 for line A). Foetal survival was affected by the embryonic genotype. Embryos from donor line A had a higher foetal survival rate than embryos from donor line R (0.65 ± 0.036 vs 0.53 ± 0.038, respectively) but lower foetal and placenta weights. In conclusion, while embryonic genotype influenced both implantation and foetal survival rate, R embryos had the lowest rates, maternal genotype affected the implantation rate and R recipients may show a greater uterine receptivity during implantation period. Moreover, it must be observed that foetal and placenta weights were significantly affected by embryonic genotype and heavier for R line.  相似文献   

The canine and feline skin microbiome in health and disease     

J. Scott Weese 《Veterinary dermatology》2013,24(1):137-e31

The skin harbours a diverse and abundant, yet inadequately investigated, microbial population. The population is believed to play an important role in both the pathophysiology and the prevention of disease, through a variety of poorly explored mechanisms. Early studies of the skin microbiota in dogs and cats reported a minimally diverse microbial composition of low overall abundance, most probably as a reflection of the limitations of testing methodology. Despite these limitations, it was clear that the bacterial population of the skin plays an important role in disease and in changes in response to both infectious and noninfectious diseases. Recent advances in technology are challenging some previous assumptions about the canine and feline skin microbiota and, with preliminary application of next‐generation sequenced‐based methods, it is apparent that the diversity and complexity of the canine skin microbiome has been greatly underestimated. A better understanding of this complex microbial population is critical for elucidation of the pathophysiology of various dermatological (and perhaps systemic) diseases and to develop novel ways to manipulate this microbial population to prevent or treat disease.  相似文献   

Evaluation of biofilm production by Pseudomonas aeruginosa from canine ears and the impact of biofilm on antimicrobial susceptibility in vitro     

Charlotte C. Pye  Anthony A. Yu  J. Scott Weese 《Veterinary dermatology》2013,24(4):446-e99

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Assessment of the Fecal Microbiota in Beef Calves          下载免费PDF全文

J.S. Weese  M. Jelinski 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2017,31(1):176-185

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Bilateral oblique facial clefts,rudimentary eyes and hydrocephalus in an aborted equine foetus          下载免费PDF全文

JS Agerholm  HG Pedersen  FJ McEvoy  S Heegaard 《Reproduction in domestic animals》2017,52(4):692-695

Knowledge of congenital malformations and their causes in horses is generally sparse. Such conditions require more scientific attention to improve their diagnostics and inform prevention strategies. Here, a unique syndrome of bilateral oblique facial clefts (meloschisis), rudimentary eyes and hydrocephalus is reported in an equine foetus spontaneously aborted at gestation day 224. The cause of abortion was considered to be intrauterine death caused by umbilical cord torsions and subsequent compromised blood flow, but the aetiology of the malformation could not be determined. A detailed history, which includes exposure to a range of pharmaceutical compounds during the early stages of pregnancy, is provided and emphasizes the need for accurate recording of treatments in pregnant animals.  相似文献   

Relationship between sources of pet acquisition and euthanasia of cats and dogs in an animal shelter: a pilot study          下载免费PDF全文

AI Arbe Montoya  JS Rand  RM Greer  C Alberthsen  D Vankan 《Australian veterinary journal》2017,95(6):194-200

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In vitro miconazole susceptibility of meticillin-resistant Staphylococcus pseudintermedius and Staphylococcus aureus     

JS Weese  M Walker  T Lowe 《Veterinary dermatology》2012,23(5):400-e74

Background – The emergence and dissemination of meticillin‐resistant staphylococci has created significant treatment challenges in veterinary medicine and increased interest in topical therapy for superficial infections. Concern has been expressed regarding the use of some topical antimicrobials in animals because of the potential for emergence of resistance, and additional options are required. Miconazole has limited antibacterial properties that include antistaphylococcal activity. Hypothesis/Objectives – The objective of this study was to assess the in vitro susceptibility of Staphylococcus pseudintermedius and Staphylococcus aureus to miconazole. Methods – In vitro susceptibility of 112 meticillin‐resistant S. pseudintermedius (MRSP), 53 meticillin‐resistant S. aureus (MRSA) and 37 meticillin‐susceptible S. pseudintermedius (MSSP) to miconazole was assessed using agar dilution. Results – The minimal inhibitory concentration (MIC) range, MIC₅₀ and MIC₉₀ for MRSP were 1–8, 2 and 4 μg/mL, respectively. Corresponding results for MRSA were 1–8, 2 and 6 μg/mL, and for MSSP 1–4, 2 and 2 μg/mL. The MIC for MSSP was a significantly lower MIC than that for both MRSP (P = 0.006) and MRSA (P < 0.001), while the MIC for MRSP was significantly lower than that for MRSA (P = 0.001). Conclusions and clinical importance – These in vitro data suggest that miconazole could be a useful therapeutic option for superficial infections caused by meticillin‐susceptible and meticillin‐resistant staphylococci, but proper clinical investigation is required.  相似文献   

Out-patient antimicrobial drug use in dogs and cats for new disease events from community companion animal practices in Ontario     

Murphy CP  Reid-Smith RJ  Boerlin P  Weese JS  Prescott JF  Janecko N  McEwen SA 《The Canadian veterinary journal. La revue veterinaire canadienne》2012,53(3):291-298

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Antimicrobial selective pressure in pet-owning healthcare workers     

Lloyd DH  Loeffler A  Nuttall T  Weese JS 《The Veterinary record》2012,170(8):211-212

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