Antimicrobial resistance in bacteria from horses: Epidemiology of antimicrobial resistance          下载免费PDF全文

T. W. Maddox  P. D. Clegg  N. J. Williams  G. L. Pinchbeck 《Equine veterinary journal》2015,47(6):756-765

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections. While the epidemiology of antimicrobial resistance in bacteria from man has been studied extensively, less work has been undertaken in companion animals, particularly horses. Methicillin‐resistant Staphylococcus aureus has been identified as a cause of infections, with a low prevalence of nasal carriage by horses in the community but higher for hospitalised horses. Molecular characterisation has shown methicillin‐resistant Staphylococcus aureus strains either to be predominantly of types associated with horses or of sequence type ST398. Antimicrobial‐resistant Escherichia coli (including multidrug‐resistant and extended spectrum β‐lactamase‐producing isolates) have caused infections and been documented in faecal carriage by horses, with many significant resistance mechanisms identified. More sporadic reports and molecular characterisation exist for resistance in other bacteria such as enterococci, Salmonella, Acinetobacter and Pseudomonas species. Limited work has been undertaken evaluating risk factors and much of the epidemiology of antimicrobial resistance in bacteria from horses remains to be determined.  相似文献   

Neuropharmacological lesion localization in idiopathic Horner's syndrome in Golden Retrievers and dogs of other breeds          下载免费PDF全文

Katherine M. Simpson  David L. Williams  Giunio B. Cherubini 《Veterinary ophthalmology》2015,18(1):1-5

  相似文献   

Water intake,faecal output and intestinal motility in horses moved from pasture to a stabled management regime with controlled exercise          下载免费PDF全文

S. Williams  J. Horner  E. Orton  M. Green  S. McMullen  A. Mobasheri  S. L. Freeman 《Equine veterinary journal》2015,47(1):96-100

  相似文献   

Soil health cluster analysis based on national monitoring of soil indicators     

Fiona M. Seaton  Gaynor Barrett  Annette Burden  Simon Creer  Eleonora Fitos  Angus Garbutt  Rob I. Griffiths  Pete Henrys  Davey L. Jones  Patrick Keenan  Aidan Keith  Inma Lebron  Lindsay Maskell  M. Gloria Pereira  Sabine Reinsch  Simon M. Smart  Bronwen Williams  Bridget A. Emmett  David A. Robinson 《European Journal of Soil Science》2021,72(6):2414-2429

  相似文献   

Twin quasars found     

Williams S 《Science (New York, N.Y.)》1990,247(4947):1179

  相似文献   

High-Pressure Melting of (Mg,Fe)SiO3-Perovskite     

Heinz DL  Knittle E  Sweeney JS  Williams Q  Jeanloz R 《Science (New York, N.Y.)》1994,264(5156):279-280

  相似文献   

Soil radon and elemental mercury distribution and relation to magmatic resurgence at long valley caldera     

Williams SN 《Science (New York, N.Y.)》1985,229(4713):551-553

The response of a large geothermal system to magmatic resurgence was analyzed by a survey of soil gas radon and elemental mercury at 600 sites in the silicic Long Valley Caldera, California. The broad geochemical anomaly over the caldera has superimposed on it a small zone of pronounced radon enrichment and mercury depletion coincident with the surface projection of a postulated dike of rising magma. Soil gas geochemistry studies can complement traditional geophysical and geodetical methods in the evaluation of potential volcanic eruption hazards.  相似文献   

Society in the Scientific Revolution     

INTERIM-COMMITTEE ON THE SOCIAL ASPECTS OF SCIENCE  Commoner B  Lasker G  Leake CD  Williams B  Pigman W 《Science (New York, N.Y.)》1956,124(3234):1231

  相似文献   

Ice flexure forced by internal wave packets in the arctic ocean     

Czipott PV  Levine MD  Paulson CA  Menemenlis D  Farmer DM  Williams RG 《Science (New York, N.Y.)》1991,254(5033):832-835

Tiltmeters on the Arctic Ocean were used to measure flexure of the ice forced by an energetic packet of internal waves riding the crest of diurnal internal bores emanating from the Yermak Plateau, north of the Svalbard Archipelago. The waves forced an oscillatory excursion of 36 microradians in tilt of the ice, corresponding to an excursion of 16 micrometers per second in vertical velocity at the surface and of 3.5 millimeters in surface displacement. Strainmeters embedded in the ice measured an excursion of 3 x 10(-7) in strain, consistent with ice flexure rather than compression. The measured tilt is consistent with direct measurements of excursions in horizontal current near the surface (12 centimeters per second) and in vertical displacement (36 meters) of the pycnocline 100 meters below the surface.  相似文献   

Immunogenicity of synthetic peptides from circumsporozoite protein of Plasmodium falciparum   总被引：24，自引：0，他引：24  

W R Ballou  J Rothbard  R A Wirtz  D M Gordon  J S Williams  R W Gore  I Schneider  M R Hollingdale  R L Beaudoin  W L Maloy 《Science (New York, N.Y.)》1985,228(4702):996-999

In a study of recombinant proteins that might be useful in developing a vaccine against malaria, synthetic peptides from the circumsporozoite (CS) protein of Plasmodium falciparum were found to be immunogenic for mice and rabbits. Antibody to peptides from the repeating region of the CS protein recognized native CS protein and blocked sporozoite invasion of human hepatoma cells in vitro. Antibodies to peptides from regions I and II had no biologic activity, although antibody to region I recognized processed CS protein by Western blot analysis. These data support the feasibility of developing a vaccine against the sporozoite stage of the malaria parasite by using synthetic peptides of the repeating region of the CS protein conjugated to a carrier protein.  相似文献