Comparison of serum and plasma thyroxine determinations in horses   总被引：1，自引：0，他引：1  

D Hightower  L Miller  J R Kyzar 《Journal of the American Veterinary Medical Association》1971,159(4):449-450

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Background for a mission     

Miller FD 《Science (New York, N.Y.)》1976,194(4264):515-516

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Optical Communications Research Progress: Laser wavelength techniques differing in timing and complexity improve electrical communications     

Miller SE 《Science (New York, N.Y.)》1970,170(3959):685-695

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Portable egg candling booth     

L T Miller  W K Durfee  V J Yates 《American journal of veterinary research》1969,30(10):1893-1895

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ECG of the month. Sick sinus syndrome     

M S Miller  L P Tilley 《Journal of the American Veterinary Medical Association》1984,184(4):423-425

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Canine protothecosis: review of the literature and report of an additional case   总被引：2，自引：0，他引：2  

G Migaki  R L Font  R M Sauer  W Kaplan  R L Miller 《Journal of the American Veterinary Medical Association》1982,181(8):794-797

A review of protothecosis in dogs revealed that this malady usually begins in the gastrointestinal tract and progresses to systemic involvement. Clinical signs generally include bloody diarrhea or blood-stained feces as well as blindness, ataxia, and polyuria. Histologically, myriads of protothecal organisms in different stages of development are found in the granulomatous lesions. Two main species have been culturally identified: Prototheca zopfii and P wickerhamii. In the absence of cultural studies, species identification can be accomplished readily by immunofluorescence. The present case involved P zopfii infection in a 5-year-old female Cocker Spaniel that had bloody diarrhea, with a history of bloody diarrhea 6 months earlier.  相似文献   

A short review of transmissible spongiform encephalopathies, and guidelines for managing risks associated with chronic wasting disease in captive cervids in zoos.     

Dominic Travis  Michele Miller 《Journal of zoo and wildlife medicine》2003,34(2):125-133

The transmissible spongiform encephalopathies (TSEs) represent an emerging group of diseases that have been labeled as "prion diseases" because of the recent characterization of the infectious agent. TSEs are caused by prions, which induce neurodegenerative fatal diseases in humans and animals. Some TSEs (scrapie and kuru), have existed in both animals and humans for a very long time, whereas others such as bovine spongiform encephalopathy and variant Creutzfeld-Jakob disease have either recently emerged or are more thoroughly described and recognized. It is obvious that the medical community will be forced to consider these diseases in humans and animals for the future. This article offers a short review of the TSEs of immediate concern to zoo and wildlife veterinarians and wildlife biologists and suggests risk management strategies for the prevention of these diseases, with special focus on chronic wasting disease of cervids in North America.  相似文献   

Detection, quantification, and pharmacokinetics of furosemide and its effects on urinary specific gravity following IV administration to horses     

Dirikolu L  Lehner AF  Hughes C  Karpiesiuk W  Camargo FC  Harkins JD  Woods WE  Bosken JM  Boyles J  Troppmann A  Fisher M  Tobin T 《Veterinary therapeutics : research in applied veterinary medicine》2003,4(4):350-363

Furosemide is a potent loop diuretic used for the prevention of exercise-induced pulmonary hemorrhage in horses. This drug may interfere with the detection of other substances by reducing urinary concentrations, so its use is strictly regulated. The regulation of furosemide in many racing jurisdictions is based on paired limits of urinary SG (<1.010) and serum furosemide concentrations (>100 ng/ml). To validate this regulatory mechanism, a liquid chromatography/mass spectrometry/mass spectrometry method employing a solid-phase extraction procedure and furosemide-d5 as an internal standard was developed. The method was used to determine the pharmacokinetic parameters of furosemide in equine serum samples and its effects on urinary SG after IV administration (250 mg) to 10 horses. Pharmacokinetic analysis showed that serum concentrations of furosemide were well described by a two-compartmental open model. Based on results in this study, it is very unlikely for horses to have serum furosemide concentrations greater than 100 ng/ml or urine SG less than 1.010 at 4 hours after administration (250 mg IV). However, it should be remembered that urine SG is a highly variable measurement in horses, and even without furosemide administration, some horses might naturally have urine SG values less than 1.010.  相似文献   

Waste management: small animal practice     

Krauss AJ;AVMA Committee on Environmental Issues 《Journal of the American Veterinary Medical Association》2003,223(1):53-54

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Prophylactic use of decoquinate for infections with Cryptosporidium parvum in experimentally challenged neonatal calves     

Moore DA  Atwill ER  Kirk JH  Brahmbhatt D  Herrera Alonso L  Hou L  Singer MD  Miller TD 《Journal of the American Veterinary Medical Association》2003,223(6):839-845

OBJECTIVE: To evaluate the effect of daily oral administration of decoquinate to neonatal calves experimentally challenged with various numbers of Cryptosporidium parvum oocysts. DESIGN: Clinical trial. ANIMALS: 75 calves. PROCEDURE: Calves were purchased from a commercial dairy during a 5-week period. Calves were housed in individual hutches and fed milk replacer with or without decoquinate (2 mg/kg [0.9 mg/lb per day]). Calves were randomly assigned to treatment and 1 of 5 challenge groups (0, 50, 100, 1000, or 10,000 C. parvum oocysts in 60 mL of saline [0.9% NaCl] solution administered p.o. on the day after arrival). Calves were maintained in the study for as long as 28 days. Calves were clinically assessed for diarrhea and dehydration. Fecal samples were submitted for oocyst enumeration 3 times each week. RESULTS: Treatment did not affect number of days to first watery feces (diarrhea), number of days to first oocyst shedding, or duration of diarrhea or oocyst shedding. Duration of oocyst shedding was significantly associated with challenge dose of oocysts administered to calves and number of days to first oocyst shedding. Duration of diarrhea and number of days to first oocyst shedding were significantly associated with week of arrival and number of days to first watery diarrhea. CONCLUSIONS AND CLINICAL RELEVANCE: Daily treatment with decoquinate at the dosage used in this study did not affect oocyst shedding or clinical signs associated with cryptosporidiosis. However, there was an indication that if the number of oocysts calves received could be reduced, then the duration of oocyst shedding and, hence, environmental loading of C. parvum oocysts could be reduced.  相似文献