Sonographic findings of pinpoint hyperechoic foci in the small intestine,liver, and mesenteric lymph nodes are indicative of canine Heterobilharzia americana infection     

Valentina S. Moshnikova  Lindsey J. Gilmour  Audrey K. Cook  Michelle Fabiani 《Veterinary radiology & ultrasound》2020,61(5):583-591

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Empirical analysis of transcriptional activity in the Arabidopsis genome     

Yamada K  Lim J  Dale JM  Chen H  Shinn P  Palm CJ  Southwick AM  Wu HC  Kim C  Nguyen M  Pham P  Cheuk R  Karlin-Newmann G  Liu SX  Lam B  Sakano H  Wu T  Yu G  Miranda M  Quach HL  Tripp M  Chang CH  Lee JM  Toriumi M  Chan MM  Tang CC  Onodera CS  Deng JM  Akiyama K  Ansari Y  Arakawa T  Banh J  Banno F  Bowser L  Brooks S  Carninci P  Chao Q  Choy N  Enju A  Goldsmith AD  Gurjal M  Hansen NF  Hayashizaki Y  Johnson-Hopson C  Hsuan VW  Iida K  Karnes M  Khan S  Koesema E  Ishida J  Jiang PX  Jones T  Kawai J  Kamiya A  Meyers C  Nakajima M 《Science (New York, N.Y.)》2003,302(5646):842-846

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Posttranslational modification of pili upon cell contact triggers N. meningitidis dissemination   总被引：1，自引：0，他引：1  

Chamot-Rooke J  Mikaty G  Malosse C  Soyer M  Dumont A  Gault J  Imhaus AF  Martin P  Trellet M  Clary G  Chafey P  Camoin L  Nilges M  Nassif X  Duménil G 《Science (New York, N.Y.)》2011,331(6018):778-782

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Field investigations and multi‐indicators for shallow water lagoon management: perspective for societal benefit     

Patrice Brehmer  Thang Do Chi  Thierry Laugier  FRANÇOIS GALGANI  Francis Laloë  Audrey M. Darnaude  Annie Fiandrino  David Mouillot 《水产资源保护:海洋与淡水生态系统》2011,21(7):728-742

Exposure to the Neurotoxic Dinoflagellate,Alexandrium catenella,Induces Apoptosis of the Hemocytes of the Oyster,Crassostrea gigas     

Walid Medhioub  Simon Ramondenc  Audrey Sophie Vanhove  Agnes Vergnes  Estelle Masseret  Veronique Savar  Zouher Amzil  Mohamed Laabir  Jean Luc Rolland 《Marine drugs》2013,11(12):4799-4814

This study assessed the apoptotic process occurring in the hemocytes of the Pacific oyster, Crassostrea gigas, exposed to Alexandrium catenella, a paralytic shellfish toxins (PSTs) producer. Oysters were experimentally exposed during 48 h to the toxic algae. PSTs accumulation, the expression of 12 key apoptotic-related genes, as well as the variation of the number of hemocytes in apoptosis was measured at time intervals during the experiment. Results show a significant increase of the number of hemocytes in apoptosis after 29 h of exposure. Two pro-apoptotic genes (Bax and Bax-like) implicated in the mitochondrial pathway were significantly upregulated at 21 h followed by the overexpression of two caspase executor genes (caspase-3 and caspase-7) at 29 h, suggesting that the intrinsic pathway was activated. No modulation of the expression of genes implicated in the cell signaling Fas-Associated protein with Death Domain (FADD) and initiation-phase (caspase-2) was observed, suggesting that only the extrinsic pathway was not activated. Moreover, the clear time-dependent upregulation of five (Bcl2, BI-1, IAP1, IAP7B and Hsp70) inhibitors of apoptosis-related genes associated with the return to the initial number of hemocytes in apoptosis at 48 h of exposure suggests the involvement of strong regulatory mechanisms of apoptosis occurring in the hemocytes of the Pacific oyster.  相似文献   

Gallbladder Mucocele: The Endocrine Connection     

Audrey K Cook 《Advances in Small Animal Medicine and Surgery》2013,26(6):1-3

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Field phenotyping of water stress at tree scale by UAV-sensed imagery: new insights for thermal acquisition and calibration     

David Gómez-Candón  Nicolas Virlet  Sylvain Labbé  Audrey Jolivot  Jean-Luc Regnard 《Precision Agriculture》2016,17(6):786-800

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Bioactivity-guided fractionation of the lipoxygenase and cyclooxygenase inhibiting constituents from Chisocheton polyandrus Merr     

Chan KY  Mohamad K  Ooi AJ  Imiyabir Z  Chung LY 《Fitoterapia》2012,83(5):961-967

Lipoxygenase (LOX)-inhibiting compounds from the leaves of Chisocheton polyandrus Merr. were isolated in this study using a bioactivity-guided fractionation technique. Two dammarane triterpenoids, dammara-20,24-dien-3-one (1) (IC(50)=0.69±0.07 μM) and 24-hydroxydammara-20,25-dien-3-one (2) (IC(50)=1.11±0.38 μM), were isolated and identified based on the soybean LOX assay. Dammara-20,24-dien-3-one (1) exhibited dual inhibition of both human 5-LOX (IC(50)=24.27±2.92 μM) and cyclooxygenase-2 (COX-2) (IC(50)=3.17±0.90 μM), whereas 24-hydroxydammara-20,25-dien-3-one (2) did not exhibit any significant inhibitory effects. This report is the first to detail the inhibition of LOX and COX by both C. polyandrus and its isolated compounds.  相似文献   

Low dietary calcium in European postmenopausal osteoporotic women     

Bruyere O  De Cock C  Mottet C  Neuprez A  Malaise O  Reginster JY 《Public health nutrition》2009,12(1):111-114

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Intrahepatic portosystemic venous shunt in a neonatal roan antelope (Hippotragus equinus cottoni).     

Brad A Lock  Scott B Citino  Audrey Pickup 《Journal of zoo and wildlife medicine》2005,36(3):546-549

A 6-day-old, female roan antelope (Hippotragus equinus cottoni) was diagnosed with a single intrahepatic portosystemic venous shunt at necropsy. Clinical signs had included weakness, lethargy, hypothermia, diarrhea, and a weak suckle response. Multiple seizure episodes were associated with hypoglycemia and characterized by vocalization, muscle fasciculations, and disorientation. Hematologic abnormalities included anemia with hypochromasia, anisocytosis, poikilocytosis, and leukopenia with neutropenia and lymphopenia. Serum biochemical abnormalities included elevations in blood urea nitrogen and total serum bile acid concentration. A portosystemic vascular anomaly should be a differential diagnosis for nonthriving, exotic ruminant calves with overt or subtle neurologic signs, persistent hypoglycemia, and/or elevated bile acids. In very young calves, total bile acid concentration may be more useful in establishing a diagnosis than blood ammonia concentration.  相似文献