Anti-inflammatory effects of a Houttuynia cordata supercritical extract     

Sunhee Shin  Seong Soo Joo  Jeong Hee Jeon  Dongsun Park  Min-Jung Jang  Tae-Ook Kim  Hyun-Kyu Kim  Bang Yeon Hwang  Ki-Yon Kim  Yun-Bae Kim 《Journal of veterinary science (Suw?n-si, Korea)》2010,11(3):273-275

Anti-inflammatory effects of Houttuynia cordata supercritical extract (HSE) were investigated in a carrageenan-air pouch model. HSE (200 mg/kg, oral) suppressed exudation and albumin leakage, as well as inflammatory cell infiltration. Dexamethasone (2 mg/kg, i.p.) only decreased exudation and cell infiltration, while indomethacin (2 mg/kg, i.p.) reduced exudate volume and albumin content. HSE lowered tumor-necrosis factor (TNF)-α and nitric oxide (NO), as well as prostaglandin E₂ (PGE₂). Dexamethasone only reduced TNF-α and NO, while indomethacin decreased TNF-α and PGE₂. The suppressive activity of HSE on NO and PGE₂ production was confirmed in RAW 264.7. These results demonstrate that HSE exerts anti-inflammatory effects by inhibiting both TNF-α-NO and cyclooxygenase II-PGE₂ pathways.  相似文献   

Rose (Rosa hybrida L.) EST-derived microsatellite markers and their transferability to strawberry (Fragaria spp.)     

Young Hoon Park  Seong Gyu Ahn  Young Mi Choi  Hye Jeong Oh  Dong Chun Ahn  Jin Gi Kim  Jum Soon Kang  Young Whan Choi  Byoung Ryong Jeong 《Scientia Horticulturae》2010

The ‘Genome database for Rosaceae (GDR)’ provides a large collection of expressed sequence tags (ESTs) harboring simple sequence repeats (SSRs) from several Rosaceae genera, including Rosa (rose). Primer pairs flanking SSR were designed for 312 unique Rosa ESTs based on GDR database. Eight rose (Rosa hybrida L.) genotypes were tested for PCR amplification, and 287 (92%) of the primer pairs generated allele-specific PCR bands that were readily scored. From 183 (63.7%) primer pairs that evidenced polymorphic alleles among the eight rose cultivars, 20 pairs evidencing EST sequence homology to known gene functions and high levels of polymorphism were selected and utilized for DNA fingerprinting and genetic diversity assessments of 47 rose hybrids. A total of 202 polymorphic bands were scored and generated unique fingerprints for each rose hybrid. The Nei–Li genetic similarity coefficients among 1081 pair-wise comparisons of 47 cultivars exhibited a broad range of genetic variations from 0.30 (‘Grand King’ and ‘Carnival’) to 0.99 (‘First Red’ and ‘Red Champ’). UPGMA cluster analysis divided 47 hybrids into five major groups and two sub-groups. The cross-species transferability of 273 EST-SSR primer pairs was evaluated using four genotypes of the strawberry, a genus member of the Rosaceae family. PCRs on the DNA samples of strawberry were successful for 165 primer pairs; among these, 123 pairs amplified 243 polymorphic bands. As surrogates of the marker transfer, the phenetic relationship among the four strawberry genotypes was evaluated. Genetic similarity coefficients varied from 0.78 (‘Maehyang’ and ‘Janghyee’) to 0.64 (‘Janghyee’ and ‘Pragana’). The results of cluster analysis showed that the three octaploid strawberry cultivars were quite similar, whereas the diploid ‘Pragana’ was related distantly at the genomic DNA level. The EST-SSR markers developed in the present study can be efficiently utilized for genetic diversity studies in Rosaceae.  相似文献   

Review of rice in Korea: current status,future prospects,and comparisons with rice in other countries     

Jeong  O-Young  Park  Hyeon-Su  Baek  Man-Kee  Kim  Woo-Jae  Lee  Geon-Mi  Lee  Chang-Min  Bombay  Maurene  Ancheta  Melanie Banzon  Lee  Jeom-Ho 《Journal of Crop Science and Biotechnology》2021,24(1):1-11

Journal of Crop Science and Biotechnology - Rice has been grown as a staple food in South Korea for several millennia. However, its status has not stayed constant as a result of changes in South...  相似文献   

Mass production of rubusoside using a novel stevioside-specific β-glucosidase from Aspergillus aculeatus     

Ko JA  Kim YM  Ryu YB  Jeong HJ  Park TS  Park SJ  Wee YJ  Kim JS  Kim D  Lee WS 《Journal of agricultural and food chemistry》2012,60(24):6210-6216

Rubusoside (R) is a natural sweetener and a solubilizing agent with antiangiogenic and antiallergic properties. However, currently, its production is quite expensive, and therefore, we have investigated nine commercially available glycosidases to optimize an economically viable R-production method. A stevioside (ST)-specific β-glucosidase (SSGase) was selected and purified 7-fold from Aspergillus aculeatus Viscozyme L by a two-step column chromatography procedure. The 79 kDa protein was stable from pH 3.0 to pH 7.0 at 50-60 °C. Hydrolysis of ST by SSGase produced R and steviol monoglucosyl ester as determined by (1)H and (13)C nuclear magnetic resonance (NMR). Importantly, SSGase showed higher activity toward ST than other β-linked glucobioses. The optimal conditions for R production were 280 mM ST and 16.6 μL of SSGase at pH 5.1 and 63 °C. This is the first discussion detailing the production of R by enzymatic hydrolysis of ST and is useful for the food additive and pharmaceutical industries.  相似文献   

Characterization and mechanical properties of prepolymer and polyurethane block copolymer with a shape memory effect     

Jae?Whan?ChoEmail author  Yong?Chae?Jung  Sun?Hwa?Lee  Byoung?Chul?Chun  Yong-Chan?Chung 《Fibers and Polymers》2003,4(3):114-118

The prepolymer and the final polyurethane (PU) block copolymer were synthesized by reacting 4,4-methylene bis(phenylisocyanate) with poly(tetramethylene glycol) and the prepolymer with 1,4-butanediol as a chain extender, respectively, to investigate the relation between phase separation and it’s resulting properties. According to FT-IR data, the phase separation of hard and soft segments in the prepolymer and the PU block copolymer grew bigger by increasing the hard segment content, and the PU showed more dominant phase separation than the prepolymer. The heat of fusion due to soft segments decreased in both the prepolymer and the PU by increasing the hard segment content, whereas the heat of fusion due to hard segments increased in the PU did not appear in the prepolymers. The breaking stress and modulus of the prepolymer increased by increasing the hard segment content, and the elongation at break decreased gradually, and the PU showed the highest breaking stress and modulus at 58 % hard segment content. However, the best shape recovery of the PU was obtained at 47 % hard segment content due to the existence of proper interaction among the hard segments for shape memory effect. Consequently, the mechanical properties and shape memory effect of the PU were influenced by the degree of phase separation, depending on the incorporation of chain extender as well as the hard segment content.  相似文献   

Study on the strength retention of technical cord yarn     

Dae Hwan Cho  Youngjin Jeong 《Fibers and Polymers》2006,7(3):305-309

This research studies the factors which influence the tensile strength of tire cords. Five yarn samples are made by changing the spinning conditions and viscosity to get various physical properties. Different twisting methods are introduced and the yarns are twisted under different processing conditions for each twisting process. With the experimental results, various analyses are performed to find the important factors in retaining strength after the twisting process. SEM and optical microscopic photographs are taken along with some measurements to assist the analysis.  相似文献   

Aroma finishing of PET fabrics with PVAc nanoparticles containing lavender oil     

Sung Ok Sohn  So Min Lee  Yun Mi Kim  Jeong Hyun Yeum  Jin Hyun Choi  Han Do Ghim 《Fibers and Polymers》2007,8(2):163-167

A durable aroma finishing for PET fabric was carried out by adopting poly(vinyl acetate) (PVAc) nanoparticles containing lavender oil (LO) in core. Relatively small size of PVAc nanoparticles (ca. 244 nm of mean particle diameter) was expected to resist the frictional destruction of the particles, which is frequently observed in cases of microcapsules. PVAc nanoparticles containing LO in core were prepared by emulsification-diffusion method and their application as an aroma releasing agent for PET fabrics was assessed through the observation of releasing profiles of LO in ethanol for experimental acceleration. Melamine-formaldehyde (MF) microcapsules containing LO were also prepared and treated on fabrics for comparison. PVAc nanoparticles treated on PET fabric showed higher initial releasing amount, which was ascribed to the enhanced surface area. After 2 days of releasing, PET fabric treated with PVAc nanoparticles showed slower and more stable releasing profile and reached about 12 ppm of cumulative release after 16 days, which was under two thirds of that with MF microcapsules. PVAc nanoparticles can be used as an agent for durable aroma finishing of PET fabrics.  相似文献   

The mechanical properties and abrasion behavior of warp knitted fabrics for footwear     

Youn?Hee?Jeon  Won?Young?Jeong  Jung?Woo?Park  Seung?Kook?AnEmail author 《Fibers and Polymers》2003,4(4):151-155

The abrasion behavior of three kinds of warp knitted fabrics, which are normally used for upper sole of footwear, was evaluated. We measured the changes of mechanical and structural properties of each sample as abrasion cycle increased. Each sample showed similar trends in compression and surface properties but there were significant differences in abrasion rate among the samples. The mechanical properties showed remarkable differences with directions. The frictional coefficient (MIU) of fabric surface increased at the beginning of abrasion and decreased as abrasion cycles increased. The weight and thickness of the fabric linearly decreased with abrasion cycles. The surface roughness (SMD) and the compressional resilience (RC) decreased as abrasion cycles increased while compressional energy (WC) increased.  相似文献   

Antioxidant activities of Korean rice wine concentrates     

Jeong JW  Nam PW  Lee SJ  Lee KG 《Journal of agricultural and food chemistry》2011,59(13):7039-7044

The antioxidant activities of six Korean rice wine (KRW) concentrates were measured by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and lipid/malonaldehyde (MA) assays. In the DPPH assay, the antioxidant activities of the KRW concentrates, including Maesilju (MSJ), Kookhwaju-1 (KHJ-1), Kookhwaju-2 (KHJ-2), Gugijaju (GGJ), Sasamju (SSJ), and Sogokju (SGJ), were 40%, 66%, 64%, 35%, 35%, and 63%, respectively. Furthermore, the concentrates inhibited the formation of MA from cod liver oil by 49%, 83%, 75%, 82%, 89%, and 90%, respectively, according to the lipid/MA assay. The sample wines were also analyzed for pH, titratable acidity, soluble solids (°Bx), and reducing sugars. The antioxidant activities of volatile extracts of the KRWs extracted by a solvent assisted flavor evaporation (SAFE) apparatus were evaluated by aldehyde/carboxylic acid assay. The volatile extracts of MSJ, KHJ-1, KHJ-2, GGJ, SSJ, and SGJ inhibited the oxidation of hexanal by 97%, 99%, 90%, 90%, 50%, and 51%, respectively. Among the nonvolatile extracts of KRWs, KHJ-2 showed the highest inhibitory effect on MA formation.  相似文献   

Influenza virus neuraminidase inhibitory activity of phlorotannins from the edible brown alga Ecklonia cava     

Ryu YB  Jeong HJ  Yoon SY  Park JY  Kim YM  Park SJ  Rho MC  Kim SJ  Lee WS 《Journal of agricultural and food chemistry》2011,59(12):6467-6473

Influenza A virus infections continue to pose a major threat to humans and several animal species. Neuraminidase (NA) is one of the most promising targets for the development of drugs against influenza viruses because of its critical role in the viral life cycle. During the course of a search for NA inhibitors from edible natural sources, we found that the ethyl acetate layer of ethanol extracts of Ecklonia cava showed extremely high NA-inhibitory activity (72.1% inhibition at 30 μg/mL). Bioactivity-guided fractionation of the ethyl acetate layer yielded five phlorotannins, identified as phloroglucinol (1), eckol (2), 7-phloroeckol (3), phlorofucofuroeckol (4), and dieckol (5). The inhibitory activities of these compounds (1-5) against NAs from group-1 (A/Bervig_Mission/1/18 [H1N1], A/PR/8/34 [H1N1]) and group-2 (A/Hong Kong/8/68 [H3N2], A/Chicken/Korea/MS96/96 [H9N2]) influenza A were evaluated to determine potencies and kinetic behavior. Analyses using various in vitro influenza A virus NA assays showed that all five phlorotannin derivatives were selective NA inhibitors. Of the phlorotannins, phlorofucofuroeckol (4) exhibited the most potent inhibitory activities toward group-1 NAs (IC?? values, 4.5 and 14.7 μM), whereas dieckol (5) potently inhibited group-2 NAs. Kinetic analyses indicated that compounds 1-5 were all noncompetitive. Notably, these noncompetitive inhibitors synergized with oseltamivir to enhance the NA-inhibitory effects of oseltamivir.  相似文献