Porcine surfactant in treatment of LPS-induced early-stage acute lung injury in rats     

WANG Yi-qun  SUN Yu  YANG Rui  ZHONG Ji-gen  LU Jian 《园艺学报》2007,23(8):1583-1586

AIM: To evaluate the therapeutic efficacy of intratracheal instillation of porcine pulmonary surfactant (PPS) in rats with lipopolysaccharides (LPS)-induced early-stage ALI in this study.METHODS: SD rats weighing 200 g-300 g were randomly divided into 4 groups: LPS (1.5 mg·kg-1)+saline,LPS+PPS 100 mg·kg^-1,LPS+PPS 150 mg·kg^-1,LPS+PPS 200 mg·kg^-1.The PaO₂ and PaCO₂,as well as survival rate of rats were examined for 6 h after the start of PPS-instillation.Then,rats were killed and lungs were immediately removed for lung index (LI) and histological analysis.The bronchoalveolar lavage fluid (BALF) was collected for measurement of total protein (TP) contents,TNF-α level and white blood cell(WBC) numbers.RESULTS: Significantly increased PaO₂,reduced mortality rate,decreased total protein and TNF-α contents in BAL,as well as lung index and meliorated histological appearance were observed in three PPS-treated groups compared with group given saline after LPS (P<0.05).The therapeutic effect in PPS150 and PPS200 groups was better than that in PPS100 group.CONCLUSION: Intratracheal PPS instillation provides protective effect on acute lung injury in rats induced by LPS.  相似文献   

Research Advances in Escherichia coli K1 Penetration Across Blood-brain Barrier     

LING Chen  ZHANG Qi-wen  SONG Kang  JIANG Jian-jun  YAN Gen-qiang 《中国畜牧兽医》2017,44(3):686-691

E.coli K1 strain is a representative strain of neonatal sepsis and meningitis, which causes disease by blood circulation to the brain. The molecular mechanism of E.coli K1 that adhering and invading the brain microvascular endothelial cells (BMECs) and cross the blood brain barrier (BBB) has been focused on by many scholars. In this review, we focused on the gene regulation mechanisms and signaling pathway of E.coli K1 crossing the blood brain barrier to understand the molecular mechanism of the infection caused by E.coli and provide reference for prevention and treatment programs.  相似文献   

饲料添加剂双乙酸钠的5P营销策略     

谢清若  郑立文  李克林  凌新龙 《畜牧与饲料科学》2011,32(3)

基于产品(product)、价格(price)、地点(place)和推广(promotion)等市场营销4P策略的内容,结合双乙酸钠的特征、应用和市场现状,整合融入营销平台(platform),即从4P策略过渡到5P策略,并对双乙酸钠市场营销的5P策略实施进行了分析与探讨.  相似文献   

农业种植技术和现代农业机械化的相关性分析     

凌杰 《湖南农机》2017,44(4)

近年来,我国对农业生产的重视度越来越高,农业机械化建设和农业种植技术都面临着很大的发展机遇,同时也面临一定的挑战.文章首先阐述了农业机械化的发展历程,然后分析了农业种植技术和农业技术间的相互关系,紧接着又分析了农业机械化发展过程中存在的问题,最后就问题的解决提出了几点建议,希望能够为今后的相关研究提供一定的参考依据.  相似文献   

Effects of CSF-1,IL-1α on CSF-1 receptor gene expression in rat dental follicle cells     

GU Hai-jing  LING Jun-qi  WANG A-dan 《园艺学报》2007,23(8):1602-1605

AIM: To study the effects of colony stimulating factor(CSF-1) and IL-1α on CSF-1 receptor mRNA levels and to determine if the autocrine effect is inhibited through the CSF-1 receptor.METHODS: Rat dental follicle cells were cultured in vitro.The effects of different concentrations of CSF-1 and IL-1α on CSF-1 receptor gene expression were detected by means of RT-PCR.RESULTS: High concentrations of CSF-1 reduced the gene expression of the CSF-1 receptor. IL-1α had no effects on CSF-1 receptor mRNA levels.CONCLUSION: High concentrations of CSF-1 inhibit the expression of CSF-1 receptor.IL-1α has no effect on the expression of CSF-1 receptor mRNA.  相似文献   

丁(鱼岁)不同群体的生化遗传多样性分析     

凌去非  李思发  赵金良  张海军 《上海海洋大学学报》2007,(3):207-211

2002年10-11月,应用聚丙烯酰胺凝胶水平电泳,对我国新疆丁群体和从捷克引进的丁鱼岁群体各30尾个体的ADH、IDH、LDH、SDH、SOD、EST、MDH、ME、6PGDH、G3PDH等10种同工酶和1种肌蛋白进行分析。结果发现,我国丁鱼岁群体在EST-2、SOD、ADH和IDH等4种同工酶存在多态,捷克群体在EST-1、ADH和IDH等3种同工酶存在多态。我国新疆丁群体多态位点比例为28.57%,比捷克丁群体高(21.43%)。平均杂合度分别为0.061 9,也比捷克丁群体高(0.035 7)。捷克丁群体存在一定的杂合子缺失现象。因此,从遗传保护角度,应防止引入我国的捷克丁鱼岁群体进入新疆额尔齐斯河流域进行人工养殖,以免对我国丁天然资源造成污染。  相似文献   

石墙内外——析尤金?奥尼尔《榆树下的欲望》的悲剧主题     

凌晨 《安徽农业大学学报》2004,(5):140-144

尤金?奥尼尔一生着力于现代心理悲剧的创作，以写实的手法展现了二十世纪美国人民灵魂扭曲的可悲心态和美国现代社会的精神窘困的可忧状况，表达了对人生理想之梦的努力探索和幻灭。木文以《榆树下的欲望》为例，从人物内心欲望困扰、社会批判意义及悲剧的终极价值三方面来探讨其显性的、隐性的及终极的悲剧主题。  相似文献   

Cloning and analysis of a novel human CD44 variant     

XIANG Qiu  HE Xiao-song  ZHU Hua  LEI Xun  LING Yue-fu  XIAO Sheng-jun  FAN Cai-wen  HUANG Lan-zhen  WANG Jian-hong 《园艺学报》2008,24(9):1734-1737

  相似文献   

模拟化学实验室在农业院校绿色化学教育中的优势与作用     

凌育赵 《安徽农业科学》2009,35(19):9279-9281

介绍了模拟化学实验室在绿色化学教育中的重要性，分析了模拟化学实验的优势与作用。  相似文献   

辽北花生主产区的生产优势和发展对策   总被引：1，自引：0，他引：1  

凌爽  于成广 《安徽农业科学》2009,37(8):3814-3815

通过对辽宁省北部花生种植区地球化学调查，分析了花生种植区的气候特征和土壤理化性质，阐述了辽北地区花生生产的优势，并针对辽北地区花生生产目前存在的突出问题。  相似文献