Rhinotomy and Rhinostomy for Surgical Treatment of Chronic Rhinitis in Two Rabbits     

Angela M. Lennox 《Journal of Exotic Pet Medicine》2013,22(4):383-392

Chronic rhinitis is a frustrating disease presentation in rabbits for veterinarians to treat and is often characterized by failure to respond to therapy and reoccurrence. Treatment failure of rabbit chronic rhinitis cases may be due to the presence of foreign material and/or bacterial granulomas with or without bony destruction. For these patients, surgical intervention for the purpose of debridement and flushing of the affected nasal area is an effective alternative to promote healing.  相似文献   

Mucocutaneous subdermal plexus flap for complete excision of a malignant dermal and conjunctival melanoma in a dog     

Mihal Kaminsky  Allison Hoffman  Angela E. Ellis 《Veterinary ophthalmology》2023,26(3):243-249

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Quantification of circulating tumour cells over time in dogs with appendicular osteosarcoma     

Tanya F. Wright  Brigitte A. Brisson  Catherine R. Belanger  Angela Tiessen  Victoria Sabine  Karolina Skowronski  Geoffrey A. Wood  Michelle L. Oblak  Anthony J. Mutsaers  William Sears  Dorothee Bienzle 《Veterinary and comparative oncology》2023,21(3):541-550

Enumeration of circulating tumour cells (CTC) has shown promise for prognostication and guidance of therapeutic decisions in human cancers. The objective of this study was to enumerate CTC over time in dogs with naturally occurring osteosarcoma (OSA), and to determine correlation with patient outcome. Twenty-six dogs with OSA and no evidence of metastatic disease at the time of amputation were enrolled. Dogs were assessed for lung metastases and CTC prior to and following amputation, and at each chemotherapy visit. Twenty-one dogs completed the study. Nineteen dogs were euthanized and two were alive and free of metastases. Overall survival time ranged from 88 to 1058 days (median survival time (MST) 374 days). Increased serum alkaline phosphatase activity, advanced age, and higher body weight were significantly associated with lower MST. Dogs with OSA had a mean of 356 (0 to 4443) CTC/10⁶ leukocytes. In 12 of 15 dogs that developed radiographic evidence of metastasis, a pre-metastatic CTC spike was retrospectively detectable on average 36.5 (1–100 days) days prior to metastasis and was associated with significantly shorter MST (301 ± 64 vs. 626 ± 55 days; p = .0107). In a multivariable analysis, dogs with a CTC spike were 10× more likely to die compared with those without. These results suggest that a spike in CTC frequency precedes detection of metastasis in dogs with OSA and is associated with shorter survival. More frequent enumeration of CTC in a larger cohort of dogs with OSA may be warranted.  相似文献   

The genome of the kinetoplastid parasite, Leishmania major     

Ivens AC  Peacock CS  Worthey EA  Murphy L  Aggarwal G  Berriman M  Sisk E  Rajandream MA  Adlem E  Aert R  Anupama A  Apostolou Z  Attipoe P  Bason N  Bauser C  Beck A  Beverley SM  Bianchettin G  Borzym K  Bothe G  Bruschi CV  Collins M  Cadag E  Ciarloni L  Clayton C  Coulson RM  Cronin A  Cruz AK  Davies RM  De Gaudenzi J  Dobson DE  Duesterhoeft A  Fazelina G  Fosker N  Frasch AC  Fraser A  Fuchs M  Gabel C  Goble A  Goffeau A  Harris D  Hertz-Fowler C  Hilbert H  Horn D  Huang Y  Klages S  Knights A  Kube M  Larke N  Litvin L  Lord A 《Science (New York, N.Y.)》2005,309(5733):436-442

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Environmental relative humidity affects Schirmer tear test results in normal dogs     

Angela Yoon  Chin‐Chi Liu  Renee T. Carter  Andrew C. Lewin 《Veterinary ophthalmology》2020,23(5):923-926

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Feeding the European hedgehog (Erinaceus europaeus L.)—risks of commercial diets for wildlife     

Angela Gimmel  Ulrike Eulenberger  Annette Liesegang 《Journal of animal physiology and animal nutrition》2021,105(Z1):91-96

The supplemental feeding of wildlife is a worldwide phenomenon. The most widespread and socially accepted example is bird feeding. Commercial hedgehog (Erinaceus europaeus L.) diets are readily available in Switzerland. To test the hypothesis that commercial hedgehog diets are nutritionally inadequate, the following parameters (as taken from the label) of five commercial diets (three dry and two wet) were compared to the natural diet of E. europaeus: List of feed materials, crude ash (CA), crude protein (CP), crude fibre (CF), ether extract (EE) and nitrogen-free extracts (NfE). To test the second hypothesis, that feed labels of commercially available hedgehog diets in Switzerland are in accordance with Swiss and European law, the following parameters were assessed: Type of feed, net quantity, moisture content, instructions for proper use, list of the feed materials and claims. In all dry diets, the first ingredient was cereals (38.8%–50%), whereas in both wet diets, it was meat and meat by-products (51% in one product). Only one product had a CP content comparable to that of the natural diet and four products had a higher NfE content. Overall, the wet products were more comparable to the natural diet, especially regarding CP and NfE content. Of the five examined diets, three were labelled as complete feeds and two as compound feeds. The label analysis revealed inaccuracies and possible misleading information on two products. In conclusion, the use of commercial dry hedgehog diets should be discouraged as they do not resemble the natural diet of E. europaeus and are likely nutritionally inadequate. The commercial wet hedgehog diets should only be used supplementary. The feed labels of commercially available hedgehog diets were not always in compliance with Swiss and European law. The public should be educated about feeding E. europaeus and the risks of commercial diets for wildlife.  相似文献   

Along or across the visual axis: a comparison of two ultrasound screen,needle and transducer orientation techniques     

Chiara Di Franco  Hamaseh Tayari  Samanta Nardi  Angela Briganti 《Veterinary anaesthesia and analgesia》2021,48(1):147-150

ObjectiveTo evaluate two transducer and needle handling methods, along the visual axis (AL) and across the visual axis (AC), in non-skilled and skilled clinicians.Study designProspective randomized crossover study.MethodA total of 26 students with no ultrasound locoregional anaesthesia experience (non-skilled group) and six clinicians experienced and familiar with ultrasound locoregional anaesthesia (skilled group) were enrolled. The non-skilled group was asked to perform two tasks: the first on a phantom and the second on canine cadavers, whilst the skilled group performed only the second task. The tasks consisted of guiding the tip of the needle to a target point (simulated nerve on the jelly phantom and sciatic nerve on the cadavers) using two different methods of needle handling—AL or AC. All operators performed each task three times for each method. The time to drive the needle to the target for the two methods was analysed with a paired Student t test, and the number of times the needle was not visualized on the screen between the groups was compared using an unpaired Student t test. Data are presented as mean ± standard deviation. Value of p < 0.05 was considered significant.ResultsThe AL method, compared with the AC method, resulted in shorter performance time in both skilled (9 ± 5 versus 20 ± 8 seconds for the second task) and non-skilled groups (9 ± 8 versus 17 ± 15 seconds for the first task and 18 ± 11 versus 32 ± 26 seconds for the second task).Conclusion and clinical relevanceIn both groups, the AL method significantly reduced the time to complete the task. Results from this study indicate that the AL method should be the preferred method for learning/teaching ultrasound-guided regional anaesthesia.  相似文献   

Thermoregulatory and physiological responses of nonpregnant,mid-gestation,and late-gestation sows exposed to incrementally increasing dry bulb temperature     

Betty R McConn  Brianna N Gaskill  Allan P Schinckel  Angela R Green-Miller  Donald C Lay  Jr.  Jay S Johnson 《Journal of animal science》2021,99(7)

Gestating sows may be more susceptible to increasing dry bulb temperatures (T_DB) due to greater metabolic heat production and increased body mass, especially as gestation advances. However, there are few studies on the thermoregulatory and physiological responses of sows at differing gestation stages exposed to gradually increasing temperatures. The study objective was to determine the thermoregulatory and physiological responses of nonpregnant (n = 12; parity 3.27 ± 0.86), mid-gestation (59.7 ± 9.6 d pregnant, n = 12; parity 3.25 ± 0.83), and late-gestation (99.0 ± 4.8 d pregnant, n = 12; parity 3.33 ± 0.75) sows exposed to increasing T_DB. Prior to the experiment (5.0 ± 0.7 d), jugular catheters were placed in all sows. During the experiment, the T_DB was increased incrementally by 2.45 ± 0.43 °C every 60 min from 19.84 ± 2.15 to 35.54 ± 0.43 °C over 400 min, and relative humidity was recorded at 40.49 ± 18.57%. Respiration rate (RR), heart rate (HR), skin temperature, and vaginal temperature were measured, and blood samples were obtained via the jugular catheter every 20 min. Data were analyzed using PROC MIXED in SAS 9.4. RR increased at a lower T_DB (P < 0.01) in late-gestation sows compared with mid-gestation and nonpregnant sows, but no differences were detected between mid-gestation and nonpregnant sows. Overall, late-gestation sows had greater RR (P < 0.01; 23 ± 2 breaths per min [brpm]) compared with mid-gestation (16 ± 2 brpm) and nonpregnant (15 ± 2 brpm) sows. Late-gestation sows had an overall greater HR (P < 0.01; 84 ± 5 beats per min [bpm]) than mid-gestation (76 ± 5 bpm) and nonpregnant (69 ± 5 bpm) sows. Late-gestation sows had overall reduced bicarbonate and total carbon dioxide levels (P = 0.02; 23.89 ± 1.97 and 25.41 ± 2.07 mmol/L, respectively) compared with mid-gestation (27.03 ± 1.97 and 28.58 ± 2.07 mmol/L, respectively) and nonpregnant (26.08 ± 1.97 and 27.58 ± 2.07 mmol/L, respectively) sows. Moreover, late-gestation sows had overall greater nitric oxide levels (P < 0.01; 248.82 ± 34.54 µM) compared with mid-gestation (110.47 ± 34.54 µM) and nonpregnant (41.55 ± 34.54 µM) sows. In summary, late-gestation sows appear to be more sensitive to increasing T_DB as indicated by thermoregulatory and physiological responses when compared with mid-gestation or nonpregnant sows. The results from this study provide valuable information regarding thermoregulatory thresholds of sows at differing gestation stages.  相似文献   

The nutritional quality and toxin content of wild and cultivated lima beans (Phaseolus lunatus)     

Adolfo De La Vega  Angela Sotelo 《Plant foods for human nutrition (Dordrecht, Netherlands)》1986,36(1):75-83

Proximal analysis, amino acid profile, trypsin inhibitor content, hemagglutinin content and HCN generated from cyanogenic glucosides were determined in four wild and three cultivated varieties ofPhaseolus lunatus. All the wild beans showed a higher protein content than the cultivated beans, but no big differences were found in the other nutrients. The essential amino acid percentage was higher in the cultivated beans than in the wild seeds, which was reflected in the PER determination. The most remarkable difference found between wild and cultivated beans was the high concentration of HCN in all wild varieties. The high concentration of protein found in the wild seed could be a false result from the nitrogen provided by the cyanogenic glucosides.  相似文献   

Colour and chemical changes on photodegraded beech wood with or without red heartwood   总被引：1，自引：0，他引：1  

Luca Calienno  Angela Lo Monaco  Claudia Pelosi  Rodolfo Picchio 《Wood Science and Technology》2014,48(6):1167-1180

The focus of this study was to investigate the chemical and colour changes occurring at different exposure times on artificially photo-irradiated surfaces of normal and red heartwood in beech in order to understand the mechanisms that cause the changes and to evaluate the possibility of usages of beech not only for energy production purposes. In this sense, surface colour modifications are of crucial importance to define the commercial value of beech wood. The artificial photo-irradiation of the wood samples was performed in a Solar Box, equipped with an ultraviolet filter that cuts off the spectrum at 280 nm. Reflectance spectrophotometry and Fourier transform infrared (FTIR) spectroscopy were used to assess artificial sunlight influence. The experimental data were statistically treated to evaluate their significance. Colour monitoring revealed that wood surface colour undergoes an important variation due to photo-irradiation, occurring within the first 24–48 h. Moreover, it was found that the chromatic coordinates (L*a*b*) in normal wood and in red heartwood tended to similar values after 504 h. FTIR spectroscopy allowed for investigating the rate of photodegradation of wood surface due to oxidation reactions of wood components. The results were validated by statistical analysis applied both to the colorimetric and spectroscopic data.  相似文献