Bilateral microphthalmia and aphakia associated with multiple eye abnormalities in a free-living European red deer calf (Cervus elaphus)     

Mutinelli F  Vercelli A  Carminato A  Luchesa L  Pasolli C  Cova M  Marchioro W  Melchiotti E  Vascellari M 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2012,74(4):527-529

A free-living European red deer calf (Cervus elaphus) was euthanized due to bilateral microphthalmia. Lens was missing, replaced by proliferating squamous epithelial cells; hyperplastic squamous cells, sebaceous and mucinous glands were observed within the cornea with the characteristics of inclusion cyst. Findings were consistent with congenital microphthalmia/aphakia, with multiple eye abnormalities.  相似文献   

Extract from the Zooxanthellate Jellyfish Cotylorhiza tuberculata Modulates Gap Junction Intercellular Communication in Human Cell Cultures     

Antonella Leone  Raffaella Marina Lecci  Miriana Durante  Stefano Piraino 《Marine drugs》2013,11(5):1728-1762

On a global scale, jellyfish populations in coastal marine ecosystems exhibit increasing trends of abundance. High-density outbreaks may directly or indirectly affect human economical and recreational activities, as well as public health. As the interest in biology of marine jellyfish grows, a number of jellyfish metabolites with healthy potential, such as anticancer or antioxidant activities, is increasingly reported. In this study, the Mediterranean “fried egg jellyfish” Cotylorhiza tuberculata (Macri, 1778) has been targeted in the search forputative valuable bioactive compounds. A medusa extract was obtained, fractionated, characterized by HPLC, GC-MS and SDS-PAGE and assayed for its biological activity on breast cancer cells (MCF-7) and human epidermal keratinocytes (HEKa). The composition of the jellyfish extract included photosynthetic pigments, valuable ω-3 and ω-6 fatty acids, and polypeptides derived either from jellyfish tissues and their algal symbionts. Extract fractions showed antioxidant activity and the ability to affect cell viability and intercellular communication mediated by gap junctions (GJIC) differentially in MCF-7and HEKa cells. A significantly higher cytotoxicity and GJIC enhancement in MCF-7 compared to HEKa cells was recorded. A putative action mechanism for the anticancer bioactivity through the modulation of GJIC has been hypothesized and its nutraceutical and pharmaceutical potential was discussed.  相似文献   

Prevalence of the polycystic kidney disease and renal and urinary bladder ultrasonographic abnormalities in Persian and Exotic Shorthair cats in Italy     

Bonazzi M  Volta A  Gnudi G  Bottarelli E  Gazzola M  Bertoni G 《Journal of Feline Medicine and Surgery》2007,9(5):387-391

The ultrasonographic findings of kidneys, liver and urinary bladder of 288 Persian and 44 Exotic Shorthair clinically normal cats that underwent screening for polycystic kidney disease (PKD) between July 2003 and December 2005 were reviewed. Cats were divided into two groups, one including cats aged <9 months (group 1) and one cats aged >/=9 months (group 2). Cats were classified as PKD-positive when at least one renal cyst was found. One hundred and thirty-six cats (41.0%) had more than one cyst in at least one kidney. The prevalence of PKD was similar in both groups. Eight PKD-positive cats had cystic livers (5.9%). Other renal abnormalities included a pelvic calculus and a medullary rim sign (MRS). The difference in prevalence of an MRS in group 2 compared to group 1 and the difference between PKD-positive and -negative cats in group 2 were not significant. There was no difference in mean kidney length between PKD-positive and -negative cats in group 2. Urinary bladder anomalies were principally represented by urinary sediment, with prevalence significantly higher in group 2. No difference was detected in group 2 between PKD-positive and -negative cats. In conclusion feline PKD is common in Italy. The ultrasonographic findings of MRS and urinary bladder sediment did not correlate with feline PKD. Urinary bladder sediment is common in Persians and Exotic Shorthairs and more likely in adults.  相似文献   

Tolerance to abiotic stresses in potato plants: a molecular approach     

Antonella Leone  Antonello Costa  Federica Consiglio  Immacolata Massarelli  Emilia Dragonetti  Monica De Palma  Stefania Grillo 《Potato Research》1999,42(2):333-351

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Downy mildew resistance evaluation in 28 grapevine hybrids promising for breeding programs in Trentino region (Italy)     

Silvia Vezzulli  Antonella Vecchione  Marco Stefanini  Luca Zulini 《European journal of plant pathology / European Foundation for Plant Pathology》2018,150(2):485-495

Downy mildew is a major grapevine disease caused by the biotrophic oomycete, Plasmopara viticola. Numerous disease resistance studies of diverse Vitis germplasm have been previously carried out to identify downy mildew resistance sources; however, ratings were mainly reported using leaf disc in vitro testing and foliage field assessment, or upon leaf and cluster field evaluations. In the current study, 28 grapevine hybrid cultivars were screened using leaf disc bioassay, for disease resistance characterization of both existing and wild-collected materials. 16 hybrids were identified as highly resistant or resistant, and will serve as relevant resistance donors in future pre-breeding and breeding programs. All grapevine hybrids were evaluated for foliar and cluster downy mildew resistance in an untreated field trial over three successive years. This study showed that the leaf disc bioassay provided some information on the resistance level of the genotypes under scrutiny, but it was a weak predictor of their resistance level under field conditions on leaves and even more on bunches. These findings are relevant to future applications in both traditional and marker-assisted breeding programs which promote sustainable viticulture.  相似文献   

Weak effects of habitat type on susceptibility to invasive freshwater species: an Italian case study          下载免费PDF全文

Angela Boggero  Alberto Basset  Martina Austoni  Enrico Barbone  Luca Bartolozzi  Isabella Bertani  Alessandro Campanaro  Antonella Cattaneo  Fabio Cianferoni  Giuseppe Corriero  Ambrosius Martin Dörr  A. Concetta Elia  Gentile Francesco Ficetola  Lyudmila Kamburska  Gianandrea La Porta  Sara Lauceri  Alessandro Ludovisi  Elda Gaino  Enzo Goretti  Massimo Lorenzoni  Marina Manca  Aldo Marchetto  Giuseppe Morabito  Francesco Nonnis Marzano  Alessandro Oggioni  Cataldo Pierri  Nicoletta Riccardi  Giampaolo Rossetti  Nicola Ungaro  Pietro Volta  Silvia Zaupa  Diego Fontaneto 《水产资源保护:海洋与淡水生态系统》2014,24(6):841-852

Characterization of flavonoids and pectins from bergamot (Citrus bergamia Risso) peel, a major byproduct of essential oil extraction     

Mandalari G  Bennett RN  Bisignano G  Saija A  Dugo G  Lo Curto RB  Faulds CB  Waldron KW 《Journal of agricultural and food chemistry》2006,54(1):197-203

Bergamot peel is an underutilized byproduct of the essential oil and juice-processing industry. As with other Citrus peels, it still contains exploitable components, such as pectins and flavonoids. Commercial glycoside hydrolases, specifically a combination of pectolytic and cellulolytic enzymes, solubilized a high percentage of the material (81.94%). The flavonoid profile of the peel consisted of characteristic Citrus species flavanone rutinosides and neohesperosides derived from naringenin, eriodictyol, and hesperetin. In addition, a number of minor flavanone and flavone glycosides, not found in orange and lemon peels, were identified. The majority of flavonoids were extracted in the two 70% v/v EtOH extractions. Processing this material clearly has economic potential leading to low environmental impact.  相似文献   

IMAGING DIAGNOSIS—ULTRASONOGRAPHIC APPEARANCE OF SKELETAL MUSCLE METASTASES IN A DOG WITH HEMANGIOSARCOMA          下载免费PDF全文

Martina Fabbi  Stefano Di Palma  Sabrina Manfredi  Giacomo Gnudi  Francesca Miduri  Eleonora Daga  Gabriele Costantino Melis  Ezio Bianchi  Simone Voccia  Antonella Volta 《Veterinary radiology & ultrasound》2017,58(6):E64-E67

A 13‐year‐old spayed female German shepherd dog was presented for acute onset of lethargy, anorexia, and disseminated erythematous skin lesions. Thoracic radiographs and abdominal ultrasonographic findings were consistent with metastatic hemangiosarcoma. Multiple, ill‐defined, irregularly shaped hypoechoic nodules were also detected within the thoracic and abdominal wall. Hemangiosarcoma metastases to the skeletal muscle were confirmed based on histopathological examination. Multivisceral involvement was also confirmed by necropsy. Metastatic neoplasia should be considered as a differential diagnosis for dogs with ill‐defined, irregular, hypoechoic, intramuscular nodules.  相似文献   

Should the domestic buffalo (Bubalus bubalis) be considered in the epidemiology of Bovine Herpesvirus 1 infection?     

Maria Teresa Scicluna  Andrea CaprioliGiorgio Saralli  Giuseppe MannaAntonino Barone  Antonella CersiniGiusy Cardeti  Renato Ugo CondoleoGian Luca Autorino 《Veterinary microbiology》2010

Only limited information is available on the epidemiology and pathogenesis of Bovine Herpesvirus 1 (BoHV-1) in domestic buffalos. In this study, a virulent BoHV-1 field strain isolated from cattle was inoculated into buffaloes to evaluate their susceptibility to the virus and to investigate the establishment of viral latency through clinical, virological and serological investigations. Latency was also studied by attempting viral reactivation using pharmacological induction. Six of seven male, 5 months old buffaloes were intranasally inoculated with BoHV-1; the other animal was kept as negative control. The animals were clinically monitored during the post-infection (P.I.) and the post-pharmacological induction (P.P.) periods. During these periods, nasal and rectal swabs, and blood samples, with and without anticoagulant, were collected at 2–3 day intervals. On culling the animals, 206 days P.I., their trigeminal ganglia and tonsils were collected. No clinical signs referable to BoHV-1 were observed throughout the experimental period. However, seropositivity was detected in all infected animals within day 20 P.I., using BoHV-1 glycoprotein E and glycoprotein B competitive ELISAs (IDEXX) and virus neutralisation test. In real-time PCR (RT-PCR), five of these animals were positive, at least once, for nasal or rectal swabs, during the P.I. period. The sixth infected animal was found positive only in the trigeminal ganglia after culling. Ganglia were also positive for two other animals. Virus isolation in permissive cell-lines was successful for a part of the RT-PCR positive samples. The detected viruses were confirmed by genetic analysis as identical to the inoculated strain. No evidence of infection was observed in the negative control. This study represents the first experimental transmission of BoHV-1 in buffaloes, confirming their susceptibility to infection and their possible role as host/reservoirs of BoHV-1.  相似文献   

Invasive mould infections of the naso-orbital region of cats: a case involving Aspergillus fumigatus and an aetiological review     

Cristina Giordano  Paola Gianella  Stefano Bo  Antonella Vercelli  Chiara Giudice  Daniele Della Santa  Anna Maria Tortorano  Claudio Peruccio  Andrea Peano 《Journal of Feline Medicine and Surgery》2010,12(9):714-723

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