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991.
After very hot summer, 22 sheep from 5 different flocks consisting of approximately 150-200 animals each were diagnosed with facial eczema in September 2005, in southwest Turkey. Photophobia, corneal opacity, severe ulcers of the facial skin, especially localized around the eyes and mouth, and 3% mortality were the most prominent clinical symptoms. GGT levels of the animals were very high and varying between 261- 328 U/l. While the activities of ALT and total bilirubin were elevated and AST was normal in affected sheep. Total bilirubin level was higher than normal. Seven of the 22 sheep were euthanatized and necropsy was performed on all of these animals. Severe icterus, hepatomegaly, enlarged gallbladder, congestion of mesenteric vessels were the common necropsy findings. Histopathological changes of the liver included necrosis of the hepatocytes, cholangiohepatitis characterized by mononuclear inflammatory cell infiltrate in the portal area and mild to severe fibrosis around bile ducts. A diagnosis of sporidesmin toxicosis was made based on the histopathology of the livers, the elevation in liver enzymes, and the development of cutaneous lesions consistent with photosensitization and high spore counts in the ruminal contents. Surviving sheep were treated with procaine penicillin + dihidrostreptomycin sulfate, multivitamin complexes and flunixin meglumine. Additionally, zinc sulphate was also given at a dose of 6 gr per 100 lt drinking water for 28 days. All treated sheep recovered. Pasture spore counts were between 96,300- 267,500 spores/g grass. 相似文献
992.
Giammarioli M Pellegrini C Casciari C De Mia GM 《Veterinary research communications》2008,32(3):255-262
993.
Shiilegdamba E Carpenter TE Perez AM Thurmond MC 《Veterinary research communications》2008,32(3):201-207
Prior to 2000, foot-and-mouth disease (FMD) had not been observed in Mongolia since 1973; however, between April 2000 and
July 2002, Mongolia reported 44 FMD outbreaks that affected cattle, sheep, goats, and camels. The objectives of this study
were to describe the distributions of the 44 reported FMD outbreaks in Mongolia and to assess their spatial clustering and
directions of movement. Official reports were collected to obtain the number and species of animals both affected and at risk,
and the date and geographical coordinates of each outbreak. Significant global and local spatial clusters of reported FMD
outbreaks were identified. Disease spread during the second epidemic moved 76° northeast and the spread of the disease during
the third epidemic moved 110° northwest. FMD outbreaks were clustered intensely close to other FMD-positive counties. These
findings can be used in the future to help plan prevention and control measures in high risk areas. 相似文献
994.
Mestorino N Formentini EA Lucas MF Fernandez C Modamio P Hernández EM Errecalde JO 《Veterinary research communications》2008,32(1):21-33
A comparative pharmacokinetic study was conducted to determine the order and the rate of absorption of triclabendazole (TCBZ)
in cattle and sheep. A commercial suspension of TCBZ (Biofasiolex, Biogénesis S.A., Argentina) was administered at a dose
rate of 10 mg/kg by the oral route to six Holstein female calves and six Corriedale female sheep. The plasma concentration
profiles of the metabolites triclabendazole sulfoxide (TCBZ-SO) and triclabendazole sulfone (TCBZ-SO2) were analysed by means of the non-compartmental method. The order of the absorption process of the active metabolite, TCBZ-SO,
was determined by construction of curves of cumulative absorbed fraction of the drug by means of the Wagner-Nelson method.
The appearance of TCBZ-SO in plasma of cattle and sheep resembles the entry of a constant quantity of drug into the organism
per unit time. This is explained by the reservoir effect of the rumen, which acts as a biological slow-release system for
TCBZ-SO and its precursor TCBZ to the posterior digestive tract where they are absorbed. The plasma concentration profiles
of TCBZ-SO in both species were well described by a one-compartment open model with zero-order process of absorption and first-order
process of elimination. The values of AUC0-∞ and C
max of TCBZ-SO did not differ between species, while other kinetic parameters except for λ
z
had higher values in calves than in sheep. In the case of TCBZ-SO2, t
max was the only parameter that did not differ between species, while other kinetic parameters except for λ
z
had higher values in calves than in sheep. 相似文献
995.
Nikolić A Dimitrijević S Katić-Radivojević S Klun I Bobrć B Djurković-Djaković O 《Acta veterinaria Hungarica》2008,56(3):335-340
To identify areas of risk for canine-related zoonoses in Serbia, the aim of this study was to provide baseline knowledge about intestinal parasites in 151 dogs (65 household pets, 75 stray and 11 military working dogs) from Belgrade. The following parasites, with their respective prevalences, were detected: Giardia duodenalis (14.6%), Ancylostomatidae (24.5%), Toxocara canis (30.5%), Trichuris vulpis (47.0%) and Taenia-type helminths (6.6%). Of all examined dogs, 75.5% (114/151) were found to harbour at least one parasite species. Of these, mixed infections with up to four species per dog occurred in 44.7% (51/114). Infections with all detected species were significantly higher (p < 0.05) in military working (100%) and stray dogs (93.3%) versus household pets (50.8%). Among all parasites, agents with zoonotic potential including Giardia, Ancylostomatidae and Toxocara were detected in 58.3% (88/151) of all examined dogs with a significant difference (p < 0.05) among the subgroups (100%, 62.7% and 46.2% for military working dogs, stray dogs and household pets, respectively). The high prevalence of zoonotic parasites registered in the dog population from a highly urban area in south-eastern Europe indicates a potential risk to human health. Thus, veterinarians should play an important role in helping to prevent or minimise zoonotic transmission. 相似文献
996.
The first weeks of lactation in dairy cows are characterised by elevated bone resorption. The connection between lactation and bone metabolism is still much discussed. In this work, changes in the concentration of plasma parathyroid hormone-related peptide (PTHrP) and markers of bone metabolism were studied in Holstein cows and heifers in the dry period and early lactation to determine the role of PTHrP in the relationship between the rate of bone remodelling and the onset of lactation in dairy cows. Blood samples were taken 14 days before calving ('D-14', n = 23) and then on day 10 ('D+10', n = 21) and day 30 after calving ('D+30', n = 23). Using enzyme immunoassay (EIA), the concentrations of PTHrP, parathyroid hormone (PTH), carboxyterminal cross-linked telopeptide of type I collagen (CTX) and oestradiol and the activity of bone specific alkaline phosphatase (BSALP) were determined. The results showed a statistically significant increase in plasma PTHrP (p < 0.005) and CTX (p < 0.0001) in cows on 'D+10' as compared to 'D-14' and CTX on 'D+30' as compared to 'D-14' (p < 0.0001). Significant negative correlations were found between the concentrations of PTHrP and oestradiol (r = -0.29, p < 0.05) and those of CTX and oestradiol (r = -0.54, p < 0.0001). In nonpregnant heifers (n = 6), the concentration of CTX and the activity of BSALP were significantly higher (p < 0.0001) than in dry cows. The observed increments of PTHrP and bone resorption after parturition reveal adaptations of bone metabolism to lactation in dairy cows. 相似文献
997.
Randhawa SS Dua K Randhawa CS Randhawa SS Munshi SK 《Veterinary research communications》2008,32(8):599-608
The effect of biotin supplementation on various foot lesions and hoof ceramide composition of toe (wall) and sole portions
of hooves was studied in crossbred dairy cattle. Biotin supplementation was done for five months in 14 cattle at a farm and
the other 14 animals kept as control. A significant decline was observed in heel erosions and sole avulsions along with total
disappearance of white line fissures and double soles in the biotin supplemented cattle resulting in decrease in the overall
disease score. Thin layer chromatographs of the hoof lipids revealed 11 types of ceramides in sole lipids and 6 types of ceramides
in toe (wall) lipids. The ceramides were typed and identified according to their Rf values. A qualitative increase in the
density of thin layer chromatographs of sole lipids was observed in biotin supplemented cattle whereas a non-significant difference
in density of thin layer chromatographs of toe lipids was observed after supplementation of biotin. 相似文献
998.
Comparison of mouse and rabbit model for the assessment of strong PGM-containing oil-based adjuvants
Habjanec L Halassy B Vdović V Balija ML Tomasić J 《Veterinary immunology and immunopathology》2008,121(3-4):232-240
Peptidoglycan monomer (PGM) is an adjuvant active molecule with potential for use in human and veterinary vaccine. PGM's action is short-lived in mammals hence its effects might be limited. Novel PGM-containing oil-based formulations have been developed recently by incorporation of PGM into Montanide ISA720 and ISA206 adjuvants with the aim to prolong and improve immunostimulating activities of PGM. In the present work we studied the efficacy of such novel adjuvant formulations using two different antigens, ovalbumin and snake venom, respectively. Novel formulations were also tested in two experimental models, mice and rabbits. In rabbits the incorporation of PGM into oil-based adjuvants led to overall improvement of antigen-specific IgG response. However, in the mouse model, under experimental conditions used, it was not possible to distinguish differences in antigen-specific IgG response among several strong oil-based adjuvant formulations. 相似文献
999.
Conservationists, managers, and land planners are faced with the difficult task of balancing many issues regarding humans
impacts on natural systems. Many of these potential impacts arise from local-scale and landscape-scale changes, but such changes
often covary, which makes it difficult to isolate and compare independent effects arising from humans. We partition multi-scale
impacts on riparian forest bird distribution in 105 patches along approximately 500 km of the Madison and Missouri Rivers,
Montana, USA. To do so, we coupled environmental information from local (within-patch), patch, and landscape scales reflecting
potential human impacts from grazing, invasive plant species, habitat loss and fragmentation, and human development with the
distribution of 28 terrestrial breeding bird species in 2004 and 2005. Variation partitioning of the influence of different
spatial scales suggested that local-scale vegetation gradients explained more unique variation in bird distribution than did
information from patch and landscape scales. Partitioning potential human impacts revealed, however, that riparian habitat
loss and fragmentation at the patch and landscape scales explained more unique variation than did local disturbances or landscape-scale
development (i.e., building density in the surrounding landscape). When distribution was correlated with human disturbance,
local-scale disturbance had more consistent impacts than other scales, with species showing consistent negative correlations
with grazing but positive correlations with invasives. We conclude that while local vegetation structure best explains bird
distribution, managers concerned with ongoing human influences in this system need to focus more on mitigating the effects
of large-scale disturbances than on more local land use issues.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users. 相似文献
1000.
Olga Viedma 《Landscape Ecology》2008,23(6):657-672
Mediterranean landscapes are dynamic systems that undergo temporal changes in composition and structure in response to disturbances,
such as fire. Neither landscape patterns nor driving factors that affect them are evenly distributed in space. Accordingly,
disturbances and biophysical factors interact in space through time. The aim of this paper is to assess the relative influence
of topography and fire on the landscape patterns of a large forested area located in Sierra de Gredos (Central Spain) through
time. A series of Landsat MSS images from 1975 to 1990, and a digital elevation model (DEM) were used to map fires, assess
topographical complexity and evaluate changes in landscape composition and structure. Functional regions across the entire
landscape were identified using different classification criteria (i.e., percentage burned area and topographic properties)
to model topographic and fire impacts at regional scales. A canonical variance partition method, with a time series split-plot
design, quantified the relative influence and co-variation of topography and fire on land cover patterns through time. Main
results indicated that analyzing portions of the landscape under similar environmental conditions and fire histories, the
effects of different fire regimes on the spatio-temporal dynamics of main land covers can be highlighted. However, the impact
of fire on landscape patterns was high variable among regions due to the different regeneration abilities of main land covers,
the topographic constraints and the fire histories of each region. Hence, broad patterns of fire related variance and co-variation
with topography emerged across the entire area due to the different conditions of each landscape portion in which this large
Mediterranean landscape was divided.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users. 相似文献