The pathology of spontaneous paratuberculosis in the North American bison (Bison bison)     

Buergelt CD  Layton AW  Ginn PE  Taylor M  King JM  Habecker PL  Mauldin E  Whitlock R  Rossiter C  Collins MT 《Veterinary pathology》2000,37(5):428-438

Gross and histopathologic examinations were performed on 70 North American bison (Bison bison) from a Mycobacterium avium paratuberculosis culture-positive herd. The bison examined were part of a breeding herd totaling 2,800 animals. Eight of 70 (11%) animals had gross findings of intestinal mucosal thickening, and 16 of 70 (23%) of the animals had enlarged mesenteric lymph nodes. Histologic lesions compatible with Johne's disease were diagnosed in 30 of 70 (43%) bison on the basis of the demonstration of noncaseating granulomatous inflammatory infiltrates and of one or more acid-fast bacilli characteristic of Mycobacterium avium paratuberculosis. A suspicious diagnosis of Johne's disease was obtained in 11 of 70 (16%) bison on the basis of the observation of noncaseating granulomatous inflammatory infiltrates without demonstrable acid-fast bacteria. Twenty-nine of 70 (41%) animals were assessed as histologically paratuberculosis free. Histologic results were compared to Johne's disease tests such as culture, serology, and polymerase chain reaction, which were performed on some of the cohort animals.  相似文献   

Expression of vascular endothelial growth factor in canine oral malignant melanoma     

K. H. Taylor  A. N. Smith  M. Higginbotham  D. D. Schwartz  D. M. Carpenter  E. M. Whitley 《Veterinary and comparative oncology》2007,5(4):208-218

Serum, plasma and tissue expression of vascular endothelial growth factor (VEGF) was measured in 20 dogs previously diagnosed histologically with oral melanoma. The concentrations of VEGF in serum and plasma were significantly higher in dogs with melanoma than in a control population (P ≤ 0.002). Concentrations of VEGF in the serum and plasma of dogs with melanoma were highly correlated (r = 0.867). Ninety‐five per cent of melanoma tissues expressed VEGF. Two staining patterns were detected: diffuse and granular cytoplasmic staining. High blood concentrations of VEGF were correlated to a shorter survival time in dogs receiving definitive therapy (P = 0.002). Survival times were significantly longer in dogs receiving definitive therapy versus palliative therapy (median 496 versus 97 days, P = 0.007). Blood concentrations of VEGF were associated with stage (P < 0.05). Dogs with oral melanoma have increased serum, plasma and tissue concentrations of VEGF. Increased expression of VEGF may be a reasonable target for future therapy of canine oral melanoma.  相似文献   

Comparison of carprofen and pethidine as postoperative analgesics in the cat     

T. V. Balmer    D. Irvine  R. S. Jones  †  M. J. Roberts  †  L. Sungsby  ‡  P. M. Taylor    A. E. Waterman  ‡ C. Waters  § 《The Journal of small animal practice》1998,39(4):158-164

The postoperative analgesia and sedation in cats given carprofen (4·0 mg/kg bodyweight by subcutaneous injection preoperatively) was compared to that in cats given pethidine (3·3 mg/kg bodyweight by intramuscular injection postoperatively) in a controlled, randomised, blinded, multicentre clinical trial. Further dosing with the particular analgesic was allowed if a cat was exhibiting unacceptable pain. In total, 57 carprofen cases and 59 pethidine cases were evaluated. Significantly fewer cats in the carprofen group required additional doses of analgesic, and mean pain scores were significantly lower from four hours after ovariohysterectomy, and at 18 to 24 hours after castration, compared to the pethidine group. In conclusion, carprofen provided as good a level of postoperative analgesia as pethidine, but of a longer duration (at least 24 hours) and was well tolerated. It thus provides an option for 'pre-emptive analgesia' in cats about to undergo surgery.  相似文献   

Recent advances in the diagnosis in livestock of Cryptosporidium, Toxoplasma, Giardia and other protozoa of veterinary importance     

M.A. Taylor  K.A. Webster 《Research in veterinary science》1998,65(3):183

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Hyperthyroidism Associated with a Thyroid Adenocarcinoma in a 21-Year-Old Gelding     

Sammy Ramirez  Jill J. McClure  Rustin M. Moore  Karen J. Wolfsheimer  Stephen D. Gaunt  Mustajab H. Mirza  Wayne Taylor 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1998,12(6):475-477

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The Urinary Excretion of Riboflavin by the Cat     

C. E. Waterhouse  T. Taylor  H. Partington 《The Journal of small animal practice》1964,5(2):161-165

Abstract— The daily riboflavin excretion of five adult cats has been studied for periods ranging from 7 to 11 days. The cats were housed in metabolism cages and were provided with a diet of cooked rabbit meat, wholemeal bread and water. The total amount of riboflavin excreted does not appear to be related to the dietary intake. The concentration of riboflavin in the urine does appear to be characteristic for a given cat under our experimental conditions.
Résumé— L'excrétion quotidienne de riboflavine chez cinq chats adultes a étéétudié pendant des périodes allant de 7 à 11 jours. Les chats étaient casés dans des cages à métabolisme et recevaient un régime de viande de lapin cuite, de pain entier et d'eau. La quantité totale de riboflavine excrétée ne semble pas être en rapport avec la quantité ingérée. Dans les conditions expérimentales que nous avons utilisées la concentration urinaire de riboflavine parait caractéristique pour un chat donné.
Zusammenfassung— In einer von 7 bis zu 11 Tagen reichenden Zeitspanne wurde untersucht, wieviel Laktoflavin fünf ausgewachsene Katzen täglich ausscheiden. Die Katzen wurden in Käfigen untergebracht, in denen der Stoffwechsel ständig überprüft werden kann, und sie wurden mit einer aus gekochtem Kaninchenfleisch, Vollkornbrot und Wasser bestehenden Diät gefüttert. Die Gesamt-menge des ausgeschiedenen Laktoflavins scheint in keiner Beziehung zu der Nahrungsaufnahme zu stehen. Die Konzentration des Laktoflavin im Urin scheint für eine unter unseren Versuchs-bedingungen stehende Katze charakteristisch zu sein.  相似文献   

Effects of the 1995–1997 drought on nitrate leaching in lowland England     

M.D. Morecroft  T.P. Burt  M.E. Taylor  A.P. Rowland 《Soil Use and Management》2000,16(2):117-123

Abstract. The effect of drought between summer 1995 and 1997 on stream and river nitrate concentrations was investigated using sites close to the long-running meteorological station in Oxford, UK. Nitrate concentrations in the River Windrush were relatively low during the drought, but after it had ended reached the highest level since records began in 1973. The low concentrations during the drought probably reflect a reduced contribution from agricultural runoff. High nitrate concentrations were found in a field drain at Wytham Environmental Change Network site during and after the drought, but discharge was greatly reduced. A woodland stream at Wytham had much lower nitrate concentrations than the field drain but these similarly increased during and after the drought. There was evidence that both a concentrating effect of low water volumes and enhanced soil nitrogen mineralization and nitrification rates were causing concentrations to rise. The effects of mineralization and nitrification were more important in woodland than agricultural land. Nitrate load over the course of a year was determined largely by discharge, but steeper gradients for the relationship between cumulative load and cumulative discharge were seen during and after the drought than before, reflecting the higher concentrations.  相似文献   

Gastric Neoplasia in Horses     

S.D. Taylor  G.J. Haldorson  B. Vaughan  N. Pusterla 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2009,23(5):1097-1102

Background: Gastric neoplasia of horses is incompletely described.
Objective: Provide history, clinical signs, and clinicopathological and pathological findings associated with gastric neoplasia in horses.
Animals: Twenty-four horses with gastric neoplasia.
Methods: Retrospective study. History, clinical signs, and clinicopathological and pathologic findings in horses diagnosed histologically with gastric neoplasia were reviewed.
Results: Horses ranged in age from 9 to 25 years (median 18 years at presentation). There was no apparent breed or sex predisposition. The most common presenting complaints were inappetance (17/24), weight loss (14/24), lethargy (7/24), hypersalivation (7/24), colic (5/24), and fever (5/24). The most consistent clinical signs were tachypnea (10/19), decreased borborygmi (8/19), and low body weight (7/17). Useful diagnostic tests included rectal examination, routine blood analysis, gastroscopy, abdominocentesis, and transabdominal ultrasound examination. Anemia was the most common hematologic abnormality encountered (7/19), and hypercalcemia of malignancy was seen in 4/16 horses. Squamous cell carcinoma was the most common tumor identified (19/24), and was most often (14/19) found as a single ulcerated, necrotic mass in the nonglandular portion of the stomach. Other gastric neoplasms encountered were leiomyoma (n=2), mesothelioma (n=1), adenocarcinoma (n=1), and lymphoma (n=1). Metastatic neoplasia was found in 18/23 horses. The median time from onset of clinical signs to death was 4 weeks, and all horses died or were euthanized because of gastric neoplasia.
Conclusions: Squamous cell carcinoma is the most common primary gastric neoplasia in horses. The survival time after diagnosis of gastric neoplasia in horses is short.  相似文献   

DISCUSSION     

Taylor WP 《Science (New York, N.Y.)》1930,71(1842):408-409

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Isolation of antigenic proteins from erythrocytes parasitised with Babesia divergens and a comparison of their immunising potential   总被引：1，自引：0，他引：1  

S M Taylor  C T Elliott  J Kenny 《Veterinary parasitology》1986,21(2):99-105

Soluble proteins present in the supernatant prepared from a sonicated lysate of concentrated erythrocytes infected with Babesia divergens were separated by isoelectric focussing into acidic and non acidic fractions. The acidic fraction was further separated by passage through Concanavalin A Sepharose (Con A) into two fractions, the first (Fraction 2) consisting of proteins plus one glycoprotein which did not bind to Con A, the second of glycoproteins (Fraction 1) which were eluted after binding to Con A. One group of six cows was treated with three injections of Fraction 2 with incomplete Freunds adjuvant (IFA); two other groups received the same number of injections of Fraction 1, one with IFA, the other with glucan as adjuvant. These cows plus an untreated control group were infected with 10(5) erythrocytes infected with a heterologous isolate of B. divergens. Only the group treated with Fraction 2 (Group 1) resisted lethal multiplication of the parasite. There were significant differences in magnitude of parasitaemia, reduction of packed cell volume and antibody titres between Group 1 and the other groups.  相似文献