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Leptospirosa pomona Abortion Storm in a Cattle Herd in Saskatchewan   总被引:2,自引:1,他引:1       下载免费PDF全文
Abortions occurred in 18% of 131 beef cows and heifers during two months, on a farm in southern Saskatchewan. The losses began two weeks after acute febrile illness and agalactia in a dairy cow to which the beef herd had been exposed. A diagnosis of Leptospira interrogans serovar pomona infection was made on the basis of serology in cows and the finding of leptospires in fetal tissues by fluorescent antibody test. Tentative diagnosis of infectious bovine rhinotracheitis delayed treatment and prophylaxis until infection attained high intensity in the herd and severe losses to the farmer occurred. Abortions ceased after vaccination against pomona and oxytetracycline treatment of pregnant cows, although chronic debility followed the acute phase of the disease in some cows. Recrudescence of infection was suspected four months later, when acute agalactia occurred in one cow and debility in calves and cows was recurring. Pomona infection was not proven, but dihydrostreptomycin treatment and revaccination were applied to the whole herd. Seroconversion and IgM antibody continued to indicate a persistent source of infection and susceptibility in a minority of the population one year after onset. The source of the original infection is believed to have been a carrier beef cow, or a dairy cow which was leptospiruric at the time of contact with the beef herd. With the exception of one aborted calf, no evidence of pomona infection was found outside the farm, in cattle or wild mammals tested serologically within a radius of 30 km, during one year following the outbreak.  相似文献   
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A ram lamb with congenital goitre showed signs of respiratory distress at birth. All previously affected lambs from this flock bad been born dead or bad died soon after birth. The serum free-thyroxine level at 1 birth was low (9.8 pmol/l) but treatment with oral L-thyroxine resulted in an increase in thyroxine blood levels to above normal and regression of the goitre. Four weeks after withdrawal of thyroid supplementation and when the lamb was eight weeks old, the radio iodide uptake mechanism of the thyroid glands was shown to be intact but the iodide was not organified. Low normal peroxidase activity was demonstrated in fresh thyroid tissue but gel electrophoresis demonstrated an absence of normal thyroglobulin from extracts of the goitrous thyroid. This lamb and the other affected lambs of this flock have an inherited defect in thyroglobulin synthesis and it is likely that the respiratory distress was associated with the low levels of thyroid hormone affecting foetal lung development.  相似文献   
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Three trials using 240 weanling pigs were conducted during winter months to determine the influence of nursery temperature ("comfortable" vs "cold") on the response of weanling pigs to added vitamin C (700 ppm) or E (55 IU/kg) to a corn-soybean meal diet. A "comfortable" temperature schedule (27 C initially with a weekly 2 C drop) was maintained in one nursery, with the temperature schedule in the "cold" nursery about 8 C lower. Plasma concentrations of vitamin C and vitamin E were elevated when the respective vitamins were added to the diet, but were not consistently influenced by nursery temperatures. Daily gain, daily feed intake and feed efficiency were not improved with the added C or E. Daily feed intake was increased and feed-to-gain ratios were larger for pigs housed in the "cold" nursery compared with pigs housed in the "comfortable" nursery; however, daily gains were similar in the two environments. Pigs housed in the "cold" nursery were slightly stressed, as indicated by heavier adrenal glands, but the antibody response and serum glucocorticoid concentrations were not significantly affected by either diet or temperature.  相似文献   
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