Board-invited review: the biology and regulation of preadipocytes and adipocytes in meat animals   总被引：2，自引：0，他引：2  

Hausman GJ  Dodson MV  Ajuwon K  Azain M  Barnes KM  Guan LL  Jiang Z  Poulos SP  Sainz RD  Smith S  Spurlock M  Novakofski J  Fernyhough ME  Bergen WG 《Journal of animal science》2009,87(4):1218-1246

The quality and value of the carcass in domestic meat animals are reflected in its protein and fat content. Preadipocytes and adipocytes are important in establishing the overall fatness of a carcass, as well as being the main contributors to the marbling component needed for consumer preference of meat products. Although some fat accumulation is essential, any excess fat that is deposited into adipose depots other than the marbling fraction is energetically unfavorable and reduces efficiency of production. Hence, this review is focused on current knowledge about the biology and regulation of the important cells of adipose tissue: preadipocytes and adipocytes.  相似文献   

The effect of photodynamic therapy on squamous cell carcinoma in a murine model: evaluation of time between intralesional injection to laser irradiation     

Barnes LD  Giuliano EA  Ota J  Cohn LA  Moore CP 《Veterinary journal (London, England : 1997)》2009,180(1):60-65

Successful treatment of naturally occurring periocular squamous cell carcinoma (SCC) in horses with photodynamic therapy (PDT) has been performed by injecting residual tumor with verteporfin and applying laser irradiation immediately following injection. This study used a murine model to evaluate the influence of time between intralesional injection of verteporfin to laser irradiation on tumor growth inhibition with PDT. Mice were randomized into six groups (n=10/group). Each tumor was injected with either 0.1mg/cm(3) of verteporfin (Tx) or 5% dextrose in water (C). Tx and C groups 1, 2, and 3 were irradiated at 1, 30, and 180min after injection. Wilcoxon-rank sum test (P< or =0.05) was performed to determine the relative change in tumor volume (RCTV) between groups. Statistical significance was demonstrated between treatment groups. Although verteporfin-PDT treated mice in Tx1 and Tx2 demonstrated a lower RCTV compared to C1 and C2 mice, the differences were not statistically significant.  相似文献   

Utility of high-density plantings in bay scallop, Argopecten irradians irradians, restoration     

Stephen T. Tettelbach  Debra Barnes  John Aldred  Gregg Rivara  Dennis Bonal  Andrew Weinstock  Chelsea Fitzsimons-Diaz  Josh Thiel  M. Chase Cammarota  Adam Stark  Katherine Wejnert  Richard Ames  John Carroll 《Aquaculture International》2011,19(4):715-739

Two different methods of establishing high-density spawner sanctuaries for bay scallop (Argopecten irradians irradians) restoration were evaluated over 2 years at a site in Northwest Harbor, East Hampton, New York, USA. Hatchery-reared scallops, which had been overwintered at nearby sites, were free-planted directly to the bottom in late March/early April at an initial target density of 94?C128 scallops/m². In addition, scallops were stocked in off-bottom culture units consisting of three vertically stacked 15-mm mesh ADPI^® bags at densities of 50, 100, or 200 scallops/bag (=117, 234, or 468 scallops/m²), respectively. Survival of scallops differed significantly by year, planting method, and scallop source. Survival of free-planted scallops was generally lower than caged scallops. Better survival of free-planted scallops in 2005 versus 2006 likely reflected the presence of luxuriant eelgrass beds in 2005, which were absent in 2006. Survival of scallops in ADPI bags was not appreciably related to stocking density. Shell growth was highest for free-planted scallops; in cages, growth was somewhat better at 50 versus 200 scallops/bag. Wet weights of epibionts were significantly higher in caged versus free-planted scallops. Reproductive condition of scallops stocked at 50/bag was usually higher than at 200/bag. Both free-planting and off-bottom systems yielded high densities of adult bay scallops at the time of spawning, which ensures a higher probability of successful fertilization of spawned eggs and thus a greater potential for success of restoration efforts.  相似文献