Mitral valve prolapse in 3-year-old healthy Cavalier King Charles Spaniels. An echocardiographic study.   总被引：2，自引：0，他引：2       下载免费PDF全文

H D Pedersen  B O Kristensen  K A Lorentzen  J Koch  A L Jensen    A Flagstad 《Canadian journal of veterinary research》1995,59(4):294-298

Clinical studies have shown that Cavalier King Charles Spaniels (CKCS) have a high prevalence of mitral valvular insufficiency (MVI). Echocardiography has the potential to disclose early valvular changes, and the present prospective study was designed to investigate the occurrence of mitral valve prolapse (MVP) in young CKCS without heart murmurs, and to correlate the degree of MVP with the clinical status of the dogs by including CKCS with MVI as well. The study was based on blinded evaluations of echocardiographic recordings of mitral valves from 34 CKCS and 30 control dogs. Thirteen (87%) of 15 three-year-old CKCS without heart murmurs had MVP (2 total and 11 partial), as compared with 1 (7%) of 15 three-year-old normal Beagle dogs (P < 0.0001), and none of 15 three-year-old normal Medium Size Poodles (P < 0.0001). Of 19 CKCS with MVI, MVP was found in 84% of the entire group and in 100% of dogs with pulmonary congestion or edema. The occurrence of total MVP tended to be higher in the group with MVI (47%, 9/19), when compared with the younger CKCS without heart murmurs (13%, 2/15, P = 0.06). MVP was positively associated with excessive heart rate variability (P = 0.003). The radius of curvature of the anterior mitral valve leaflet in systole was significantly reduced in dogs with MVP when compared with those without (P < 0.0001). In conclusion, this study shows that CKCS at an early age have a high occurrence of MVP. This suggests: 1) A genetic predisposition of CKCS to MVP; and 2) That MVP is a pathogenetic factor in the development of mitral valvular insufficiency. Follow up studies may add further support to these proposals, and clarify whether echocardiography may be an aid in selecting CKCS for future breeding.  相似文献   

The effect of vitamin E on the cell-mediated immune response in pigs     

M Jensen  C Fossum  M Ederoth  R V Hakkarainen 《Zentralblatt für Veterin?rmedizin. Reihe B. Journal of veterinary medicine. Series B》1988,35(7):549-555

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Comments on biocompatible osteoconductive polymer.     

G O Sertl  D J Jensen 《Journal of the American Veterinary Medical Association》1992,201(10):1489-1490

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Fish diseases of viral origin. A schematic review     

N J Jensen 《Nordisk veterinaermedicin》1978,30(4-5):217-220

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An outbreak of meningo-encephalitis in fallow deer caused by Listeria monocytogenes     

L Eriksen  H E Larsen  T Christiansen  M M Jensen  E Eriksen 《The Veterinary record》1988,122(12):274-276

An outbreak of listeric meningo-encephalitis occurred in a population of 1800 fallow deer (Dama dama) in a park during the winter and early spring of 1985 to 1986. Listeriosis was diagnosed in 41 of 42 fallow deer that showed the typical central nervous system signs of circling disease or were found dead. The diagnosis was verified by bacteriological examination of the brains of 35 animals. In five of the seven remaining cases listeriosis was diagnosed by histological examination, and in one animal by clinical signs alone. Listeria monocytogenes was isolated in three of 23 soil samples taken from the park. In addition, L monocytogenes was isolated from the intestinal contents of apparently normal fallow deer. Fifty isolates from animals and soil were serotyped and all of them belonged to serovar 4b except one from brain (serovar 1/2b) and three from intestinal contents (serovar 1/2a). In phage typing of 54 isolates, the 35 isolates from the brain and spleen of diseased animals belonged to the same lysovar, as did most isolates from other sources, but strains from intestinal contents belonged to three other phage types. No external source of L monocytogenes was demonstrated in the outbreak and stress due to the poor beech-mast crop, an increased stocking rate and a sudden change in the weather are suspected as predisposing factors.  相似文献   

Ammonia, pH and volatile fatty acids in the bovine rumen after feeding with hay.     

K Jensen 《Acta veterinaria Scandinavica》1975,16(2):258-268

The effect of feeding level and interval between feedings on the fermentation pattern in the bovine rumen have been investigated in experiments with hay. The animals were completely adapted heifers fitted with rumen cannulas, and the parameters measured were ammonia, pH, volatile fatty acids (VFA) and non-glucogenic/glucogenic ratio (NGGR) in the VFA mixture.Increasing feeding levels, ranging from 2/3 to 4/3 of maintenance level, resulted in higher average concentrations of VFA and lower pH in the rumen fluid. Further the highest level of intake caused a considerable diurnal variation in the pH and the concentration of total VFA, and increased the variation in the molar composition of the VFA mixture.Three feeding intervals ranging from 8 to 16 hrs., with hay administered at maintenance level, caused no changes in the fermentation pattern.Typical variations in the concentrations of ammonia and valeric acid as related to time after feeding were demonstrated, but the concentrations of the branched-chain fatty acids in the rumen fluid were found to be quite constant.It may be concluded that a representative mean value of the parameters measured, except for ammonia and valeric acid, may be based on relatively few samples when feed intake does not exceed maintenance level, whereas sampling every hour is required at higher feeding levels.  相似文献   

Role of predominant rumen bacteria in the cause of polioencephalomalacia (cerebrocortical necrosis) in cattle     

T R Haven  D R Caldwell  R Jensen 《American journal of veterinary research》1983,44(8):1451-1455

Rumen contents of 2 heifers with acute polioencephalomalacia (cerebrocortical necrosis) were compared with rumen contents from a healthy steer fed a fibrous diet. Also examined were (i) the quantitative nature of the predominant rumen microflora, (ii) the distribution of morphologic types of bacteria in the rumen contents, (iii) the extent that morphologic groups produced or degraded thiamine, and (iv) the cumulative effects of metabolic activities of the predominant rumen bacteria concerning the net production or degradation of thiamine. The differences in the frequency of occurrence of particular bacterial morphologic groups, the extent of growth, and the amount of thiamine metabolism in relationship to growth were also evaluated. The cumulative thiamine metabolism of the predominant bacteria associated with the rumen of polioencephalomalacia-affected heifers led to substantial net thiamine destruction, whereas metabolism associated with the rumen of a normal steer led to thiamine production. Polioencephalomalacia may occur as a consequence of alteration of the metabolic activities of the predominant resident ruminal bacteria associated with diseased cattle.  相似文献   

Phosphorus requirements of sows during gestation and lactation.     

B G Harmon  C T Liu  A H Jensen  D H Baker 《Journal of animal science》1975,40(4):660-664

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Glutathione Peroxidase Activity and Erythrocyte Lipid Peroxidation as Indices of Selenium and Vitamin E Status in Young Pigs     

P. Thode Jensen  V. Danielsen  H. E. Nielsen 《Acta veterinaria Scandinavica》1979,20(1):92

A randomized, blocked 2³ factorial experiment was conducted with 48 pigs from sows fed a diet low in selenium and vitamin E. From 3 to 12 weeks of age the piglets were kept in single pens and fed a basic diet consisting mostly of barley, dried skim milk, soybean meal and dried yeast, and containing 55 µg selenium and 3 mg vitamin E per kg. The treatment factors — i.e. feed supplements — were 2 levels of Se (nil, 60 µg/kg), 2 levels of vitamin E (nil, 50 mg/kg), and 2 levels of the feed antioxidant ethoxyquin (nil, 150 mg/kg). Blood samples, collected at termination of the experiment, were examined for glutathione peroxidase activity (GSH-Px) and resistance against erythrocyte lipid peroxidation (ELP) to evaluate Se and vitamin E status, respectively. Analysis of variance showed the GSH-Px activity to be litter-dependent (P < 0.001) and influenced by selenium supplementation (P < 0.001) but not by the other supplements or by interactions between supplements. Resistance against ELP was influenced only by vitamin E supplementation (P < 0.001). GSH-Px and ELP thus seem to be valuable and simple methods for evaluating, respectively, Se status and vitamin E status in growing pigs.  相似文献   

Muscular cysticercosis from Taenia ovis in feedlot lambs.     

R Jensen  R E Pierson  R D Schupbach 《Journal of the American Veterinary Medical Association》1975,167(8):742-745

From a Colorado enterprise annually fattening about 50,000 lambs, 3,664 animals were examined for muscular cysticercosis. Of the total number, 406 (11.1%) were parasitized, wheras an estimated 0.1% of Colorado lamb carcasses are infected. Of the infected lambs, 60% had cardiac lesions. Two types of cysticerci-viable and degenerated-were found. The lambs probably acquired infection from grazing summer ranges and pastures where coyotes or dogs infected with Taenia ovis contaminated the forage.  相似文献