Resistant starch for weaning pigs — Effect on concentration of short chain fatty acids in digesta and intestinal morphology     

Mette Skou Hedemann  Knud Erik Bach Knudsen 《Livestock Science》2007,108(1-3):175-177

We investigated the effect of potato starch, a source of resistant starch (RS), in diets for newly weaned pigs on production of short chain fatty acids (SCFA) and intestinal morphology. At weaning, at 4 weeks of age, 24 pigs were divided into 3 groups and fed diets containing 0 (C), 80 (P80) or 160 (P160) g raw potato starch per kg feed for 12 days. Pigs fed P160 had the longest villi whereas pigs fed P80 had the deepest crypts. Villous height at the mid-small intestine and average daily gain were positively correlated (r = 0.59, P < 0.01). The daily gain tended to be lower (P = 0.08) for pigs fed P80 than for pigs fed C or P160. The colon weight increased in pigs fed RS which coincided with an increased crypt depth in the colon. The concentration of SCFA increased in the large intestine with increasing amount of RS. The proportion of acetic acid decreased and the proportion of butyric acid increased in pigs fed P80 and P160. The increased SCFA production, especially of butyrate, may explain the colonic growth.  相似文献   

Effect of level of milk replacer fed to Holstein calves on performance during the preweaning period and starter digestibility at weaning   总被引：2，自引：1，他引：2  

M. Terr  M. Devant  A. Bach 《Livestock Science》2007,110(1-2):82-88

Calves following an enhanced-growth feeding program usually show lower starter intakes during the preweaning period compared with conventionally-fed calves. To assess whether this low intake in calves following an enhanced-growth feeding program affects calf capacity to digest starter after weaning, 19 Holstein male calves were used to measure apparent nutrient digestibility at weaning. Calves were divided in two groups: calves on a conventional feeding program (CF) and calves on an enhanced-growth feeding program (EF). After one week of adaptation to milk replacer (25% CP and 19% fat), the CF calves were fed 4 l/d of milk replacer (MR) at 12.5% DM dilution rate from d 1–28, and 2 l/d from d 29 to weaning day at d 35, and the EF calves were offered MR at 18% DM dilution rate: 4 l/d from d 1–6, 6 l/d from d 7–13, 7 l/d from d 14–20, 6 l/d from d 21–28, and 3 l/d from d 29 to 35. Calf starter (20% CP) was offered ad libitum from the beginning to the end of study at d 42, and its consumption was recorded daily. Calves were weighed at d 3, 17, 24, 31, 38 and 42. Daily total faeces collection was conducted for the last 5 d of study. Final BW was numerically greater in EF than in CF calves (88.6 vs 81.2 ± 3.36 kg, respectively). Starter DMI was greater (P < 0.05) in CF compared with EF calves during the preweaning (0.68 vs 0.36 ± 0.078 kg/d, respectively) and postweaning (2.52 vs 1.90 ± 0.102 kg/d, respectively) periods, but there were no differences in total DMI (1.12 and 1.26 ± 0.078 kg/d, in CF and EF calves, respectively) during the preweaning period. However, apparent DM, OM, NDF, CP, and GE digestibility coefficients were greater (P < 0.05) in CF compared with EF calves (77.4 vs 71.8 ± 1.23%, 78.7 vs 73.2 ± 1.18%, 34.7 vs 20.3 ± 3.79%, 77.1 vs 71.6 ± 1.29%, and 75.6 vs 69.8 ± 1.25%, respectively) the week after weaning. It is concluded that calves in the EF treatment presented lower nutrient digestibility coefficients compared with CF calves the week after weaning.  相似文献   

Advances in respiratory therapy.     

Elizabeth A Rozanski  Jonathan F Bach  Scott P Shaw 《Veterinary Clinics of North America: Small Animal Practice》2007,37(5):963-74, vii

Effective respiratory therapy depends on obtaining a definitive diagnosis and following established recommendations for treatment. Unfortunately, many respiratory conditions are idiopathic in origin or are attributable to nonspecific inflammation. In some situations, disorders are controlled rather than cured. Recent advances in pulmonary therapeutics include the use of new agents to treat common diseases and application of local delivery of drugs to enhance drug effect and minimize side effects.  相似文献   

Tasks and efficiency of breeding hygiene in the securing cattle reproduction     

S Bach  H Haase 《Monatshefte für Veterin?rmedizin》1972,27(10):387-392

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Observations on the diffusible calcium fraction in the serum of the cow during oestrus and during parturition   总被引：3，自引：0，他引：3  

S J Bach  A Messervy 《The Veterinary record》1969,84(9):210-213

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On the occurrence of a bone system disease in fattening bulls. I. Clinical and pathological-anatomic studies     

S Bach  H Haase 《Monatshefte für Veterin?rmedizin》1966,21(5):167-171

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Place de l'immunostimulation dans la therapeutique anti-infectieuse     

P Lesaver  J.F Bach 《Comparative immunology, microbiology and infectious diseases》1980,3(4)

An increasing number of substances is capable of potentiating immune responses. These can be grouped into several categories: bacterial products, leucocyte extracts (transfer factor, interferon) thymic hormones and synthetic drugs (levamisole). Their therapeutic use against infections is still uncommon for several reasons. First, the immunostimulants, particularly the bacterial extracts have many toxic side-effects. Second, most of them have not been obtained under pure and chemically-characterized form. Third the mechanisms of immunostimulation are not completely understood and depending on the route and the timing of injection, the immunostimulants can exhibit suppressive activities. For these reasons a larger use of immunostimulant substances requires purified or synthetic materials, careful experimental and clinical analysis of their effects and rigorous indications. These conditions are already fulfilled for some immunostimulants especially in immunodeficient virus-infected patients.  相似文献   

Management of a caseous lymphadenitis outbreak in a new Iberian ibex (Capra pyrenaica) stock reservoir     

Andreu Colom-Cadena  Roser Velarde  Jesús Salinas  Carmen Borge  Ignacio García-Bocanegra  Emmanuel Serrano  Diana Gassó  Ester Bach  Encarna Casas-Díaz  Jorge R López-Olvera  Santiago Lavín  Luís León-Vizcaíno  Gregorio Mentaberre 《Acta veterinaria Scandinavica》2014,56(1)

Background

In 2010, an Iberian ibex (Capra pyrenaica hispanica) stock reservoir was established for conservation purposes in north-eastern Spain. Eighteen ibexes were captured in the wild and housed in a 17 hectare enclosure. Once in captivity, a caseous lymphadenitis (CLA) outbreak occurred and ibex handlings were carried out at six-month intervals between 2010 and 2013 to perform health examinations and sampling. Treatment with a bacterin-based autovaccine and penicillin G benzatine was added during the third and subsequent handlings, when infection by Corynebacterium pseudotuberculosis was confirmed. Changes in lesion score, serum anti-C. pseudotuberculosis antibodies and haematological parameters were analyzed to assess captivity effects, disease emergence and treatment efficacy. Serum acute phase proteins (APP) Haptoglobin (Hp), Amyloid A (SAA) and Acid Soluble Glycoprotein (ASG) concentrations were also determined to evaluate their usefulness as indicators of clinical status.Once in captivity, 12 out of 14 ibexes (85.7%) seroconverted, preceding the emergence of clinical signs; moreover, TP, WBC, eosinophil and platelet cell counts increased while monocyte and basophil cell counts decreased. After treatment, casualties and fistulas disappeared and both packed cell volume (PCV) and haemoglobin concentration significantly increased. Hp, SAA and ASG values were under the limit of detection or showed no significant differences.

Conclusions

A role for captivity in contagion rate is suggested by the increase in antibody levels against C. pseudotuberculosis and the emergence of clinical signs. Although boosted by captivity, this is the first report of an outbreak of caseous lymphadenitis displaying high morbidity and mortality in wild ungulates. Treatment consisting of both vaccination and antibiotic therapy seemed to prevent mortality and alleviate disease severity, but was not reflected in the humoural response. Haematology and APP were not useful indicators in our study, perhaps due to the sampling frequency. Presumably endemic and irrelevant in the wild, this common disease of domestic small ruminants is complicating conservation efforts for the Iberian ibex in north-eastern Spain.  相似文献   

Bacterial Meningitis After Sinus Surgery in Five Adult Horses     

Fabienne S. Bach Med. Vet.  Jan M. Kuemmerle Dr. Med. Vet.  Diplomate ECVS  Edmund K. Hainisch Dr. Med. Vet.  Hubert Simhofer Dr. Med. Vet.  Diplomate EVDC Eq 《Veterinary surgery : VS》2014,43(6):697-703

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U1-specific protein C needed for efficient complex formation of U1 snRNP with a 5' splice site   总被引：18，自引：0，他引：18  

V Heinrichs  M Bach  G Winkelmann  R Lührmann 《Science (New York, N.Y.)》1990,247(4938):69-72

One of the functions of U1 small nuclear ribonucleoprotein (snRNP) in the splicing reaction of pre-mRNA molecules is the recognition of the 5' splice site. U1 snRNP proteins as well as base-pair interactions between U1 snRNA and the 5' splice site are important for the formation of the snRNP-pre-mRNA complex. To determine which proteins are needed for complex formation, the ability of U1 snRNPs gradually depleted of the U1-specific proteins C, A, and 70k to bind to an RNA molecule containing a 5' splice site sequence was studied in a nitrocellulose filter binding assay. The most significant effect was always observed when protein C was removed, either alone or together with other U1-specific proteins; the binding was reduced by 50 to 60%. Complementation of protein C-deficient U1 snRNPs with purified C protein restored their 5' splice site binding activity. These data suggest that protein C may potentiate the base-pair interaction between U1 RNA and the 5' splice site.  相似文献