Comparison of flow-mediated vasodilation in femoral and brachial arteries in healthy dogs     

Jones ID  Fuentes VL  Wrigglesworth D  Mort E  Elliott J 《American journal of veterinary research》2011,72(8):1029-1037

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Evaluation of subcutaneous and oral administration of robenacoxib and meloxicam for the treatment of acute pain and inflammation associated with orthopedic surgery in dogs     

Gruet P  Seewald W  King JN 《American journal of veterinary research》2011,72(2):184-193

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Survival and echocardiographic data in dogs with congestive heart failure caused by mitral valve disease and treated by multiple drugs: a retrospective study of 21 cases     

de Madron E  King JN  Strehlau G  White RV 《The Canadian veterinary journal. La revue veterinaire canadienne》2011,52(11):1219-1225

This retrospective study reports the survival time [onset of congestive heart failure (CHF) to death from any cause] of 21 dogs with mitral regurgitation (MR) and CHF treated with a combination of furosemide, angiotensin-converting enzyme inhibitor (ACEI, benazepril, or enalapril), pimobendan, spironolactone, and amlodipine. Baseline echocardiographic data: end-systolic and end-diastolic volume indices (ESVI and EDVI), left atrium to aorta ratio (LA/Ao), and regurgitant fraction (RF) are reported. Median survival time (MST) was 430 d. Initial dosage of furosemide (P = 0.0081) and LA/Ao (P = 0.042) were negatively associated with survival. Baseline echocardiographic indices (mean ± standard deviation) were 40.24 ± 16.76 for ESVI, 161.48 ± 44.49 mL/m(2) for EDVI, 2.11 ± 0.75 for LA/Ao, and 64.71 ± 16.85% for RF. Combining furosemide, ACEI, pimobendan, spironolactone, and amlodipine may result in long survival times in dogs with MR and CHF. Severity of MR at onset of CHF is at least moderate.  相似文献   

Online renewal of RCVS membership     

Holt J 《The Veterinary record》2011,168(19):520; discussion 520

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Single paracostal approach to thoracic duct and cisterna chyli: experimental study and case series     

Staiger BA  Stanley BJ  McAnulty JF 《Veterinary surgery : VS》2011,40(7):786-794

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Filaroides osleri (Oslerus osleri): two case reports and a review of canid infections in North America     

Yao C  O'Toole D  Driscoll M  McFarland W  Fox J  Cornish T  Jolley W 《Veterinary parasitology》2011,179(1-3):123-129

Infections of domesticated dogs by a worldwide parasitic nematode Filaroides osleri (Oslerus osleri) lead to verminous tracheobronchitis that are often misdiagnosed clinically as kennel cough, due to infection with the bacterium Bordetella bronchiseptica. Diagnosis of two canine cases in Wyoming, USA prompted a search of the literature of canid infections in North America. Infections of domestic dogs are reported in nine US states and four Canadian provinces. Dogs of multiple breeds and both sexes were infected. Most were two years old or younger at diagnosis. Anthelmintic treatments were effective in relieving clinical symptoms, as well as causing resolution of tracheobronchial nodules. Other canid species, including coyotes (Canis latrans) and wolves (Canis lupus), have been infected across North America with a prevalence of 23% and 4%, respectively. Infection with F. osleri should be included in the differential diagnosis of infectious tracheobronchitis of dogs. It can be confirmed most readily by endoscopic detection of distinctive submucosal parasite-filled nodules, combined with histological examination of endoscopic biopsies.  相似文献   

Evaluation of predictors for the diagnosis of hyperthyroidism in cats     

Wakeling J  Elliott J  Syme H 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2011,25(5):1057-1065

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Surveillance of avian influenza virus in migratory water birds in eastern Hokkaido, Japan     

Bui VN  Ogawa H  Karibe K  Matsuo K  Nguyen TH  Awad SS  Minoungou GL  Xininigen  Saito K  Watanabe Y  Runstadler JA  Happ GM  Imai K 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2011,73(2):209-215

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Using integrated population modelling to quantify the implications of multiple threatening processes for a rapidly declining population     

Jonathan R. Rhodes  Chooi Fei Ng  Deidré L. de Villiers  Harriet J. Preece  Clive A. McAlpine  Hugh P. Possingham 《Biological conservation》2011,(3):1081-1088

Many species of conservation concern are in decline due to threats from multiple sources. To quantify the conservation requirements of these species we need robust estimates of the impact of each threat on the rate of population decline. However, for the vast majority of species this information is lacking. Here we demonstrate the application of integrated population modelling as a means of deriving robust estimates of the impact of multiple threats for a rapidly declining koala (Phascolarctos cinereus) population in South-east Queensland, Australia. Integrated population modelling provides a basis for reducing uncertainty and bias by formally integrating information from multiple data sources into a single model. We quantify mortality rates due to threats from dog attacks, vehicle collisions and disease and the extent to which each of these mortality rates would need to be reduced, or how much habitat would need to be restored, to stop the population declining. We show that the integrated population modelling approach substantially reduces uncertainty. We also show that recovery actions that only address single threats would need to reduce those threats to implausibly low levels to recover the population. This indicates that strategies for simultaneously tackling multiple threats are necessary; a situation that is likely to be true for many of the world’s threatened species. This study provides an important framework for quantifying the conservation requirements of species undergoing declines due to multiple threats.  相似文献   

Avenanthramides are bioavailable and accumulate in hepatic, cardiac, and skeletal muscle tissue following oral gavage in rats     

Koenig RT  Dickman JR  Wise ML  Ji LL 《Journal of agricultural and food chemistry》2011,59(12):6438-6443

Avenanthramides (AVA), polyphenols found exclusively in oats ( Avena sativa L.), may play a role in the anti-inflammatory and antiatherogenic activity of oats. The bioavailability of AVA has been demonstrated previously, but its distribution at the organ and tissue level and the extent of conjugation following ingestion have been unexplored. Synthetic AVA was administered to 24 rats by oral gavage, whereas 6 control rats received saline. AVA concentrations were measured via HPLC in plasma, liver, heart, and gastrocnemius (GAS) obtained over a 12 h period (0, 2, 4, 12 h; n = 6 at each time point). Samples were extracted with and without glucuronidase-sulfatase to assess the level of conjugation. We conclude that AVA are bioavailable to the blood circulation following oral ingestion in the rat and reach peripheral tissues where they can be taken up by various organs differentially. With AVA remaining in the organs for up to 12 h, it seems possible to maintain an increased level of AVA in the rat via repeated feedings.  相似文献