Foot Rot of Ulluco Caused by Pythium aphanidermatum     

Keisuke TOMIOKA  Toyozo SATO  Tateo NAKANISHI 《Journal of General Plant Pathology》2002,68(2):189-190

Severe rot of stem bases caused by Pythium aphanidermatum was found on ulluco (Ullucus tuberosus) grown in Kagawa Prefecture, Japan, in September 1999. The name “foot rot of ulluco” is proposed for this new disease. Received 14 November 2001/ Accepted in revised form 7 January 2002  相似文献   

Dynamic left ventricular outflow tract obstruction secondary to hypovolemia in a German Shepard dog with splenic hemangiosarcoma     

Takuma AOKI  Hiroshi SUNAHARA  Keisuke SUGIMOTO  Tetsuro ITO  Eiichi KANAI  Sakurako NEO  Yoko FUJII  Yoshito WAKAO 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(9):1187-1190

Dynamic left ventricular outflow tract obstruction (DLVOTO) is a common condition in cats and humans. In this case report, a dog is described with DLVOTO secondary to severe intra-abdominal hemorrhage caused by a hemangiosarcoma. The dog was a 9-year-old, 35.7-kg, spayed female German Shepard dog that presented with a history of tachypnea and collapse. A Levine II/VI systolic murmur was present at the heart base. Abdominal ultrasonography revealed a splenic mass and a large amount of ascites. Echocardiography showed a reduced left ventricular diameter and an increased aortic velocity caused by systolic anterior motion (SAM) of the mitral valve apparatus. The heart murmur and the SAM were resolved after treatment including a splenectomy and a blood transfusion.  相似文献   

Critical limits of the degree of compactness and soil penetration resistance for the soybean crop in N Brazil   总被引：1，自引：0，他引：1       下载免费PDF全文

Pedro Daniel De Oliveira  Michel Keisuke Sato  Herdjania Veras de Lima  Sueli Rodrigues  Alvaro Pires da Silva 《植物养料与土壤学杂志》2016,179(1):78-87

In agricultural fields soil compaction is a major cause of physical degradation. Degree of compactness (DC) is a useful parameter for characterizing compaction and the response of crops for different soils. The objectives of this study were: (1) to identify the critical DC and PR values for soybean [Glycine max (L.) Merrill] using plant growth variables and (2) to verify the relationship between DC and PR, and assess which parameter is recommended for the evaluation of soil compaction. The study was conducted in a greenhouse in a completely randomized factorial design of 4 textures × 5 compaction levels for sandy loam and sandy clay loam soils, and 3 compaction levels for the clayey and very clayey soils. Soil samples were collected from the surface of a Xantic Kandiudox from the NE region of the State of Pará, Brazil. The DC was calculated from the maximum bulk density obtained by the Proctor test, and the PR curve was determined in undisturbed samples equilibrated in different matric potentials. The growth and development of the soybean was favored in the DC range of 80 to 85%, regardless of soil texture. The critical degree of compactness for the growth of soybean was around 98% regardless of soil texture, while the critical values for penetration resistance at field capacity varied according to soil texture and bulk density and were 28.2, 5.6, 3.5, and 5.2 MPa for the sandy loam, sand clay loam, clayey and very clayey soils, respectively. The root length was the plant growth variable most susceptible to soil compaction. Change in soil penetration resistance was poorly related with change in degree of compactness showing that one parameter cannot be replaced by the other. Because PR is quickly determined in field and have a direct relationship with plant growth, for the soils evaluated in this study we recommend the use of soil PR to assess the state of soil compaction.  相似文献   

Microwave and steam injection drying of CO2 laser incised Sugi lumber     

Tomy Listyanto  Keisuke Ando  Hidefumi Yamauchi  Nobuaki Hattori 《Journal of Wood Science》2013,59(4):282-289

To investigate the effect of CO₂ laser incising under five drying methods on drying characteristics of Sugi lumber, the squares (120 mm × 120 mm) of Sugi lumber with length of 650 mm were used. A half of samples were incised by CO₂ laser with incising density of 2,500 holes/m². Five types of drying methods were used: microwave drying, steam injection drying, and three combinations of microwave heating and steam injection drying. Steam injection drying was conducted by injecting superheated steam of 120 °C through a perforated plate heated to 140 °C of an injection press. Microwave was irradiated with the power of 3 kW at frequency of 2.45 GHz. The results indicated that incising helps heat through a specimen and thus the whole temperature raised rapidly, which was up to threefolds compared to that of no-incised one. Incised specimens dried by a combination of microwave heating for 1 h and steam injection showed the highest drying rate, which was up to 5.3 %/h. Incising and microwave heating contributed positively to dry lumber under more uniform distribution of moisture content and to reduce surface and internal checks. Incised specimen dried by microwave showed the most uniform distribution of moisture content without surface and internal checks.  相似文献   

PML regulates apoptosis at endoplasmic reticulum by modulating calcium release     

Giorgi C  Ito K  Lin HK  Santangelo C  Wieckowski MR  Lebiedzinska M  Bononi A  Bonora M  Duszynski J  Bernardi R  Rizzuto R  Tacchetti C  Pinton P  Pandolfi PP 《Science (New York, N.Y.)》2010,330(6008):1247-1251

The promyelocytic leukemia (PML) tumor suppressor is a pleiotropic modulator of apoptosis. However, the molecular basis for such a diverse proapoptotic role is currently unknown. We show that extranuclear Pml was specifically enriched at the endoplasmic reticulum (ER) and at the mitochondria-associated membranes, signaling domains involved in ER-to-mitochondria calcium ion (Ca(2+)) transport and in induction of apoptosis. We found Pml in complexes of large molecular size with the inositol 1,4,5-trisphosphate receptor (IP(3)R), protein kinase Akt, and protein phosphatase 2a (PP2a). Pml was essential for Akt- and PP2a-dependent modulation of IP(3)R phosphorylation and in turn for IP(3)R-mediated Ca(2+) release from ER. Our findings provide a mechanistic explanation for the pleiotropic role of Pml in apoptosis and identify a pharmacological target for the modulation of Ca(2+) signals.  相似文献   

Decreased apoptotic polymorphonuclear leukocyte rate in dogs with pyometra   总被引：1，自引：0，他引：1  

Sano J  Oguma K  Kano R  Tsumagari S  Hasegawa A 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2004,66(1):103-105

Polymorphonuclear neutrophil (PMN) apoptosis was examined in three dogs with pyometra by TUNEL assay in a 24-hr incubation period and compared with that in healthy control dogs (n=5). The incidence of apoptotic PMNs in dogs with pyometra was 26.4 +/- 5% and that in healthy dogs was 54.3 +/- 7%. The results indicated that apoptotic PMN rates in dogs with pyometra were significantly lower than those in control dogs (p<0.05), suggesting the prolongation of PMN survival.  相似文献   

Molecular cloning of canine thrombomodulin cDNA and expression in normal tissues     

Maruyama H  Oguma K  Maeda S  Kano R  Tsujimoto H  Watari T  Tokuriki M  Hasegawa A 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2004,66(11):1423-1427

Thrombomodulin (TM) is a glycoprotein localized mainly on endothelial cell surfaces, and is a major regulator of vascular thromboresistance. The entire open reading frame of canine TM cDNA comprises 1737 bp, encoding 578 amino acid residues. Comparison of the deduced amino acid sequence from canine TM with those of human, mouse, rat, rabbit and bovine (partial) TM sequences revealed 73.1%, 69.1%, 65.8%, 74.3% and 69.5% identity, respectively. Canine TM mRNA expression was confirmed by RT-PCR analysis in lung, liver, spleen, kidney, pancreas and lymph node, and was relatively low in heart, cerebrum, urinary bladder and uterus. The present results provide valuable data for research into canine coagulation disorders.  相似文献   

Impact of fungal drug transporters on fungicide sensitivity, multidrug resistance and virulence     

de Waard MA  Andrade AC  Hayashi K  Schoonbeek HJ  Stergiopoulos I  Zwiers LH 《Pest management science》2006,62(3):195-207

Drug transporters are membrane proteins that provide protection for organisms against natural toxic products and fungicides. In plant pathogens, drug transporters function in baseline sensitivity to fungicides, multidrug resistance (MDR) and virulence on host plants. This paper describes drug transporters of the filamentous fungi Aspergillus nidulans (Eidam) Winter, Botrytis cinerea Pers and Mycosphaerella graminicola (Fückel) Schroter that function in fungicide sensitivity and resistance. The fungi possess ATP-binding cassette (ABC) drug transporters that mediate MDR to fungicides in laboratory mutants. Similar mutants are not pronounced in field resistance to most classes of fungicide but may play a role in resistance to azoles. MDR may also explain historical cases of resistance to aromatic hydrocarbon fungicides and dodine. In clinical situations, MDR development in Candida albicans (Robin) Berkhout mediated by ABC transporters in patients suffering from candidiasis is common after prolonged treatment with azoles. Factors that can explain this striking difference between agricultural and clinical situations are discussed. Attention is also paid to the risk of MDR development in plant pathogens in the future. Finally, the paper describes the impact of fungal drug transporters on drug discovery.  相似文献   

Contraceptive effect of a gonadotropin-releasing hormone vaccine on a captive female African Lion (Panthera leo): a case study     

Keisuke KAWASE  Jumpei TOMIYASU  Kazuyuki BAN  Ryosuke ONO  Satoshi ANDO  Aya ONO  Ran KIMURA  Kanako TOMISAWA  Motozumi MATSUI  Shun-ichi SHIIHARA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(9):1454

Lions (Panthera leo) breed well under captivity, so contraception has been commonly conducted for population management, leading to a demand for a less invasive and reversible contraceptive approach in lions. In this study, we examined the efficacy of a commercial gonadotropin-releasing hormone vaccine as a method of suppressing reproductive activity in a sexually matured female lion. Under behavioral restraint, the vaccine was injected twice (days 0 and 109). After the initial vaccination, ovarian activity is still observed. After the second vaccination, contraceptive effect was confirmed for 246 days until restart of estrous cycles. We confirmed only a slight swelling around the injection site after the second vaccination. This study may suggest an alternative option for a contraceptive method in lions.  相似文献   

Heritability estimates for wood stiffness and its related near-infrared spectral bands in sugi (Cryptomeria japonica) clones     

Takaaki Fujimoto  Keisuke Chiyoda  Kazuho Yamaguchi  Keiya Isoda 《Journal of Forest Research》2015,20(1):206-212

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