Ecosystem service supply and vulnerability to global change in Europe   总被引：12，自引：0，他引：12  

Schröter D  Cramer W  Leemans R  Prentice IC  Araújo MB  Arnell NW  Bondeau A  Bugmann H  Carter TR  Gracia CA  de la Vega-Leinert AC  Erhard M  Ewert F  Glendining M  House JI  Kankaanpää S  Klein RJ  Lavorel S  Lindner M  Metzger MJ  Meyer J  Mitchell TD  Reginster I  Rounsevell M  Sabaté S  Sitch S  Smith B  Smith J  Smith P  Sykes MT  Thonicke K  Thuiller W  Tuck G  Zaehle S  Zierl B 《Science (New York, N.Y.)》2005,310(5752):1333-1337

Global change will alter the supply of ecosystem services that are vital for human well-being. To investigate ecosystem service supply during the 21st century, we used a range of ecosystem models and scenarios of climate and land-use change to conduct a Europe-wide assessment. Large changes in climate and land use typically resulted in large changes in ecosystem service supply. Some of these trends may be positive (for example, increases in forest area and productivity) or offer opportunities (for example, "surplus land" for agricultural extensification and bioenergy production). However, many changes increase vulnerability as a result of a decreasing supply of ecosystem services (for example, declining soil fertility, declining water availability, increasing risk of forest fires), especially in the Mediterranean and mountain regions.  相似文献   

Sulphated glycosaminoglycans and proteoglycans in the developing vertebral column of juvenile Atlantic salmon (Salmo salar)     

Kirsten O. Hannesson  Elisabeth Ytteborg  Harald Takle  Grethe Enersen  Grete Bæverfjord  Mona E. Pedersen 《Fish physiology and biochemistry》2015,41(4):1029-1051

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The brokerage role of small states and territories in global corporate networks     

Kirsten Martinus  Thomas Sigler  Iacopo Iacopini  Ben Derudder 《Growth and change》2021,52(1):12-28

Global economic activity is networked through cross‐national linkages between firm headquarters, branches, and subsidiaries. Brokerage emerges as a key territorial function of this network, with some places acting as gateways or intermediaries for flows of global knowledge, information, or trade. This function is particularly salient for small states and territories leveraging the benefits of borrowed size by offering global professional services, warehousing, logistics, shipping, and finance to wealthy nations or high net individuals. Nonetheless, to date our understanding of how small states and territories facilitate wealth accumulation is limited to broad concepts of their role as “gateways” or “brokers.” Drawing on a typology of brokerage and a network analysis applied to the ties between approximately 700,000 firm headquarter and subsidiary locations of 13 of the world's largest stock exchanges, we explore the brokerage role of small states and territories through case studies of Luxembourg, Singapore, Hong Kong, and Panama. Brokerage is found to play an important role in the economy of all four. We argue that each of these small states and territories is uniquely positioned as a broker in global corporate networks, but that this role differs according to geo‐economic and political positionality.  相似文献   

CCNU in the treatment of canine epitheliotropic lymphoma     

Williams LE  Rassnick KM  Power HT  Lana SE  Morrison-Collister KE  Hansen K  Johnson JL 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2006,20(1):136-143

This retrospective study examined the use of CCNU (1-[2-chloroethyl]3-cyclohexyl-1-nitrosurea) in 36 dogs with epitheliotropic lymphoma. Thirty-one (86%) dogs had the cutaneous form of disease, and 5 (14%) dogs had the oral form of disease. Nineteen (51%) dogs were treated with other chemotherapeutic agents before receiving CCNU. All dogs had detectable disease at the time CCNU therapy was initiated. Dogs received a median starting CCNU dosage of 70 mg/m2 (range, 50-100 mg/m2). The median number of treatments administered was 3 (range, 1-12 treatments). After the initial treatment, the CCNU dosage was adjusted in 9 of 26 (35%) dogs in which CCNU was continued: 7 had dosage reductions, and 2 had dosage escalations. Twenty-eight of 36 (78%) dogs had a measurable response to CCNU for a median duration of 106 days (95% confidence interval [CI], 75-182). Six dogs (17%) had a complete response, including 5 dogs with the cutaneous form and 1 dog with the oral form. Twenty-two dogs (61%) had a partial response, including 20 dogs with the cutaneous form and 2 dogs with the oral form, for a median duration of 88 days (95% CI, 62-170). Toxicoses after CCNU chemotherapy included myelosuppression in up to 29% of the dogs, gastrointestinal signs in up to 22% of the dogs, and liver enzyme activity increases in up to 86% of the dogs. This study demonstrates that CCNU chemotherapy can be considered a reasonable option for the treatment of canine epitheliotropic lymphoma in dogs.  相似文献   

Effect of antivenin dose on outcome from crotalid envenomation: 218 dogs (1988–2006)     

Jennifer L. McCown DVM  DACVIM  Kirsten L. Cooke DVM  DACVIM  Rita M. Hanel DVM  DACVIM  DACVECC  Galin L. Jones BS  MStat  PhD 《Journal of Veterinary Emergency and Critical Care》2009,19(6):603-610

Objective – To determine whether the dose of antivenin administered is associated with a difference in survival of crotalid‐envenomated dogs. A secondary objective was to determine whether other covariables affect survival. Design – Retrospective study (1988–2006). Setting – Private referral center and university small animal teaching hospital. Animals – Two hundred and eighteen dogs with evidence of crotalid envenomation and treatment with equine‐derived antivenin. Interventions – Administration of antivenin. Measurements and Main Results – Patient signalment, physical and clinicopathologic data at time of presentation, treatments, complications of antivenin therapy, length and cost of hospitalization, and outcome were recorded. Confidence intervals were determined for the difference in median number of vials administered and for median dosage for patients that lived versus died. Penalized logistic regression was performed to evaluate the effect of other covariables on survival. The median age of affected dogs was 3 years (range 6 w–12 y) with a median weight of 25.7 kg (range 1.95–86.4 kg). The median number of antivenin vials administered was 1.0 (range 1.0–10.0). Acute and chronic reactions were reported in 7% (16/218) and 0.9% (2/218) of dogs, respectively. Nine of 218 dogs (4.1%) died. The median number of vials administered to the nonsurvivors and survivors were 2.0 (range 1–5 vials) and 1.0 (range 1–10 vials), respectively. The median number of vials received was significantly different in dogs that died versus those that lived (P<0.05). Increased heart rate (P=0.02) and petechiation (P=0.04) were associated with decreased likelihood of survival, while diphenhydramine (P=0.02) and fluoroquinolone (P=0.046) administration was associated with increased likelihood of survival. The median duration of hospitalization was 1.0 day (range 2 h–22 d). The median cost of hospitalization was US$1592.00 (range US$267.20–US$6738.00). Conclusion – The administration of more vials of antivenin is potentially associated with negative outcome; however, a causal relationship has not been established. Controlled, prospective studies are needed to optimize antivenin administration.  相似文献   

Long-term monitoring of tropical bats for anthropogenic impact assessment: Gauging the statistical power to detect population change     

Christoph F.J. Meyer  Ludmilla M.S. Aguiar  Julio Baumgarten  Jean-François Cosson  Jakob Fahr  Neil Furey  Robert Hodgkison  Kirsten G. Jung  Thomas H. Kunz  Isabel Moya  Paul A. Racey  Erica M. Sampaio  Christian C. Voigt  Christa D. Weise 《Biological conservation》2010,143(11):2797-2807

Bats are ecologically important mammals in tropical ecosystems; however, their populations face numerous environmental threats related to climate change, habitat loss, fragmentation, hunting, and emerging diseases. Thus, there is a pressing need to develop and implement large-scale networks to monitor trends in bat populations over extended time periods. Using data from a range of Neotropical and Paleotropical bat assemblages, we assessed the ability for long-term monitoring programs to reliably detect temporal trends in species abundance. We explored the magnitude of within-site temporal variation in abundance and evaluated the statistical power of a suite of different sampling designs for several different bat species and ensembles. Despite pronounced temporal variation in abundance of most tropical bat species, power simulations suggest that long-term monitoring programs (?20 years) can detect population trends of 5% per year or more with adequate statistical power (?0.9). However, shorter monitoring programs (?10 years) have insufficient power for trend detection. Overall, our analyses demonstrate that a monitoring program extending over 20 years with four surveys conducted biennially on five plots per monitoring site would have the potential for detecting a 5% annual change in abundance for a suite of bat species from different ensembles. The likelihood of reaching adequate statistical power was sensitive to initial species abundance and the magnitude of count variation, stressing that only the most abundant species in an assemblage and those with generally low variation in abundance should be considered for detailed population monitoring.  相似文献   

Response of <Emphasis Type="Italic">Sorghum bicolor</Emphasis> varieties to soil salinity for feed and food production in Karakalpakstan,Uzbekistan     

Tamara Begdullayeva  Kirsten M. Kienzler  Elena Kan  Nazar Ibragimov  John P. A. Lamers 《Irrigation and Drainage Systems》2007,21(3-4):237-250

Water and land salinization, caused by ill-practiced irrigation and drainage is acute and widespread in Karakalpakstan, Uzbekistan. A crop frequently grown in these marginal areas is sorghum because of its capability to adapt to saline conditions. However, the salt uptake potential of local varieties for salt-ameliorative purposes, as well as possible income-generation benefits, have not yet been studied. Therefore, field experiments on low, medium and highly saline soils were conducted using four sorghum cultivars (S. vulgare, S. cernuum, S. durra, and S. technicum). The effect of soil salinity on biomass, stover and grain yield, the baking and feed quality, and total water soluble salt (TDS) accumulation, was assessed according to varieties, plant fractions and growth phases. Results showed that S. cernuum had the highest grain yield on the low (5.13 t ha⁻¹), medium (6.05 t ha⁻¹) and highly (3.3 t ha⁻¹) saline soil. S. technicum showed the lowest growth potential under all salinity levels. TDS accumulation varied between 406 and 185 kg ha⁻¹ depending on variety, site, plant fractions and growth stage. Irrespective of the soil salinity levels and varieties, TDS was highest in stover and leaves, while highest TDS uptake, mainly chlorides and bicarbonates, occurred between booting and flowering. Baking quality of all varieties was extremely low, whereas the in-vitro feed was assessed as of medium quality. The findings indicate the scope of local sorghum varieties for phytomelioration of marginal lands in Karakalpakstan, while concurrently satisfying a wider range of rural livelihood needs.  相似文献   

Impact of the health and living conditions of migrant and non-migrant Senegalese adolescent girls on their nutritional status and growth     

Garnier D  Simondon KB  Hoarau T  Benefice E 《Public health nutrition》2003,6(6):535-547

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Identification and in vitro biological activities of hop proanthocyanidins: inhibition of nNOS activity and scavenging of reactive nitrogen species     

Stevens JF  Miranda CL  Wolthers KR  Schimerlik M  Deinzer ML  Buhler DR 《Journal of agricultural and food chemistry》2002,50(12):3435-3443

Oligomeric proanthocyanidins constitute a group of water-soluble polyphenolic tannins that are present in the female inflorescences (up to 5% dry wt) of the hop plant (Humulus lupulus). Humans are exposed to hop proanthocyanidins through consumption of beer. Proanthocyanidins from hops were characterized for their chemical structure and their in vitro biological activities. Chemically, they consist mainly of oligomeric catechins ranging from dimers to octamers, with minor amounts of catechin oligomers containing one or two gallocatechin units. The chemical structures of four procyanidin dimers (B1, B2, B3, and B4) and one trimer, epicatechin-(4beta-->8)-catechin-(4alpha-->8)-catechin (TR), were elucidated using mass spectrometry, NMR spectroscopy, and chemical degradation. When tested as a mixture, the hop oligomeric proanthocyanidins (PC) were found to be potent inhibitors of neuronal nitric oxide synthase (nNOS) activity. Among the oligomers tested, procyanidin B2 was most inhibitory against nNOS activity. Procyanidin B3, catechin, and epicatechin were noninhibitory against nNOS activity. PC and the individual oligomers were all strong inhibitors of 3-morpholinosydnonimine (SIN-1)-induced oxidation of LDL, with procyanidin B3 showing the highest antioxidant activity at 0.1 microg/mL. The catechin trimer (TR) exhibited antioxidant activity more than 1 order of magnitude greater than that of alpha-tocopherol or ascorbic acid on a molar basis.  相似文献   

Inhibitory effects of feeding with carrots or (-)-falcarinol on development of azoxymethane-induced preneoplastic lesions in the rat colon   总被引：3，自引：0，他引：3  

Kobaek-Larsen M  Christensen LP  Vach W  Ritskes-Hoitinga J  Brandt K 《Journal of agricultural and food chemistry》2005,53(5):1823-1827

The effects of intake of dietary amounts of carrot or corresponding amounts of (-)-(3R)-falcarinol from carrots on development of azoxymethane (AOM)-induced colon preneoplastic lesions were examined in male BDIX rats. Three groups of eight AOM-treated rats were fed the standard rat feed Altromin supplemented with either 10% (w/w) freeze-dried carrots with a natural content of 35 mug falcarinol/g, 10% maize starch to which was added 35 mug falcarinol/g purified from carrots, or 10% maize starch (control). After 18 weeks, the animals were euthanized and the colon was examined for tumors and aberrant crypt foci (ACF), which were classified into four size classes. Although the number of small ACF was unaffected by the feeding treatments, the numbers of lesions as a function of increasing size class decreased significantly in the rats that received one of the two experimental treatments, as compared with the control treatment. This indicates that the dietary treatments with carrot and falcarinol delayed or retarded the development of large ACF and tumors. The present study provides a new perspective on the known epidemiological associations between high intake of carrots and reduced incidence of cancers.  相似文献