Acute cortisol responses of calves to four methods of dehorning by amputation     

SP SYLVESTER  KJ STAFFORD  DJ MELLOR  RA BRUCE  RN WARD 《Australian veterinary journal》1998,76(2):123-126

Objective To measure the plasma cortisol response in calves dehorned by four different methods (scoop, guillotine shears, saw, embryotomy wire) for 9 h after dehorning.
Design A physiological study with controls.
Procedure Horn amputation was carried out on calves restrained manually in a race.
Results The four methods of dehorning provoked similarly increased cortisol responses which lasted for 6 h. During the first hour after dehorning the plasma cortisol concentrations were similar to those following ACTH injection. The overall cortisol response to control handling was about 30% of the responses to dehorning.
Conclusions The similarity of the cortisol responses produced by the four methods of dehorning suggests that the distress experienced by calves following dehorning by amputation is similar regardless of method used.  相似文献   

Walker unveils r&d strategy     

Lawler A 《Science (New York, N.Y.)》1994,266(5193):1938

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NSF Takes Leap Into School Reform     

Lawler A 《Science (New York, N.Y.)》1994,266(5193):1936-1938

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Science and technology policy headed for political maelstrom     

Lawler A 《Science (New York, N.Y.)》1994,266(5188):1152-1153

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White House Ponders Increase for DOE Labs     

Lawler A 《Science (New York, N.Y.)》1994,266(5187):963-964

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Book review, Integrated Public Lands Management: A Coarse-Scale Economic Perspective     

Joshua Lawler 《Landscape Ecology》2003,18(2):207-208

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Adsorptive effects of di-tri-octahedral smectite on Clostridium perfringens alpha, beta, and beta-2 exotoxins and equine colostral antibodies     

Lawler JB  Hassel DM  Magnuson RJ  Hill AE  McCue PM  Traub-Dargatz JL 《American journal of veterinary research》2008,69(2):233-239

OBJECTIVE: To determine the adsorptive capability of di-tri-octahedral smectite (DTOS) on Clostridium perfringens alpha, beta, and beta-2 exotoxins and equine colostral antibodies. SAMPLE POPULATION: 3 C perfringens exotoxins and 9 colostral samples. PROCEDURES: Alpha, beta, and beta-2 exotoxins were individually co-incubated with serial dilutions of DTOS or bismuth subsalicylate, and the amount of toxin remaining after incubation was determined via toxin-specific ELISAs. Colostral samples from healthy mares were individually co-incubated with serial dilutions of DTOS, and colostral IgG concentrations were determined via single radial immunodiffusion assay. RESULTS: Di-tri-octahedral smectite decreased the amount of each C perfringens exotoxin in co-incubated samples in a dose-dependent manner and was more effective than bismuth subsalicylate at reducing exotoxins in vitro. Decreases in the concentration of IgG were detected in samples of colostrum that were combined with DTOS at 1:4 through 1:16 dilutions, whereas no significant decrease was evident with DTOS at the 1:32 dilution. CONCLUSIONS AND CLINICAL RELEVANCE: Di-tri-octahedral smectite effectively adsorbed C perfringens exotoxins in vitro and had a dose-dependent effect on the availability of equine colostral antibodies. Results suggested that DTOS may be an appropriate adjunctive treatment in the management of neonatal clostridiosis in horses. In vivo studies are necessary to fully assess the clinical efficacy of DTOS treatment.  相似文献   

Evidence for Genetic Involvement in Feline Dilated Cardiomyopathy     

Dennis F. Lawler DVM    AIan J. Templeton PhD  Katherine L. Monti PhD 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1993,7(6):383-387

Quantitative genetic evaluation of clinical dilated cardiomyopathy (DCM) was conducted in a large cattery with known history. Data showed that clinically affected cats were significantly more interrelated than randomly chosen case-control populations from the same colony. The results of this study suggest that quantitative inheritance, either interactive with or independent of nutrition or presently unknown factors, is involved in feline dilated cardiomyopathy. (Journal of Veterinary Internal Medicine 1993; 7:383–387. Copyright © 1993 by the American College of Veterinary Internal Medicine.)  相似文献   

Visualizing science. New imaging tools put the art back into science     

Lawler A 《Science (New York, N.Y.)》2001,292(5519):1044-1047

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Archaeology. Heavy damage feared after Taliban decree     

Lawler A 《Science (New York, N.Y.)》2001,291(5510):1873-1875

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