Treatment of Animal Toxicoses: A Regulatory Perspective     

Susan J. Bright DVM  Michael J. Murphy DVM  JD  PhD  Janice C. Steinschneider MA  JD  Randall A. Lovell DVM  PhD  Lynn O. Post DVM  PhD  CAPT  USPHS 《Veterinary Clinics of North America: Food Animal Practice》2011,27(2):481-512

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Risk factors associated with the occurrence of swine dysentery in Western Australia: results of a postal survey     

ID ROBERTSON  JRL MHOMA  DJ HAMPSON 《Australian veterinary journal》1992,69(4):92-93

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Resistance of Fasciola hepatica to triclabendazole   总被引：1，自引：0，他引：1  

DJ OVEREND  FL BOWEN 《Australian veterinary journal》1995,72(7):275-276

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Preulcerative changes to the pars oesophagea associated with Torulopsis glabrata infection in a weaned pig     

DJ. McGILLIVERY 《Australian veterinary journal》1989,66(10):337-338

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The characteristics and causes of sheep losses in the Victorian Mallee     

DJ HARRIS  G. NOWARA† 《Australian veterinary journal》1995,72(9):331-340

SUMMARY The extent and causes of sheep losses in the semi-arid Mallee region of north-western Victoria were assessed by interviewing the owners of 79 randomly selected farms running 241 flocks in 1987/88 and 245 flocks in 1988/89. Mean annual losses were higher in ram flocks (21%) than in ewe flocks (7%), in flocks of non-Merino sheep (rams 24%, ewes 11%, weaners 5%) than in Merino (rams 11%, ewes 6%, wethers 4%, weaners 4%) and in ewe flocks 3 or more years old (10%) than in young ewe flocks (3.5%). In flocks where losses exceeded 5%, the causes most often reported by farmers were blowfly strike (especially in Merino sheep and weaners), ewe losses in autumn close to lambing, and heliotrope (Heliotropium europaeum) poisoning. Heliotrope poisoning was considered by the authors to be the main reason for the higher losses in old ewes than in young ewes and in non-Merino sheep than in Merino sheep. Losses of ewes associated with pregnancy and lambing were considered by the authors to be often predisposed by liver damage caused by heliotrope poisoning, and high losses in non-Merino ram flocks were attributed to both heliotrope poisoning and their ability to escape through boundary fences. Reasons for continuing high losses due to enterotoxaemia are discussed. Losses due to gastro-intestinal parasites, footrot and foot abscess were low.  相似文献   

Immunisation of laying hens against Salmonella enteritidis with live attenuated vaccines   总被引：3，自引：0，他引：3  

P A Barrow  M A Lovell  A Berchieri 《The Veterinary record》1990,126(10):241-242

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Ivermectin and piperazine toxicoses in dogs and cats   总被引：1，自引：0，他引：1  

R A Lovell 《Veterinary Clinics of North America: Small Animal Practice》1990,20(2):453-468

Review of all reports involving anthelmintics in dogs and cats to the IAPIC between January 1, 1986 and August 10, 1988, revealed that ivermectin (extra-label use) and piperazine accounted for over 50% of the calls assessed as toxicoses and suspected toxicoses. Both ivermectin and piperazine are gamma-aminobutyric acid (GABA) agonists and their major effects appear to be on the central nervous system. Ivermectin toxicoses at estimated doses of greater than or equal to 100-less than 500 micrograms/kg were reported more than once only in the collies (n = 25) and Australian shepherds (n = 10); these two breeds accounted for 46% (69 of 150) of the toxicoses and suspected toxicoses calls in dogs. Ataxia, behavioral disturbances, tremors, mydriasis, weakness/recumbency, apparent blindness, hypersalivation/drooling (dogs only), and coma were the most commonly reported clinical signs in dogs and cats with suspected ivermectin toxicoses. Shock, dyspnea, vomiting, and ataxia were the most common clinical signs attributed to the microfilaricidal activity of ivermectin. Piperazine was the anthelmintic with the greatest number of reports of toxicoses and suspected toxicoses in cats. Piperazine neurotoxicity in cats and dogs usually was manifested by muscle tremors, ataxia, and/or behavioral disturbances within 24 hours after estimated daily dose(s) between 20 and 110 mg/kg.  相似文献   

Failure to detect antibody to turkey rhinotracheitis virus in Australian poultry flocks     

IG BELL  DJ ALEXANDER 《Australian veterinary journal》1990,67(6):232-233

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The effects of antigenic competition on the efficacy of multivalent footrot vaccines     

CL SCHWARTZKOFF  JR EGERTON†  DJ STEWART‡  PR LEHRBACH§  TC ELLEMAN¶  PA HOYNE¶ 《Australian veterinary journal》1993,70(4):123-126

SUMMARY A multivalent footrot vaccine has been developed, containing pilus antigens produced in recombinant Pseudomonas aeruginosa and representing all nine serogroups of Dichelobacter (Bacteroides) nodosus commonly recognised in the field. The responses of sheep to the multivalent vaccine have been compared with those to monovalent vaccines representing only a single serogroup. Antigenie competition between serogroups occurred in sheep immunised with the multivalent formulation, but high levels of protection were still achieved. The study showed that in multivalent footrot vaccines, antigenic competition is predominantly due to the presence of a family of immunologically-related pilus antigens rather than to interference by extraneous proteins.  相似文献   

Immunological detection of cardiac glycosides in plants     

DJ RADFORD  K. CHEUNG  R. URECH  JR GOLLOGLY  P. DUFFY 《Australian veterinary journal》1994,71(8):236-238

Summary Australian native and introduced plants were examined, using digoxin immunoassays, to detect the presence of cross-reacting cardiac glycosides. These compounds were found in 27 species from 20 genera. The assay technique can also be used on serum samples to confirm cardiac glycoside ingestion.  相似文献