MRI ischemic and hemorrhagic lesions in arterial and venous territories characterize central nervous system intravascular lymphoma in dogs     

Chiara Mattei  Anna Oevermann  Daniela Schweizer  Julien Guevar  Thomas W. Maddox  Kathryn L. Fleming  Emanuele Ricci  Marco Rosati  Roberta Biserni  John F. Griffin IV  Angie Rupp  Rodrigo Gutierrez-Quintana  Isabelle Masseau  Kimberly M. Newkirk  Silke Hecht  Swan Specchi 《Veterinary radiology & ultrasound》2023,64(2):294-305

Intravascular lymphoma (IVL) is characterized by the proliferation of large malignant lymphocytes within the lumen of blood vessels. This retrospective, multi-center, case series study aimed to describe the MRI features of confirmed central nervous system IVL in dogs and compare them with histopathological findings. Medical record databases from seven veterinary centers were searched for cases of histologically confirmed IVL. Dogs were included if an MRI was performed. The MRI studies and histopathology samples were reviewed to compare the MRI changes with the histopathological findings. Twelve dogs met the inclusion criteria (12 brains and three spinal cords). Imaging of the brains revealed multifocal T2-weighted/FLAIR hyperintense and T1-weighted iso-hypointense lesions, with variable contrast enhancement; areas of abnormal diffusion both in arterial and venous territories in diffusion-weighted imaging; and meningeal enhancement. On gradient echo images (GRE), the changes comprised tubular susceptibility artifacts, consistent with the “susceptibility vessel sign”, and additional variably sized/shaped intraparenchymal susceptibility artifacts. Spinal cord lesions presented as fusiform T2-weighted hyperintensities with scattered susceptibility artifacts on GRE and variable parenchymal and meningeal contrast enhancement. On histopathology, subarachnoid hemorrhages and neuroparenchymal areas of edema and necrosis, with or without hemorrhage, indicating ischemic and hemorrhagic infarctions, were found. These lesions were concurrent with severely dilated meningeal and parenchymal arteries and veins plugged by neoplastic lymphocytes and fibrin. Due to the unique angiocentric distribution of IVL, ischemic and hemorrhagic infarcts of variable chronicity affecting both the arterial and venous territories associated with thrombi formation can be detected on MRI.  相似文献   

Characterization of irrigator emitter to be used as solid set canopy delivery system: which is best for which role in the vineyard?     

Eric Mozzanini  Marco Grella  Paolo Marucco  Paolo Balsari  Fabrizio Gioelli 《Pest management science》2023,79(2):584-597

Background

The timely and flexible treatment of solid set canopy delivery systems (SSCDS) is expanding. Laboratory and field trials were conducted to evaluate the performance of three different irrigators (Pulsar™ system and nozzle combination), typically used in anti-frost and irrigation in vineyards/apple orchards, for plant protection product (PPP) delivery in a Guyot-trained trellised vineyard.

Results

Results showed that irrigator setups perform best when matched to the task—flat fan emitters for horizontal spray application (canopy top) and circular emitters for middle and low canopy application. A combination configuration of a double-sided flat fan and circular emitter system was indicated as the best option for homogenous coverage and minimal ground losses.

Conclusion

The tested emitters hold promise for SSCDS delivery of PPPs in vineyards. Further validation of the alternative use of this technology is warranted. © 2022 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.  相似文献   

Antibody titres against canine papillomavirus 1 peak around clinical regression in naturally occurring oral papillomatosis          下载免费PDF全文

Arda Sancak  Claude Favrot  Marco D. Geisseler  Martin Müller  Christian E. Lange 《Veterinary dermatology》2015,26(1):57-e20

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Role of Embryonic and Maternal Genotype on Prenatal Survival and Foetal Growth in Rabbit          下载免费PDF全文

C Naturil‐Alfonso  F Marco‐Jiménez  E Jiménez‐Trigos  MD Saenz‐de‐Juano  MP Viudes‐de‐Castro  R Lavara  JS Vicente 《Reproduction in domestic animals》2015,50(2):312-320

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What is the definition of intraoperative hypotension in dogs? Results from a survey of diplomates of the ACVAA and ECVAA          下载免费PDF全文

Marco Ruffato  Lorenzo Novello  Louise Clark 《Veterinary anaesthesia and analgesia》2015,42(1):55-64

ObjectiveDetermine arterial blood pressure range that diplomates of the American College of Veterinary Anesthesia and Analgesia (ACVAA) and European College of Veterinary Anaesthesia and Analgesia (ECVAA) use to define intraoperative hypotension in dogs and identify the threshold values used for intervention.Study designSurvey of veterinary anesthesia specialists.PopulationDiplomates of the ACVAA and ECVAA.MethodsACVAA and ECVAA diplomates (n=313) were invited to participate in an Internet-based survey regarding anesthetized healthy dogs undergoing two types of procedures (diagnostic or surgical).ResultsThere were 151 respondents to the survey; 70.2% were ACVAA diplomates and 29.8% were ECVAA diplomates. The majority of the respondents (70.9%) worked in academia while the others were in private practice (19.2%), or research, diagnostic or pharmaceutical fields (9.9%). Hypotension was defined (mean ± SD) by the respondents as systolic arterial blood pressure (SAP) <87 ± 8 mmHg for surgical cases and <87 ± 6 mmHg for diagnostic cases, or mean arterial pressure (MAP) <62 ± 4 mmHg for both types of cases. Arterial pressures reported to prompt treatment were SAP 85 ± 13 mmHg or MAP 61 ± 4 mmHg in surgical cases, and SAP 84 ± 11 mmHg or MAP 63 ± 8 mmHg in diagnostic cases.Conclusions and clinical relevanceThere was agreement between ACVAA and ECVAA diplomates on the definition of intraoperative hypotension in dogs during anesthesia. The blood pressures used to define hypotension were similar to the pressures that would prompt diplomates to start treatment. Readers could infer that diplomates define hypotension as a clinical condition that requires treatment at the time of diagnosis.  相似文献   

The use of contrast‐enhanced ultrasonography for the detection of active renal hemorrhage in a dog with spontaneous kidney rupture resulting in hemoperitoneum          下载免费PDF全文

Gian Marco Gerboni DVM  Giulia Capra DVM  Silvia Ferro DVM  Claudio Bellino DVM  PhD  Manuela Perego DVM  Stefania Zanet DVM  Antonio D'Angelo DVM  PhD  Paola Gianella DVM  PhD  DACVIM 《Journal of Veterinary Emergency and Critical Care》2015,25(6):751-758

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Variation in nitrogen supply changes water-use efficiency of Pseudotsuga menziesii and Populus x euroamericana; a comparison of three approaches to determine water-use efficiency     

Ripullone F  Lauteri M  Grassi G  Amato M  Borghetti M 《Tree physiology》2004,24(6):671-679

We studied the effects of three nitrogen (N) supply rates (low, intermediate and high) on Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco) seedlings and poplar clone "I-214" (Populus x euroamericana (Dole) Guinier) cuttings growing in mini-stands. Our specific objectives were to: (1) evaluate the effects of N supply on water-use efficiency (WUE) and biomass production; (2) determine if N affects WUE through control of carbon assimilation rates or through stomatal control of water loss; and (3) compare three methods of estimating WUE: one short-term method (WUE(i), based on gas exchange measurements) and two long-term methods (WUE(T), based on the ratio between biomass production and transpired water, and Delta, based on leaf carbon isotope discrimination tested as a proxy of WUE). In both species, biomass production, WUE(i) and WUE(T) increased with increasing N supply, but there was no effect of N supply on either transpiration or stomatal conductance and Delta was negatively related to leaf N concentration. Plots of Delta versus both WUE(i) and WUE(T) revealed negative trends, but the regression between WUE(i) and Delta was significant only for Douglas-fir, and the regression between WUE(T) and Delta was significant only for poplar. Thus, the mechanisms underlying the response of WUE to N supply were mainly related to a positive effect of N supply on photosynthetic rates. The data confirm that carbon isotope discrimination may be a useful proxy of WUE. The finding that N availability enhances both biomass production and WUE may have practical implications in regions where these factors impose constraints on forest productivity.  相似文献   

The new European legislation on traditional herbal medicines: main features and perspectives     

Silano M  De Vincenzi M  De Vincenzi A  Silano V 《Fitoterapia》2004,75(2):107-116

Under the Italian Presidency of the Council of the European Union (July 2003-December 2003) an agreement has been reached by the European Parliament and the Council on the approval of the proposal of Directive of the European Parliament and the Council amending the Directive 2001/83/EC as regards traditional herbal medicinal products. Once implemented in the E.U. Member States, this new Directive will remove the constraints that have made it difficult granting marketing authorisations of herbal substances and preparations as traditional medicinal products under the pre-existing Community legislation. The main features (i.e. traditional herbal medicine definition, simplified registration procedure, provisions for Community herbal monographs and Community list of herbal substances and preparations and establishment of the Committee for Herbal Medicinal Products) of this new Community legislation are analysed and discussed in the present paper together with some expected positive public health impacts.  相似文献   

Identification and analysis of single nucleotide polymorphisms (SNPs) in citrus   总被引：1，自引：0，他引：1  

Valdenice Moreira Novelli  Marco Aurélio Takita  Marcos Antonio Machado 《Euphytica》2004,138(3):227-237

Most of the cultivated species of citrus have narrow genetic basis. Relationships among species and cultivars are obscured by sexual compatibility, polyembryony, apomixis and a high incidence of somatic mutations. DNA analysis is crucial in genetic studies not only for citrus breeding programs but also for characterization of hybrids and species. In this paper, single nucleotide polymorphisms (SNPs) were investigated in 58 accessions of Citrus, hybrids and related genera. Genomic sequences of Pêra IAC sweet orange (Citrus sinensis L. Osbeck) were used for primer design and selection of sequence tagged sites (STSs) for identification of SNPs. Analysis of 36 STSs showed identical sequences among 40 of the 41 sweet orange accessions studied. However, these accessions were heterozygous for many SNPs. Ten selected STSs were analyzed in 17 additional accessions from 13 species and hybrids. Comparing to the Pêra IAC sweet orange accession, a total of 150 polymorphic nucleotides were identified and most of the alterations were transitions (52.7%). The greatest number of SNPs was observed in Poncirus trifoliata (L.) Raf. and the smallest in Ponkan mandarin (Citrus reticulata Blanco). At the intra-specific level, Baía Gigante (Citrus sinensis L. Osbeck) was the only sweet orange accession with a divergent SNPs genotype, which corroborates the hypothesis of a hybrid origin for this accession. Although the STSs analyzed represent randomly sampled genomic sequences, they provided consistent information about the level of polymorphism and showed the potential of SNPs markers for characterization and phylogenetic studies.  相似文献   

: a software to evaluate model performance     

Gianni Fila  Gianni Bellocchi  Marco Acutis  Marcello Donatelli   《European Journal of Agronomy》2003,18(3-4):369

The software (Integrated Resources for Evaluating Numerical Estimates) is a data analysis tool designed to provide easy access to statistical techniques for use in model evaluation. Mostly, non-replicated model estimates (E_i) are compared against non-replicated measurements (M_i). The software also allows comparing individual estimates against replicated measurements (or vice versa) and replicated estimates against replicated measurements. The evaluation of model performance is essentially based on the difference E_i−M_i, or on the correlation–regression of E_i vs. M_i (or vice versa). In addition, model evaluation by probability distributions, pattern analysis, or fuzzy-based aggregation statistics is allowed. Graphics are included in most analytical tasks. The results are displayed in separate spreadsheets and can be exported into MS Excel workbooks.  相似文献