Penalized regression techniques for modeling relationships between metabolites and tomato taste attributes     

Patricia Menéndez  Paul Eilers  Yury Tikunov  Arnaud Bovy  Fred van Eeuwijk 《Euphytica》2012,183(3):379-387

The search for models which link tomato taste attributes to their metabolic profiling, is a main challenge within the breeding programs that aim to enhance tomato flavor. In this paper, we compared such models calculated by the traditional statistical approach, stepwise regression, with models obtained by the new generation of regression techniques, known as penalized regression or regularization methods. In addition, for penalized regression, different scenarios and various model selection criteria were discussed to conclude that classical crossvalidation, selects models with many superfluous variables whereas model selection criteria such as Bayesian information criterion, seem to be more suitable, when the goal is to find parsimonious models, to explain tomato taste attributes based on metabolic information. An exhaustive comparison of the discussed methodology was done for six sensory traits, showing that the most important covariates were identified by the stepwise regression as well as by some of the penalized regression methods, despite the general disagreement on the size of the regression coefficients between them. In particular, for stepwise regression the coefficients are inflated due to their high variance which is not the case with penalized regression, showing that this new methodology, can be an alternative to obtain more accurate models.  相似文献   

Comparison of field portable XRF and aqua regia/ICPAES soil analysis and evaluation of soil moisture influence on FPXRF results     

Arnaud Robin Schneider  Benjamin Cancès  Clément Breton  Marie Ponthieu  Xavier Morvan  Alexandra Conreux  Béatrice Marin 《Journal of Soils and Sediments》2016,16(2):438-448

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Preparation of antibodies and development of an enzyme-linked immunosorbent assay for determination of dealkylated hydroxytriazines   总被引：3，自引：0，他引：3  

Sanvicens N  Pichon V  Hennion MC  Marco MP 《Journal of agricultural and food chemistry》2003,51(1):156-164

The development of an indirect competitive enzyme-linked immunosorbent assay (ELISA) for dealkylated hydroxytriazines is reported here for the first time. The assay uses polyclonal antibodies raised against N-(4-amine-6-hydroxy-[1,3,5]triazin-2-yl)-4-aminobutanoic acid (hapten 2g) conjugated to keyhole limpet hemocyanin by the active ester method. The immunizing hapten was synthesized by first introducing the amino group to the triazine ring in a protected form in order to increase its solubility in organic media. Subsequent steps consisted of reacting this compound with an appropriate spacer arm, followed by removal of the protecting group in acidic media. The resulting assay uses a homologous competitor hapten coupled to conalbumin by the mixed anhydride method. Coating antigens prepared using a homologous covalent coupling procedure failed to produce competitive immunoassays. The assay tolerates media with high ionic strength (up to 70 mS cm(-)(1)) and basic pH values (7.5-9.5 units). Under the optimized conditions, this ELISA is specific for dealkylated hydroxytriazines, reaching suitable limits of detection.  相似文献   

Dermatophytosis due to Microsporum persicolor: a retrospective study of 16 cases     

Muller A  Guaguère E  Degorce-Rubiales F  Bourdoiseau G 《The Canadian veterinary journal. La revue veterinaire canadienne》2011,52(4):385-388

A retrospective study of 16 cases of dermatophytosis due to Microsporum persicolor in dogs is reported. Hunting dogs were overrepresented (12/16). Skin lesions were observed on the face in all cases, but also on other locations (limbs, neck). The lesions included alopecia (15/16), erythema (13/16), scales (14/16), and crusts (13/16). Histopathology was performed in 10 cases and showed folliculitis and a lichenoid interface dermatitis. Fungal culture was positive in all cases and clinical resolution was achieved with standard antifungal agents (enilconazole, ketoconazole, griseofulvin). Two recurrences were observed (new contacts with rodents).  相似文献   

Transcatheter glue arterial embolization of a mass in the hind limb of a dog     

de La Villeon G  Louvet A  Behr L  Borenstein N 《The Canadian veterinary journal. La revue veterinaire canadienne》2011,52(3):289-294

This article reports the use of transarterial glue embolization in the treatment of a soft-tissue mass in the hind limb of a dog that was referred for a > 15-cm diameter soft tissue mass in the caudal thigh. Clinical improvement showed that the percutaneous therapeutic cyanoacrylate glue embolization procedure was technically feasible and useful.  相似文献   

Effects on the aphid parasitoid <Emphasis Type="BoldItalic">Aphidius ervi</Emphasis> of an insecticide (Plenum<Superscript>®</Superscript>, pymetrozine) specific to plant-sucking insects     

Jean-Rener Joseph  Arnaud Ameline  Aude Couty 《Phytoparasitica》2011,39(1):35-41

The use of a selective insecticide is highly recommended for Integrated Pest Management programs. Plenum (a.i.: pymetrozine; Syngenta Agro), a systemic insecticide, is regarded as a good candidate for use in situations where plant-sucking insects have to be controlled and where natural enemies can play a substantial role as biological control agents. In this context, the effects of Plenum on a host–endoparasitoid relationship were investigated. Potato aphids Macrosiphum euphorbiae were reared for 4 days on an artificial diet supplemented with a low concentration of Plenum (sublethal concentration inducing 15% aphid mortality) before parasitization by the endoparasitoid Aphidius ervi. The development of A. ervi larvae was negatively affected, especially during the early stages of development, and the sex ratio of the progeny was strongly male-biased. Moreover, the host-choice experiment showed that A. ervi was not able to discriminate between control and Plenum-contaminated aphids. These results show that Plenum may not be as selective as it was previously thought to be, and the observed effects need to be considered when developing IPM systems.  相似文献   

Response of sediment biofilm to increased dissolved organic carbon supply in groundwater artificially recharged with stormwater   总被引：1，自引：0，他引：1  

Arnaud Foulquier  Florian Mermillod-Blondin  Florian Malard  Janine Gibert 《Journal of Soils and Sediments》2011,11(2):382-393

Purpose  

Best management practices encompass diverse artificial groundwater recharge (AGR) systems that heavily rely upon the capacity of the soil and vadose zone to retain large quantities of organic matter generated during stormwater runoff on urban catchments. However, the supply of stormwater-derived dissolved organic carbon (DOC) at the water-table region of aquifers can enhance the rate of biogeochemical processes by fueling heterotrophic microbial metabolism. This study examined changes in the abundance and activity of sediment biofilm in response to increased DOC supply at the water table of an urban aquifer intentionally recharged with stormwater. Changes in microbial abundance and activity under field conditions were compared with those measured in laboratory slow filtration columns supplied with an easily biodegradable source of DOC.  相似文献   

Serum parathyroid hormone in X-linked hypophosphatemia   总被引：6，自引：0，他引：6  

C Arnaud  F Glorieux  C Scriver 《Science (New York, N.Y.)》1971,173(999):845-847

Serum immunoreactive parathyroid hormone(IPTH) is normal in patients with X-linked hypophosphatemic rickets who are not treated with phosphate salts. Phosphate raises IPTH in these patients. Endogenous IPTH does not influence the existing defect in tubular reabsorption of phosphate in male patients.  相似文献   

The global atmospheric circulation on moist isentropes   总被引：1，自引：0，他引：1  

Pauluis O  Czaja A  Korty R 《Science (New York, N.Y.)》2008,321(5892):1075-1078

The global atmospheric circulation transports energy from the equatorial regions to higher latitudes through a poleward flow of high-energy and -entropy parcels and an equatorward flow of air with lower energy and entropy content. Because of its turbulent nature, this circulation can only be described in some averaged sense. Here, we show that the total mass transport by the circulation is twice as large when averaged on moist isentropes than when averaged on dry isentropes. The additional mass transport on moist isentropes corresponds to a poleward flow of warm moist air near Earth's surface that rises into the upper troposphere within mid-latitudes and accounts for up to half of the air in the upper troposphere in polar regions.  相似文献   

Multiple transatlantic introductions of the western corn rootworm     

Miller N  Estoup A  Toepfer S  Bourguet D  Lapchin L  Derridj S  Kim KS  Reynaud P  Furlan L  Guillemaud T 《Science (New York, N.Y.)》2005,310(5750):992

The invasion of Europe by the western corn rootworm, North America's most destructive corn pest, is ongoing and represents a serious threat to European agriculture. Because this pest was initially introduced in Central Europe, it was believed that subsequent outbreaks in Western Europe originated from this area. Using model-based Bayesian analyses of the genetic variability of the western corn rootworm, we demonstrate that this belief is false: There have been at least three independent introductions from North America during the past two decades. This result raises questions about changing circumstances that have enabled a sudden burst of transatlantic introductions.  相似文献