Arthroscopic verification of ultrasonographic diagnosis of meniscal pathology in dogs   总被引：1，自引：0，他引：1  

Mahn MM  Cook JL  Cook CR  Balke MT 《Veterinary surgery : VS》2005,34(4):318-323

OBJECTIVE: To determine the clinical usefulness of ultrasonography for diagnosis of meniscal pathology in dogs. STUDY DESIGN: Double-blind prospective study. ANIMALS: Dogs (n=10) with lameness localized to the stifle. MATERIALS AND METHODS: Sonographic examination of each affected stifle was performed by 1 ultrasonographer unaware of specific historical and clinical data for the dog. Sonographic findings were recorded, but not reviewed until study completion. Arthroscopic examination of the affected stifle was performed within 48 hours of ultrasonography by 1 surgeon unaware of ultrasonographic findings. Arthroscopic findings were recorded, but not reviewed until study completion. Two investigators compared the ultrasonographic and arthroscopic findings at study completion to determine the sensitivity, specificity, positive predictive value, and negative predictive value. RESULTS: Two of the 10 dogs had bilateral stifle evaluation. Twenty-four lateral and medial menisci, with normal and abnormal findings, were examined. The sensitivity and specificity for ultrasonographic diagnosis were 90.0% and 92.9%, respectively; positive and negative predictive values were 90.0% and 92.9%, respectively. CONCLUSIONS: Ultrasonography is highly specific and sensitive for diagnosing bucket handle tears of the medial meniscus in dogs. CLINICAL RELEVANCE: Ultrasonographic evaluation of menisci in dogs is a noninvasive method for accurately and efficiently diagnosing pathology, determining the need for surgical intervention, and providing comprehensive information to clients.  相似文献   

Foreign body attachment to polypropylene suture material extruded into the small intestinal lumen after enteric closure in three dogs     

Milovancev M  Weisman DL  Palmisano MP 《Journal of the American Veterinary Medical Association》2004,225(11):1713-5, 1701

Three dogs in which polypropylene suture material was used to close an enteric surgery site in a continuous pattern were evaluated at a later date because of recurrence of signs of intestinal disease. Surgery in each dog revealed that the suture material had been extruded into the lumen of the intestine and acted as a site for attachment of a foreign body. The nonabsorbable nature of polypropylene and its use in a continuous pattern are possible explanations for this complication. Polydioxanone or poliglecaprone 25 may be suitable alternatives to polypropylene for use in a continuous pattern for closure of small intestinal surgery sites.  相似文献   

Markers of bone metabolism in dog breeds of different size     

Breur GJ  Allen MJ  Carlson SJ  Richardson DC 《Research in veterinary science》2004,76(1):53-55

Serum and urinary markers of bone turnover may be of value in animals as noninvasive tools for determining the response of the skeleton to disease and injury. Although normal values for bone markers have been reported for the Beagle, concerns remain that breed to breed differences will complicate the interpretation of bone marker data in dogs. To explore this, we examined serum bone markers in two breeds of vastly different size, Pomeranians and Irish Wolfhounds. Our hypothesis was that serum concentrations of bone markers are similar in toy and giant dog breeds and fall within the same range as those reported for Beagles. Bone alkaline phosphatase (BALP) and carboxy-terminal telopeptide of type I collagen (ICTP), respectively markers of bone formation and bone resorption, were measured in age matched Pomeranians (n=14) and Irish Wolfhounds (n=14). No statistically significant differences between the mean BALP and mean ICTP serum concentrations from Pomeranians and Irish Wolfhounds were found. All BALP and ICTP concentrations were within the reference range reported for Beagles. The results of this study suggest that serum BALP and ICTP concentrations in giant and toy breeds are the same as in Beagles and that these assays may be used for dogs of all sizes.  相似文献   

Echocardiography in the chinchilla     

Linde A  Summerfield NJ  Johnston M  Melgarejo T  Keffer A  Ivey E 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2004,18(5):772-774

Heart disease has been described in the chinchilla and, with increasing popularity as a pet, the demand for diagnostic evaluation and treatment has increased. The goal of this study was to determine reference values for echocardiographic measurements in chinchillas and the effect of anesthesia on these measurements. Seventeen clinically healthy adult chinchillas were studied. All animals were anesthetized with isoflurane by mask. Standard echocardiographic views were used. A difference was seen in the echocardiographic measurements for left ventricular systolic dimension, fractional shortening, aortic (Ao) diameter, left atrial (LA) diameter, ratio of LA diameter to Ao diameter, and peak flow velocities and ejection times for Ao and pulmonary artery flows between awake and anesthetized chinchillas.  相似文献   

Myosin heavy chain profiles and body composition are different in old versus young Standardbred mares   总被引：2，自引：0，他引：2  

Lehnhard RA  McKeever KH  Kearns CF  Beekley MD 《Veterinary journal (London, England : 1997)》2004,167(1):59-66

There are limited data on age-related changes in body composition or skeletal muscle in the horse. Therefore, the purpose of this study was to investigate any differences in muscle myosin heavy chain (MHC) and body composition associated with aging. Twenty-three young (4-8 years) and eight old (20+ years) unfit Standardbred mares were evaluated. Rump fat thickness was measured using B-mode ultrasound and per cent body fat (% fat) was calculated. Needle muscle biopsies were obtained from right gluteus medius muscle. MHC composition was determined via sodium dodecyl sulphate-polyacrylamide gel electrophoresis. Three MHC isoforms were subsequently identified as type I, type IIA, and type IIX and quantified using a scanning and densometric system. There were no significant differences (p>0.05) between old and young mares in fat (%) (19.0+/-6.4 vs 20.5+/-5.4), fat mass (kg) (102.3+/-39.9 vs 106.9+/-37.1), or body weight (kg) (529.4+/-34.9 vs 512.7+/-57.7). However, the old mares had significantly (p<0.05) greater lean body mass than the young mares (427.1+/-24.5 vs 405.7+/-37.9). Aged mares had significantly (p<0.05) less type I (7.8+/-2.9% vs 12.1+/-4.4%) and IIA (27.8+/-7.1% vs 36.1+/-9.5%) fibres than the young group but more type IIX (64.6+/-4.7% vs 51.8+/-11.1%). The MHC data are consistent with the age-related changes seen in other species.  相似文献   

Optical spectroscopy of individual single-walled carbon nanotubes of defined chiral structure     

Sfeir MY  Beetz T  Wang F  Huang L  Huang XM  Huang M  Hone J  O'Brien S  Misewich JA  Heinz TF  Wu L  Zhu Y  Brus LE 《Science (New York, N.Y.)》2006,312(5773):554-556

We simultaneously determined the physical structure and optical transition energies of individual single-walled carbon nanotubes by combining electron diffraction with Rayleigh scattering spectroscopy. These results test fundamental features of the excited electronic states of carbon nanotubes. We directly verified the systematic changes in transition energies of semiconducting nanotubes as a function of their chirality and observed predicted energy splittings of optical transitions in metallic nanotubes.  相似文献   

Homoploid hybrid speciation in an extreme habitat   总被引：1，自引：0，他引：1  

Gompert Z  Fordyce JA  Forister ML  Shapiro AM  Nice CC 《Science (New York, N.Y.)》2006,314(5807):1923-1925

According to theory, homoploid hybrid speciation, which is hybrid speciation without a change in chromosome number, is facilitated by adaptation to a novel or extreme habitat. Using molecular and ecological data, we found that the alpine-adapted butterflies in the genus Lycaeides are the product of hybrid speciation. The alpine populations possess a mosaic genome derived from both L. melissa and L. idas and are differentiated from and younger than their putative parental species. As predicted, adaptive traits may allow for persistence in the environmentally extreme alpine habitat and reproductively isolate these populations from their parental species.  相似文献   

Top-down vs. bottom-up effects in kelp forests     

Foster MS  Edwards MS  Reed DC  Schiel DR  Zimmerman RC 《Science (New York, N.Y.)》2006,313(5794):1737-9; author reply 1737-9

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Detecting awareness in the vegetative state     

Owen AM  Coleman MR  Boly M  Davis MH  Laureys S  Pickard JD 《Science (New York, N.Y.)》2006,313(5792):1402

We used functional magnetic resonance imaging to demonstrate preserved conscious awareness in a patient fulfilling the criteria for a diagnosis of vegetative state. When asked to imagine playing tennis or moving around her home, the patient activated predicted cortical areas in a manner indistinguishable from that of healthy volunteers.  相似文献   

Prion-induced amyloid heart disease with high blood infectivity in transgenic mice     

Trifilo MJ  Yajima T  Gu Y  Dalton N  Peterson KL  Race RE  Meade-White K  Portis JL  Masliah E  Knowlton KU  Chesebro B  Oldstone MB 《Science (New York, N.Y.)》2006,313(5783):94-97

We investigated extraneural manifestations in scrapie-infected transgenic mice expressing prion protein lacking the glycophosphatydylinositol membrane anchor. In the brain, blood, and heart, both abnormal protease-resistant prion protein (PrPres) and prion infectivity were readily detected by immunoblot and by inoculation into nontransgenic recipients. The titer of infectious scrapie in blood plasma exceeded 10(7) 50% infectious doses per milliliter. The hearts of these transgenic mice contained PrPres-positive amyloid deposits that led to myocardial stiffness and cardiac disease.  相似文献