Retrospective study of 942 small-sized dogs: Prevalence of left apical systolic heart murmur and left-sided heart failure, critical effects of breed and sex     

Pierre Serfass DVM  Valrie Chetboul DVM  PhD  Dipl ECVIM  Carolina Carlos Sampedrano DVM  MS  Audrey Nicolle DVM  Thierry Benalloul DVM  Herv Laforge DVM  Christophe Gau DVM  Carole Hbert DVM  Jean-Louis Pouchelon DVM  PhD  Renaud Tissier DVM  PhD 《Journal of Veterinary Cardiology》2006,8(1):11-18

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Mechanical behaviour of saturated wood under compression Part 2: Behaviour of wood at low rates of strain some effects of compression on wood structure     

M. Renaud  M. Rueff  A. C. Rocaboy 《Wood Science and Technology》1996,30(4):237-243

Summary The mechanical behaviour of three species of hardwoods, soaked in different liquids, had been investigated at high rates of strain using a Hopkinson pressure bar system. In order to determine the influence of the rate of strain, samples from the same species were subjected to compression-tests at low rates of strain. It was noticed that, at low rates of strain, the saturated samples were always less stiff than the dry ones, which is in agreement with the literature, but differs from the behaviour at high rates of strain. This difference is attributed to the behaviour of the liquid present in the large cavities of the material, which must depend on the rate of strain. It was also noticed that the samples could support higher stresses at high rates of strain. Although permanent sets were measured after the tests, the samples were not always visibly damaged, but some typical failures were detected by means of microscopy. The damaged zones presented similar aspects, whatever the rate of strain.  相似文献   

Analysis of chip formation mechanisms and modelling of slabber process     

Renaud Pfeiffer  Robert Collet  Louis Etienne Denaud  Guillaume Fromentin 《Wood Science and Technology》2015,49(1):41-58

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The conservation of the endangered Mediterranean common dolphin (Delphinus delphis): Current knowledge and research priorities     

Adriana Vella  Sinéad Murphy  Joan Giménez  Renaud de Stephanis  Barbara Mussi  Joseph G. Vella  Kamel Larbi Doukara  Daniela Silvia Pace 《水产资源保护:海洋与淡水生态系统》2021,31(Z1):110-136

1. Preservation of endangered species is now recognized as a relevant component of regional and global conservation actions achieved through the maintenance of the remaining populations in a favourable conservation status. The Mediterranean common dolphin (Delphinus delphis) is listed as an Endangered subpopulation in the International Union for Conservation of Nature Red List, with declining numbers in some of the areas where it has been studied for numerous years. Prey depletion, fisheries bycatch, pollution, health risks, and climate change are among the recognized threats that the species is facing in the region.
2. The existing national, regional, and international legislation pertinent to Mediterranean countries should aid greater science–policy–management integration and support innovative research and monitoring towards effective conservation. The challenges inherent in studying the pelagic D. delphis should not preclude the use of long-term, year-round, multiplatform surveys, side by side with the latest molecular tools, which aid our understanding of its populations' genetic diversity, resistance to diseases, and resilience in a semi-enclosed fast-changing sea.
3. Addressing the multiplicity of problems confronting the species requires collaborative effort at all levels to share and merge resources, data, and expertise more efficiently. In this review, we provide an overview of the current knowledge on the Mediterranean common dolphin, the main threats, and knowledge gaps that are priorities for addressing its conservation, while providing clear recommendations for effectively safeguarding the species and its habitat at both local and regional levels.

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Effect of cortisol on the metabolism of 17-hydroxyprogesterone by Arctic charr and rainbow trout embryos     

M.N. Khan  P.K. Reddy  R.L. Renaud  J.F. Leatherland 《Fish physiology and biochemistry》1997,16(3):197-209

The effect of cortisol on the in vitro metabolism of [³H]17-hydroxyprogesterone ([³H]17OHP) was studied during embryonic development of Arctic charr (Salvelinus alpinus) and rainbow trout (Oncorhynchus mykiss). In the absence of cortisol, rainbow trout embryos metabolized [³H]17OHP largely to androstenedione (A₄) and androstenetrione (11-KA) with a minor conversion to 17,20ß-dihydroxy-4-pregnen-3-one (17,20P). In the presence of cortisol, this biosynthesis was inhibited. On the other hand, cortisol had no apparent inhibitory effect on the nature of metabolism of [³H]17OHP by Arctic charr embryos. In these embryos [³H]17OHP was metabolized mainly to 17,20P with a minor conversion to A₄ and without the formation of 11-KA that was seen in rainbow trout.When incubated in the presence of [³H]cortisol both Arctic charr and rainbow trout embryos produced 11ß-hydroxyandrostenedione (11ß-OHA) as the major metabolite, with a minor conversion to an unknown steroid. The catabolism of the cortisol by salmonid embryos may reflect the ability of the embryo to inactivate or detoxify cortisol to protect itself from the adverse effects of this biologically potent steroid hormone The study indicates the existence of species-specific differences in the nature of metabolism of [³H]17OHP and the inhibitory effect of cortisol on this metabolism.  相似文献   

Characterization of suspended particulate matter in the Moselle River (Lorraine,France): evolution along the course of the river and in different hydrologic regimes     

Mathieu Le Meur  Emmanuelle Montargès-Pelletier  Allan Bauer  Renaud Gley  Sylvie Migot  Odile Barres  Claire Delus  Frédéric Villiéras 《Journal of Soils and Sediments》2016,16(5):1625-1642

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Agricultural studies of GM maize and the field experimental infrastructure of ECOGEN   总被引：4，自引：9，他引：4  

Mathias Neumann Andersen  Christophe Sausse  Bernard Lacroix  Sandra Caul  Antoine Messan 《Pedobiologia》2007,51(3):175-ECOGEN

Within the ECOGEN project, long-term field experiments with genetically modified maize, Zea mays L. were conducted to study agro-ecological effects on the soil fauna and agro-economic implications of the technology. Here, we describe the study-sites, experimental layout and results of agro-economic relevance. Experiments were conducted during 2002–2005 in Denmark (Foulum), northern France (Varois) and the Midi-Pyrenees region of southern France (Narbons). MON810 Bacillus thuringiensis (Bt)-varieties expressing the Cry1Ab protein, and a T25 glufosinate-ammonium (Basta) tolerant variety expressing the pat-gene encoding phosphinotrinacetyl-transferase were compared with near-isogenic non-Bt varieties, and conventional maize varieties. At Foulum, the maize was harvested for silage. There were no significant differences in yield between Bt-maize and a near-isogenic non-Bt variety, while a small difference in N-concentration of dry matter was detected in 1 year in a range of a measured quality parameters. Similar yield and quality were found in ploughed and reduced tillage treatments in all varieties. At Varois, the maize was harvested at ripeness and no significant differences in grain yield between Bt-maize and near-isogenic non-Bt varieties were found. These results were expected, as only Narbons harbours significant corn-borer populations. At Narbons, the number of Sesamia and Ostrinia corn-borer larvae were significantly lower in the Bt-maize than in a near-isogenic non-Bt variety and for Sesamia even less than in conventional varieties sprayed with pesticides to control corn-borer infestation. Here, Bt-maize produced a higher grain yield and grain size than a near-isogenic non-Bt variety or allowed a significant reduction in pesticide use. Concentrations of Cry1Ab in the Bt-varieties were sufficient to effectively control corn-borer larvae. In soil, Cry1Ab was close to the limit of detection and the protein did not accumulate in the soil year on year.  相似文献   

Combined effect of ascorbic acid and gamma irradiation on microbial and sensorial characteristics of beef patties during refrigerated storage     

Giroux M  Ouattara B  Yefsah R  Smoragiewicz W  Saucier L  Lacroix M 《Journal of agricultural and food chemistry》2001,49(2):919-925

The present study was undertaken to evaluate the effect of ascorbic acid concentrations (0.03 to 0.5%) and irradiation doses (0.5 to 4 kGy) on microbial growth, color coordinates (L, a, and b), and sensory characteristics (taste and odor) of beef patties during storage at 4 +/- 1 degrees C. Ascorbic acid was also compared to citric acid at a similar pH value in order to differentiate the effects of ascorbic acid from those of pH reduction. Results showed significant reduction (p< or = 0.05) of aerobic plate counts (APCs) and total coliforms, and a significant interaction (p< or = 0.05) between ascorbic acid and irradiation dose was observed. The irradiation treatment had detrimental effects on redness, yellowness, and hue angle values of meat. However, incorporation of ascorbic acid into the meat before irradiation resulted in significant (p< or = 0.05) stabilization of color parameters. The color improvement obtained with ascorbic acid was not related to the pH reduction. Also, no significant detrimental effect on taste or odor was found in irradiated samples containing ascorbic acid.  相似文献   

Development of biodegradable films from whey proteins by cross-linking and entrapment in cellulose   总被引：1，自引：0，他引：1  

Le Tien C  Letendre M  Ispas-Szabo P  Mateescu MA  Delmas-Patterson G  Yu HL  Lacroix M 《Journal of agricultural and food chemistry》2000,48(11):5566-5575

When cross-linked by heating or by gamma-irradiation and entrapped in cellulose, whey proteins can generate insoluble biofilms with good mechanical properties and high resistance to attack by proteolytic enzymes. Interchain cross-linking of proteins generated an increase in the puncture strength, and a decrease in water vapor permeability. Gelatin was added in film formulation as a stabilizer to improve the puncture strength and film appearance. The structure of the biofilms was also analyzed. SDS-PAGE revealed that heating and gamma-irradiation produce an increase of the molecular weight of the cross-linked protein. Size exclusion chromatography showed a molecular mass of 40 kDa for un-cross-linked whey proteins, whereas for the soluble fractions of the cross-linked proteins, molecular distributions were between 600 and 3800 kDa for the heated proteins and between 1000 and 2000 kDa for gamma-irradiated proteins. No major alteration of the structural conformation of the proteins was observed by FTIR for biofilms obtained after heat treatment, whereas gamma-irradiation induced some modifications in the protein structure. X-ray diffraction analysis suggests that cross-linking by gamma-irradiation seems to modify the conformation of proteins, which became more ordered and more stable.  相似文献   

Hepatic glucose sensing via the CREB coactivator CRTC2   总被引：1，自引：0，他引：1  

Dentin R  Hedrick S  Xie J  Yates J  Montminy M 《Science (New York, N.Y.)》2008,319(5868):1402-1405

Chronic hyperglycemia contributes to the development of diabetes-associated complications. Increases in the concentration of circulating glucose activate the hexosamine biosynthetic pathway (HBP) and promote the O-glycosylation of proteins by O-glycosyl transferase (OGT). We show that OGT triggered hepatic gluconeogenesis through the O-glycosylation of the transducer of regulated cyclic adenosine monophosphate response element-binding protein (CREB) 2 (TORC2 or CRTC2). CRTC2 was O-glycosylated at sites that normally sequester CRTC2 in the cytoplasm through a phosphorylation-dependent mechanism. Decreasing amounts of O-glycosylated CRTC2 by expression of the deglycosylating enzyme O-GlcNAcase blocked effects of glucose on gluconeogenesis, demonstrating the importance of the HBP in the development of glucose intolerance.  相似文献