Chemerin analog regulates energy metabolism in sheep     

Yutaka SUZUKI  Sang‐Houn SONG  Katsuyoshi SATO  Kyoung‐Ha SO  Astrid ARDIYANTI  Shun KITAYAMA  Yeon‐Hee HONG  Sung‐Dae LEE  Ki‐Choon CHOI  Akihiko HAGINO  Kazuo KATOH  Sang‐gun ROH 《Animal Science Journal》2012,83(3):263-267

Accumulating data suggest a relationship between chemerin and energy metabolism. Our group previously described gene cloning, expression analysis and the regulatory mechanism of chemerin and its own receptor in mice and cattle. The objective of the present study was to investigate the physiological effect of chemerin on endocrine changes and energy metabolism in sheep using a biologically stable chemerin analog. The chemerin analog was intravenously administrated (100 or 500 µg/head) to sheep, and plasma insulin and metabolites (glucose, nonesterified fatty acids (NEFA), triglyceride, total cholesterol and high‐density lipoprotein (HDL) cholesterol) were analyzed. The chemerin analog dramatically increased the insulin levels, and glucose levels were decreased. NEFA levels were slightly decreased at 20 min but then increased gradually from 60 to 180 min after analog administration. In addition, injection of the chemerin analog immediately increased triglyceride and total cholesterol but not HDL levels. These results suggested that chemerin analog regulated insulin secretion related to glucose metabolism and the release of triglycerides in sheep in vivo. This study provides new information about endocrine and metabolic changes in response to chemerin in sheep.  相似文献   

Prevalence of Toxoplasma gondii Infection in Rabbits of Korea by Serological Tests and Nested Polymerase Chain Reaction     

Hyun-Guk SHIN  Sang- Eun LEE  Sung-Hee HONG  Se-Mi KIM  Young-Ki CHOI  Hyung-Jin PARK  Kyoung-Won SEO  Kun-Ho SONG 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2013,75(12):1609-1613

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Absorption, translocation, and metabolism of fentrazamide in rice and early watergrass (Echinochloa oryzicola)     

SUNG J. LIM  YUKARI SUNOHARA  HIROSHI MATSUMOTO 《Weed Biology and Management》2008,8(3):215-218

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A case of chronic lymphocytic leukemia masked by Cushing’s disease in a dog     

Ju-Won CHOI  Su-Min KIM  Jung-Hyun KIM 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(7):1107

A 12-year-old, 3.5-kg, intact female dog was presented with polyuria, polydipsia, and a pendulous abdomen. Laboratory examinations showed elevated hepatobiliary enzyme levels and neutrophilic leukocytosis. The adrenocorticotropic hormone stimulation test confirmed hyperadrenocorticism (HAC). Trilostane therapy managed the clinical condition and cortisol concentration. However, lymphocytosis and nonregenerative anemia developed after HAC remission. Bone marrow aspiration analysis revealed a lymphoproliferative disorder with a clonal T-cell population. Accordingly, the patient was diagnosed with T-cell chronic lymphocytic leukemia (CLL) and concurrent HAC. Thereafter, chemotherapy was initiated, which improved the lymphocytosis. However, euthanasia was performed because of worsening quality of life at 45 weeks after the first presentation. These results suggested that CLL could be masked by excessive endogenous cortisol and discovered after HAC remission.  相似文献   

Inhibition of growth hormone secretagogue receptor antagonist, [D-Lys-3]-GHRP-6, in adipogenesis of ovine and rat adipocytes     

Sang-gun ROH  Yeon-hee HONG  Daisuke HISHIKAWA  Hiroaki TSUZUKI  Hisae MIYAHARA  Yukihiko NISHIMURA  Chizu GOTO  Yasuki SUZUKI  Ki-choon CHOI  Hong-gu LEE  Shinichi SASAKI 《Animal Science Journal》2005,76(4):381-386

Ghrelin and growth hormone secretagogues receptor (GHS‐R or ghrelin receptor) have been reported as being one of the factors of adipogenesis in adipocytes. To investigate the involvement of ghrelin and GHS‐R in adipocytes, the effect of the GHS‐R antagonist, [D‐Lys‐3]‐GHRP‐6 (His‐D‐Trp‐D‐Lys‐Trp‐D‐Phe‐Lys‐NH₂), on the process of adipogenesis in ovine and rat adipocytes was evaluated. [D‐Lys‐3]‐GHRP‐6 (10^?7 mol/L) significantly inhibited adipogenic differentiation of ovine and rat preadipocytes prepared from adipose tissues. The level of peroxisome proliferator activated receptor (PPAR)‐γ2 mRNA, an adipogenic marker, was decreased during the differentiation of adipocytes treated with [D‐Lys‐3]‐GHRP‐6 for 10 days. Ghrelin stimulated adipogenesis, also causing an increment of glycerol‐3‐phosphate dehydrogenase and upregulation of PPAR‐γ2. Furthermore, the antilipolytic effect of ghrelin was attenuated by treatment with [D‐Lys‐3]‐GHRP‐6 in both types of isolated adipocytes. Overall, the results of the present study highlight that GHS‐R in adipogenesis can be blocked by treatment with [D‐Lys‐3]‐GHRP‐6.  相似文献   

Effects of salt stress on ion accumulation and antioxidative enzyme activities of Oryza sativa L. and Echinochloa oryzicola Vasing     

HOAI THI THU NGUYEN  IE SUNG SHIM  KATSUICHIRO KOBAYASHI  KENJI USUI 《Weed Biology and Management》2005,5(1):1-7

The effects of salt stress on physiological factors, such as inorganic ion absorption and antioxidative enzyme activities, of rice ( Oryza sativa L. cv. Anapurna) and Echinochloa oryzicola Vasing were investigated. Although having similar morphology, rice and E. oryzicola possessed considerably different salt-tolerance mechanisms. Echinochloa oryzicola was more salt-tolerant than rice. When exposed to salt stress (100 mmol L⁻¹ sodium chloride, NaCl; six days), E. oryzicola had the ability to limit the accumulation of sodium ions (Na⁺), maintained high potassium ion (K⁺) content and had a constantly higher K⁺/Na⁺ ratio than rice. Rice was not effective in limiting Na⁺ absorption but had a higher antioxidative capacity than E. oryzicola . The constitutive activities of superoxide dismutase (SOD) and catalase of rice were three and five times higher than that of E. oryzicola, respectively. Induced activities of SOD, ascorbate peroxidase and glutathione reductase were also higher in rice than in E. oryzicola . The high antioxidative capacity was one of the tolerance mechanisms used by rice to cope with salt stress. Therefore, the salt tolerant-mechanisms are different between the two plants.  相似文献   

Pretilachlor tolerance in some perennial weeds is attributable to their higher cytochrome P‐450 activities     

IE‐SUNG SHIM  MIN‐SOO YUN  KATSUICHIRO KOBAYASHI  KENJI USUI 《Weed Biology and Management》2002,2(4):205-208

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Evidence of density-dependent effects on population variation of Japanese sardine (Sardinops melanosticta) off Korea     

JIN YEONG KIM  SUAM KIM  YOUNG MIN CHOI  JAE BONG LEE 《Fisheries Oceanography》2006,15(4):345-349

Interannual variation of some biological parameters for the Japanese sardine, Sardinops melanosticta, population in Korean waters was investigated using scientific surveys and fisheries information since the late 1970s. The abundance and geographical coverage of sardine eggs were high (peak in 1986) and broad when spawning biomasses were high in the mid 1980s, and vice versa in the late 1970s and the early 1990s. Also, feeding and spawning areas based on fisheries information exhibited the same pattern of expansion/contraction as seen in ichthyoplankton surveys. Annual Gonadal Somatic Index (GSI) in spawning season (February to April) and the size at age 1 of sardine were reduced during the high abundance period. It is suggested that density‐dependent effects on the reproduction and growth of the sardine population in Korean waters existed.  相似文献   

Conservation status of Chinese species: (1) Overview     

Yan XIE  Wang SUNG 《Integrative zoology》2007,2(1):26-35

The first comprehensive evaluation of more than 10 000 species in China based on the IUCN Red List Criteria and Regional Guidelines is complete. More than 100 experts have been involved in this evaluation, which covers a wide range of species, including invertebrates, vertebrates, gymnosperms and angiosperms. The present paper summarizes the major conclusions of the project. The number of threatened species in China was found to be much high than previously expected. In the past, the estimated percentages of species in each phylum that were endangered was 2‐30%. In this comprehensive evaluation, the percentages of threatened species were found to be 7.4‐100%. Compared with the status of threatened species worldwide (IUCN Red List 2006), groups such as fish, mammals and gymnosperms face much higher levels of threat in China then they do globally, and other groups, such as crustaceans, reptiles and birds, face lower levels of threat. Given the dire conclusions of this study, we recommend that more research be done on the threats faced by those groups of organisms that are most threatened.  相似文献   

IMAGING DIAGNOSIS—PEROSOMUS ELUMBIS IN A KOREAN CALF     

YOUNGWON LEE  HOJUNG CHOI  DONGWOO CHANG  KIDONG EOM  JUNGHEE YOON  MINCHEOL CHOI  KICHANG LEE  SEONGCHAN YEON  HYOJONG LEE  CHUNGKIL WON  HEECHUN LEE 《Veterinary radiology & ultrasound》2007,48(1):30-31

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