Efficacy of a continuous, multiagent chemotherapeutic protocol versus a short-term single-agent protocol in dogs with lymphoma   总被引：1，自引：0，他引：1  

Simon D  Moreno SN  Hirschberger J  Moritz A  Kohn B  Neumann S  Jurina K  Scharvogel S  Schwedes C  Reinacher M  Beyerbach M  Nolte I 《Journal of the American Veterinary Medical Association》2008,232(6):879-885

OBJECTIVE: To compare response rates and remission and survival times in dogs with lymphoma treated with a continuous, multiagent, doxorubicin-based chemotherapeutic protocol or with a short-term single-agent protocol incorporating doxorubicin. DESIGN: Nonrandomized controlled clinical trial. ANIMALS: 114 dogs with lymphoma. PROCEDURES: Dogs were treated with a chemotherapeutic protocol consisting of L-asparaginase, vincristine, cyclophosphamide, doxorubicin, methotrexate, and prednisolone (n=87) or doxorubicin alone (27). RESULTS: 63 of 86 (73%) dogs treated with the multiagent protocol (data on response was unavailable for 1 dog) and 14 of 27 (52%) dogs treated with the single-agent protocol had a complete remission. Dogs with lymphoma classified as substage相似文献   

Mycoplasma mastitis in dairy cattle     

Tolboom RK  Snoep JJ  Sampimon OC  Sol J  Lam TJ 《Tijdschrift voor diergeneeskunde》2008,133(3):96-101

The most important characteristics of Mycoplasma mastitis on dairy farms are described, based on two case studies. Clinical symptoms, diagnostics, epidemiology, and a plan of action are presented. In the herds investigated, Mycoplasma mastitis was characterized by multiple affected quarters unresponsive to treatment with antibiotic and/or anti-inflammatory agents. Most striking were a sandy sediment, brown colouring, and rice-like structure of the milk of affected animals. Clinical symptoms differed in the two affected herds. Diagnosis was based on bacteriological investigation of samples of milk and synovial fluid taken from infected cows. Affected animals were culled immediately, and the herds were monitored by repeated testing of bulk milk samples. It was concluded that a consequence of the increasing size of cattle herds in the Netherlands is that subclinical/clinical Mycoplasma mastitis may be diagnosed more frequently than in the past. In the case of Mycoplasma mastitis, farmers and veterinary practitioners are advised to draw up a plan of action together, incorporating aspects such as diagnostics at cow level, direct culling of affected animals, hygiene during milking, including post-milking teat disinfection, and routine monitoring of bulk milk. Unpasteurized milk should not be given to calves.  相似文献   

New records of Rhipicephalus linnaei infected by Rickettsia massiliae from Central Mexico     

José Francisco Nieto-Cabrales  Beatriz Salceda-Sánchez  Héctor M. Zazueta-Islas  Marlene Solís-Cortés  Magaly Guadalupe Landa-Flores  Juan Carlos del Mazo-López  Laura Valtierra-Alzaga  Juan J. Soto-Gutiérrez  Heron Huerta-Jimenez  Ingeborg Becker  Jorge J. Rodríguez-Rojas  Sokani Sánchez-Montes 《Zoonoses and public health》2024,71(2):217-224

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Alteration in the susceptibility ofvicia faba toBotrytis fabae by various pretreatments of the leaves     

H. H. Sol 《European journal of plant pathology / European Foundation for Plant Pathology》1966,72(3-6):196-202

Infection of broad bean leaves byBotrytis fabae was influenced by various pretreatments of the leaves. The number of lesions developing on test leaflets increased after pretreatment of the leaflet for 24 hours with a sucrose, a potassium chloride or a lanthanum chloride solution; pretreatment of leaflets by keeping them in darkness had a similar effect. At least the first phase of the infection process, viz. germination of the conidia on the leaf, was stimulated by these pretreatments. This stimulation may have been caused by increased amounts of leached nutrients present on the pretreated leaflets in comparison with those on untreated ones.  相似文献   

The transmission of rattle virus byTrichodorus pachydermus     

H. H. Sol  J. W. Seinhorst 《European journal of plant pathology / European Foundation for Plant Pathology》1961,67(4):307-309

Samenvatting De nematode-soortTrichodorus pachydermus Seinhorst kan ratelvirus overbrengen naar gezonde White Burley tabaksplanten. Eén aaltje, geïsoleerd uit met ratelvirus besmette grond, is zelfs in staat een tabaksplant met het virus te infecteren.Evenals ratelvirus komt deze nematode-soort vooral voor in lichtere grondsoorten. In kleigrond worden beide zelden aangetroffen. Het is mogelijk, dat de verspreiding van het virus beperkt is tot gebieden waarT. pachydermus voorkomt. Dit moet nog nader worden onderzocht.  相似文献   

Transmission of rattle virus andAtropa belladonna mosaic virus by nematodes     

H. H. Sol  J. C. van Heuven  J. W. Seinhorst 《European journal of plant pathology / European Foundation for Plant Pathology》1960,66(3):228-231

Samenvatting Met ratelvirus en mozaïekvirus vanAtropa belladonna, twee op elkaar gelijkende grondvirussen, werden proeven gedaan over een mogelijke overbrenging door aaltjes.Nematoden uit met virus besmette grond werden toegevoegd aan natuurlijke, onbesmette grond, aan tot 60°C of 120°C verhitte en aan gewreven grond. Door wrijven van de grond worden de meeste aaltjes en andere organismen van dezelfde afmetingen gedood. In de aldus behandelde en geïnoculeerde grond werden tabaksplanten geteeld. Bij de proeven met mozaïekvirus vanAtropa belladonna werden tien dagen na het planten de wortels uitgeperst en het sap met carborundum uitgewreven op bladeren van gezonde tabaksplanten. Bij de proeven met ratelvirus werd dit alleen gedaan met planten, die dertig dagen na het planten geen symptomen vertoonden.Virusinfectie trad niet op in de proeven, waar aaltjes niet de overbrengers konden zijn. Aaltjes uit besmette grond brachten in zeer veel gevallen virus naar onbesmette grond over (tabellen 1 en 2). Hoplolaimus uniformis enHemicycliophora sp. brengen het ratelvirus waarschijnlijk niet over. De proeven worden voortgezet met andere soorten aaltjes.  相似文献   

Allergic contact dermatitis of bovine teat skin caused by milking machine cluster rubber     

Holzhauer M  Sampimon OC  Sol J  van Walderveen A  van Ginkel CJ 《The Veterinary record》2004,154(7):208-209

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Agroforestry systems in the highlands of the Tehuacán Valley,Mexico: indigenous cultures and biodiversity conservation     

Mariana Vallejo  Alejandro Casas  José Blancas  Ana I. Moreno-Calles  Leonor Solís  Selene Rangel-Landa  Patricia Dávila  Oswaldo Téllez 《Agroforestry Systems》2014,88(1):125-140

In this study we analysed: (1) the biodiversity conservation capacity of Agroforestry Systems (AFS) in temperate highlands of the Tehuacán–Cuicatlán Valley, Central Mexico, (2) human cultural motives and actions for conserving such diversity and (3) problems endangering that capacity. We evaluated the richness and diversity of perennial plant species maintained in AFS through vegetation sampling of 14 agricultural plots and compared their composition with that of natural forests (14 plots of 500 m² each). We examined the situations among communities of Náhuatl, Ixcatec and Cuicatec people, documenting through interviews the management practices of plant species and the whole system, reasons why people maintain vegetation cover within AFS, and factors influencing changes in decisions favouring agriculture intensification. In the AFS studied we recorded a total of 79 species of trees and shrubs, 86 % of them being native species and representing 43 % of all species of trees and shrubs recorded in the sampling of the natural forests the AFS derive from. People leave standing on average a total of 40 individual trees and shrubs per agricultural plot. Reasons for leave plant species standing were more frequently associated with their use as fruit trees, firewood, shade, beauty, respect to nature and other environmental benefits. Water availability for irrigation, land tenure, and dependence on agriculture and forest for peasant's subsistence were main decision factors influencing AFS variation in their composition. AFS in temperate zones are important reservoirs of biodiversity and biocultural heritage and should be keystones for conservation policies in the Tehuacán–Cuicatlán Valley.  相似文献   

Relationship between pregnancy rate and serum progesterone concentration in cases of porcine embryo transfer     

JoonHo Moon  Ji-Yei Choi  Jung-Taek Kang  Sol Ji Park  Su Jin Kim  Goo Jang  Byeong Chun Lee 《Journal of veterinary science (Suw?n-si, Korea)》2014,15(1):167-171

The level of P4 at the time of embryo transfer (ET) is important. P4 concentrations and numbers of corpora lutea for 126 recipients were evaluated. Nuclear transfer embryos were transferred into 126 surrogates. 11 maintained their pregnancy until full-term delivery, 17 miscarried, and implantation failed in 98 animals. P4 levels in the full-term group were significantly different from those of the pigs that aborted or in which implantation failed (p < 0.05). However, the numbers of corpora lutea were not significantly different. These findings indicate that the concentration of progesterone can be an important factor for successful ET in pigs.  相似文献   

(Amino)(aryl)carbenes: stable singlet carbenes featuring a spectator substituent     

Solé S  Gornitzka H  Schoeller WW  Bourissou D  Bertrand G 《Science (New York, N.Y.)》2001,292(5523):1901-1903

Several (amino)(aryl)carbenes have been shown to be stable at room temperature in solution and in the solid state. Electroneutrality of the carbene center is ensured by the amino group, which has both pi-donor and final sigma-acceptor electronic character. The aryl group remains a spectator substituent, as shown by single-crystal x-ray analysis and by its chemical behavior. Because only one electron-active substituent is needed, numerous stable carbenes will become accessible, which will open the way for new synthetic developments and applications in various fields.  相似文献