Feline toxicological emergencies: when to suspect and what to do     

Grave TW  Boag AK 《Journal of Feline Medicine and Surgery》2010,12(11):849-860

PRACTICAL RELEVANCE: Confirmed or suspected intoxications with a wide variety of agents represent a small but important group of feline emergency cases. Generally it is thought that toxicities are less common in cats compared with dogs, with a higher proportion relating to dermal as opposed to oral exposure. CLINICAL CHALLENGES: Once toxicity is suspected or diagnosed, it must be recognised that treatment regimes may need modification compared with those established for dogs. Different drugs or different dosages may be warranted and the choice of available drugs may be reduced. EVIDENCE BASE: This review draws on published studies, case reports and clinical experience to summarise key features of the general management of the intoxicated feline patient before describing some of the more serious and common intoxications in more detail. AUDIENCE: The focus throughout the review is on the peculiarities of feline metabolism and how they may impact on presentation and treatment. The aim is to assist companion animal and feline practitioners, who are in the frontline when it comes to managing these emergency cases.  相似文献   

Signs of left heart volume overload in severely anaemic cats     

Helen E. Wilson BVSc  Shailen Jasani MA  VetMB  Tobias B. Wagner Dr Med Vet  Livia Benigni DVM Dip ECVDI CertVDI  Joanna R. Milne BVMS  Alison L. Stokes BVetMed  Virginia Luis-Fuentes MA  VetMB  PhD  CertVR  DVC  Dip ACVIM  Dip ECVIM-CA 《Journal of Feline Medicine and Surgery》2010,12(12):904-909

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Land-cover change and human population trends in the greater Serengeti ecosystem from 1984–2003     

Anna Bond Estes  Tobias Kuemmerle  Hadas Kushnir  Volker Christian Radeloff  Herman Henry Shugart 《Biological conservation》2012,147(1):255-263

The growth of human populations around protected areas accelerates land conversion and isolation, negatively impacting biodiversity and ecosystem function, and can be exacerbated by immigration. It is often assumed that immigration around protected areas is driven by attraction in the form of economic benefits, but in many cases, people may be pushed from their areas of origin toward protected areas. Mitigating the effects of immigration around protected areas necessitates understanding the actual mechanisms causing it, which can be aided by analysis of patterns of land-cover change. Our goal was to identify the reasons for human population growth and land-cover change around the protected areas in the greater Serengeti ecosystem (henceforth “the park”), and to relate agricultural conversion from 1984–2003 to trends in human demography. We found that conversion of natural habitats to agriculture was greatest closer to the park (up to 2.3% per year), coinciding with the highest rates of human population growth (3.5% per year). Agricultural conversion and population growth were greatest where there was less existing agriculture, and population density was lowest. Lack of unfarmed land farther from the park, coupled with greater poverty near the park, suggest that movement away from areas with high population densities and land scarcity was likely driving immigration near the park, where arable land was available. Our results are essential for conservation planning for one of Africa’s hallmark ecosystems, and should encourage further examination of population growth and land-cover trends near protected areas throughout the developing world.  相似文献   

Occurrence of tympanic bone spicules and bone crests in domestic cats     

Tobias Beck  Andreas Brühschwein  Andrea Meyer-Lindenberg 《Anatomia, histologia, embryologia》2020,49(2):216-221

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Effect of calcareous and siliceous amendments on N2O emissions of a grassland soil     

Teodora Todorcic Vekic  Shahid Nadeem  Lars Molstad  Vegard Martinsen  Elisabeth Gautefall Hiis  Lars Bakken  Tobias Rütting  Leif Klemedtsson  Peter Dörsch 《Soil Use and Management》2023,39(3):1082-1095

Liming of acidic agricultural soils has been proposed as a strategy to mitigate nitrous oxide (N₂O) emissions, as increased soil pH reduces the N₂O/N₂ product ratio of denitrification. The capacity of different calcareous (calcite and dolomite) and siliceous minerals to increase soil pH and reduce N₂O emissions was assessed in a 2-year grassland field experiment. An associated pot experiment was conducted using homogenized field soils for controlling spatial soil variability. Nitrous oxide emissions were highly episodic with emission peaks in response to freezing–thawing and application of NPK fertilizer. Liming with dolomite caused a pH increase from 5.1 to 6.2 and reduced N₂O emissions by 30% and 60% after application of NPK fertilizer and freezing–thawing events, respectively. Over the course of the 2-year field trial, N₂O emissions were significantly lower in dolomite-limed than non-limed soil (p < .05), although this effect was variable over time. Unexpectedly, no significant reduction of N₂O emission was found in the calcite treatment, despite the largest pH increase in all tested minerals. We tentatively attribute this to increased N₂O production by overall increase in nitrogen turnover rates (both nitrification and denitrification) following rapid pH increase in the first year after liming. Siliceous materials showed little pH effect and had no significant effect on N₂O emissions probably because of their lower buffering capacity and lower cation content. In the pot experiment using soils taken from the field plots 3 years after liming and exposing them to natural freezing–thawing, both calcite (p < .01) and dolomite (p < .05) significantly reduced cumulative N₂O emission by 50% and 30%, respectively, relative to the non-limed control. These results demonstrate that the overall effect of liming is to reduce N₂O emission, although high lime doses may lead to a transiently enhanced emission.  相似文献   

Elastic moduli of living epithelial pancreatic cancer cells and their skeletonized keratin intermediate filament network     

Walter N  Busch T  Seufferlein T  Spatz JP 《Biointerphases》2011,6(2):79-85

In simple epithelia, such as living epithelial pancreatic cancer cells (Panc-1), unusual amounts of keratin filaments can be found, which makes these cells an ideal model system to study the role of keratin for cell mechanical properties. In this work, the elastic moduli of Panc-1 cells and their extracted in-situ subcellular keratin intermediate filament network are determined and compared with each other. For this, the living adherent cells and their extracted keratin network were probed with local quasistatic indentation testing during large deformations using the Atomic Force Microscope (AFM). We determined the elastic modulus of the skeletonized but structurally intact keratin network to be in the order of 10 Pa, while the living cell elastic modulus ranged from 100 to 500 Pa. By removing microfilaments, microtubules, membranes and soluble cytoplasmic components during keratin network extraction, we excluded effects caused by crosslinking with other filamentous fibers and from the viscosity of the cytoplasm. Thus, the determined elastic modulus equals the actual elastic modulus inherent to such a keratin filamentous network. In our assessment of the effective mechanical contribution of the architecturally intact, skeletonized keratin network to living cell mechanics, we come to the conclusion that it plays only a very limited role. Evidently, the quantitative dominance of keratin in these cells does not reflect a strong influence on determining the cell's elastic modulus. Instead, keratin like other filamentous structures in the cell's scaffolding, e.g., F-actin and microtubuli, is one part of a greater whole.  相似文献   

Context matters: the landscape matrix determines the population genetic structure of temperate forest herbs across Europe     

Naaf  Tobias  Feigs  Jannis Till  Huang  Siyu  Brunet  Jörg  Cousins  Sara A. O.  Decocq  Guillaume  De Frenne  Pieter  Diekmann  Martin  Govaert  Sanne  Hedwall  Per-Ola  Lenoir  Jonathan  Liira  Jaan  Meeussen  Camille  Plue  Jan  Vangansbeke  Pieter  Vanneste  Thomas  Verheyen  Kris  Holzhauer  Stephanie I. J.  Kramp  Katja 《Landscape Ecology》2022,37(5):1365-1384

Landscape Ecology - Plant populations in agricultural landscapes are mostly fragmented and their functional connectivity often depends on seed and pollen dispersal by animals. However, little is...  相似文献   

Comparative morphology of the snake spectacle using light and transmission electron microscopy          下载免费PDF全文

Mari‐Ann O. Da Silva  Mads F. Bertelsen  Tobias Wang  Jan U. Prause  Thøger Svahn  Steffen Heegaard 《Veterinary ophthalmology》2016,19(4):285-290

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Tachycardia in response to remote capsaicin injection as a model for nociception in the ball python (Python regius)          下载免费PDF全文

Catherine J A Williams  Lauren E James  Mads F Bertelsen  Tobias Wang 《Veterinary anaesthesia and analgesia》2016,43(4):429-434

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Analyzing dynamics and values of cultural landscapes     

Matthias Bürgi  Peter H. Verburg  Tobias Kuemmerle  Tobias Plieninger 《Landscape Ecology》2017,32(11):2077-2081

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