Feline lymphosarcoma treatment trial     

MJ STUDDERT 《Australian veterinary journal》1994,71(10):351-351

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Experimental transmission of a herpesvirus in Greek tortoises (Testudo graeca)     

Origgi FC  Romero CH  Bloom DC  Klein PA  Gaskin JM  Tucker SJ  Jacobson ER 《Veterinary pathology》2004,41(1):50-61

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Dialkyl 3,3'-thiodipropionate and dialkyl 2,2'-thiodiacetate antioxidants by lipase-catalyzed esterification and transesterification     

Weber N  Klein E  Vosmann K 《Journal of agricultural and food chemistry》2006,54(8):2957-2963

Medium- and long-chain dialkyl 3,3'-thiodipropionate antioxidants such as dioctyl 3,3'-thiodipropionate, didodecyl 3,3'-thiodipropionate, dihexadecyl 3,3'-thiodipropionate, and di-(cis-9-octadecenyl) 3,3'-thiodipropionate were prepared in high yield by lipase-catalyzed esterification and transesterification of 3,3'-thiodipropionic acid and its dimethyl ester, respectively, with the corresponding medium- or long-chain 1-alkanols, i.e., 1-octanol, 1-dodecanol, 1-hexadecanol, and cis-9-octadecen-1-ol, in vacuo (80 kPa) at moderate temperatures (60-80 degrees C) without solvents. Immobilized lipase B from Candida antarctica (Novozym 435) was the most active biocatalyst for the preparation of medium- and long-chain dialkyl 3,3'-thiodipropionates showing enzyme activities up to 1489 units/g, whereas the immobilized lipases from Rhizomucor miehei (Lipozyme RM IM) and Thermomyces lanuginosus (Lipozyme TL IM) were by far less active ( approximately 10 enzyme units/g). Maximum conversions to dialkyl 3,3'-thiodipropionates were as high as 92-98% after 4 h of reaction time. Similarly, dihexadecyl 2,2'-thiodiacetate was prepared in high yield using 2,2'-thiodiacetic acid or diethyl 2,2'-thiodiacetate and 1-hexadecanol as the starting materials and Novozym 435 as the biocatalyst.  相似文献   

Global control of dimorphism and virulence in fungi     

Nemecek JC  Wüthrich M  Klein BS 《Science (New York, N.Y.)》2006,312(5773):583-588

Microbial pathogens that normally inhabit our environment can adapt to thrive inside mammalian hosts. There are six dimorphic fungi that cause disease worldwide, which switch from nonpathogenic molds in soil to pathogenic yeast after spores are inhaled and exposed to elevated temperature. Mechanisms that regulate this switch remain obscure. We show that a hybrid histidine kinase senses host signals and triggers the transition from mold to yeast. The kinase also regulates cell-wall integrity, sporulation, and expression of virulence genes in vivo. This global regulator shapes how dimorphic fungal pathogens adapt to the mammalian host, which has broad implications for treating and preventing systemic fungal disease.  相似文献   

Residual feed intake of purebred Angus steers: effects on meat quality and palatability   总被引：1，自引：0，他引：1  

Baker SD  Szasz JI  Klein TA  Kuber PS  Hunt CW  Glaze JB  Falk D  Richard R  Miller JC  Battaglia RA  Hill RA 《Journal of animal science》2006,84(4):938-945

Relationships between residual feed intake (RFI) and other performance variables were determined using 54 purebred Angus steers. Individual feed intake and BW gain were recorded during a 70-d post-weaning period to calculate RFI. After the 70-d post-weaning test, steers were fed a finishing ration to a similar fat thickness (FT), transported to a commercial facility, and slaughtered. A subsample of carcasses (n = 32) was selected to examine the relationships among RFI, meat quality, and palatability. Steers were categorized into high (> 0.5 SD above the mean; n = 16), medium (mid; +/- 0.5 SD from the mean; n = 21), and low (< 0.5 SD below the mean; n = 17) RFI groups. No differences were detected in ADG, initial BW, and d 71 BW among the high, mid, and low RFI steers. Steers from the high RFI group had a greater DMI (P = 0.004) and feed conversion ratio (FCR; DMI:ADG; P = 0.002) compared with the low RFI steers. Residual feed intake was positively correlated with DMI (r = 0.54; P = 0.003) and FCR (r = 0.42; P = 0.002), but not with initial BW, d 71 BW, d 71 ultrasound FT, initial ultrasound LM area, d 71 ultrasound LM area, or ADG. The FCR was positively correlated with initial BW (r = 0.46; P = 0.0005), d 71 BW (r = 0.34; P = 0.01), and DMI (r = 0.40; P = 0.003) and was negatively correlated with ADG (r = -0.65; P = 0.001). There were no differences among RFI groups for HCW, LM area, FT, KPH, USDA yield grade, marbling score, or quality grade. Reflectance color b* scores of steaks from high RFI steers were greater (P = 0.02) than those from low RFI steers. There was no difference between high and low RFI groups for LM calpastatin activity. Warner-Bratzler shear force and sensory panel tenderness and flavor scores of steaks were similar across RFI groups. Steaks from high RFI steers had lower (P = 0.04) off-flavor scores than those from low RFI steers. Cook loss percentages were greater (P = 0.005) for steaks from low RFI steers than for those from mid RFI steers. These data support current views that RFI is independent of ADG, but is correlated with DMI and FCR. Importantly, the data also support the hypothesis that there is no relationship between RFI and beef quality in purebred Angus steers.  相似文献   

Organization of risk analysis in the EU and the new EU food regulation     

Pina MC  Ferrer C  Rodrigo M  Klein G  Martínez A 《DTW. Deutsche tier?rztliche Wochenschrift》2006,113(11):407-412

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Second-harmonic generation from magnetic metamaterials     

Klein MW  Enkrich C  Wegener M  Linden S 《Science (New York, N.Y.)》2006,313(5786):502-504

We observe second-harmonic generation from metamaterials composed of split-ring resonators excited at 1.5-micrometer wavelength. Much larger signals are detected when magnetic-dipole resonances are excited, as compared with purely electric-dipole resonances. The experiments are consistent with calculations based on the magnetic component of the Lorentz force exerted on metal electrons-an intrinsic second-harmonic generation mechanism that plays no role in natural materials. This unusual mechanism becomes relevant in our work as a result of the enhancement and the orientation of the local magnetic fields associated with the magnetic-dipole resonances of the split-ring resonators.  相似文献   

Land degradation and population relocation in Northern China     

Chong Dong  Xiumei Liu  K.K. Klein 《Asia Pacific viewpoint》2012,53(2):163-177

Overgrazing in the grasslands of Inner Mongolia following market reform in China has led to severe soil degradation and desertification. In an effort to revive the ecological environment in northern pastoral areas, the government of China recently adopted an intervention policy to relocate families from areas where excess grazing pressure was seriously compromising land and the environment. A survey was conducted in three villages to determine how well the relocated families have adapted to their new living conditions and the factors that affect their willingness to stay in the new villages. Regression analysis revealed that the most important factors were age of the head of the household, length of time the family has resided in the new village, proportion of total income that is made up of government payments and level of fixed, durable and current assets.  相似文献   

Sustainable activities is taking advantage of chances     

Haneveld JK 《Tijdschrift voor diergeneeskunde》2012,137(6):396-397

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Faculty: 'Applying alternative medicine gives false hope'     

Haneveld JK 《Tijdschrift voor diergeneeskunde》2012,137(6):400-401

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