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81.
Effects of interactive scale-dependent variables on beetle diversity patterns in a semi-arid agricultural landscape 总被引:3,自引:0,他引:3
Understanding species-diversity patterns in heterogeneous landscapes invites comprehensive research on how scale-dependent
processes interact across scales. We used two common beetle families (Tenebrionidae, detrivores; Carabidae, predators) to
conduct such a study in the heterogeneous semi-arid landscape of the Southern Judean Lowland (SJL) of Israel, currently undergoing
intensive fragmentation. Beetles were censused in 25 different-sized patches (500–40,000 m2). We used Fisher’s α and non-parametric extrapolators to estimate species diversity from 11,125 individuals belonging to
56 species. Patch characteristics (plant species diversity and cover, soil cover and degree of stoniness) were measured by
field transects. Spatial variables (patch size, shape, physiognomy and connectivity) and landscape characteristics were analyzed
by GIS and remote-sensing applications. Both patch-scale and landscape-scale variables affected beetle species diversity.
Path-analysis models showed that landscape-scale variables had the strongest effect on carabid diversity in all patches. The
tenebrionids responded differently: both patch-scale and landscape-scale variables affected species diversity in small patches,
while mainly patch-scale variables affected species diversity in large patches. Most of the paths affected species diversity
both directly and indirectly, combining the effects of both patch-scale and landscape-scale variables. These results match
the biology of the two beetle families: Tenebrionidae, the less mobile and more site-attached family, responded to the environment
in a fine-grained manner, while the highly dispersed Carabidae responded to the environment in a coarse-grained manner. We
suggest that understanding abiotic and biotic variable interactions across scales has important consequences for our knowledge
of community structure and species diversity patterns at large spatial scales. 相似文献
82.
Simmons G Glynn SA Komaroff AL Mikovits JA Tobler LH Hackett J Tang N Switzer WM Heneine W Hewlett IK Zhao J Lo SC Alter HJ Linnen JM Gao K Coffin JM Kearney MF Ruscetti FW Pfost MA Bethel J Kleinman S Holmberg JA Busch MP;Blood XMRV Scientific Research Working Group 《Science (New York, N.Y.)》2011,334(6057):814-817
Murine leukemia viruses (MLVs), including xenotropic-MLV-related virus (XMRV), have been controversially linked to chronic fatigue syndrome (CFS). To explore this issue in greater depth, we compiled coded replicate samples of blood from 15 subjects previously reported to be XMRV/MLV-positive (14 with CFS) and from 15 healthy donors previously determined to be negative for the viruses. These samples were distributed in a blinded fashion to nine laboratories, which performed assays designed to detect XMRV/MLV nucleic acid, virus replication, and antibody. Only two laboratories reported evidence of XMRV/MLVs; however, replicate sample results showed disagreement, and reactivity was similar among CFS subjects and negative controls. These results indicate that current assays do not reproducibly detect XMRV/MLV in blood samples and that blood donor screening is not warranted. 相似文献
83.
Afek Y Alon N Barad O Hornstein E Barkai N Bar-Joseph Z 《Science (New York, N.Y.)》2011,331(6014):183-185
Computational and biological systems are often distributed so that processors (cells) jointly solve a task, without any of them receiving all inputs or observing all outputs. Maximal independent set (MIS) selection is a fundamental distributed computing procedure that seeks to elect a set of local leaders in a network. A variant of this problem is solved during the development of the fly's nervous system, when sensory organ precursor (SOP) cells are chosen. By studying SOP selection, we derived a fast algorithm for MIS selection that combines two attractive features. First, processors do not need to know their degree; second, it has an optimal message complexity while only using one-bit messages. Our findings suggest that simple and efficient algorithms can be developed on the basis of biologically derived insights. 相似文献
84.
A correlation between platelet monoamine oxidase activity and plasma prolactin concentrations in man 总被引:1,自引:0,他引:1
J E Kleinman S Potkin A Rogol M S Buchsbaum D L Murphy J C Gillin H A Nasrallah R J Wyatt 《Science (New York, N.Y.)》1979,206(4417):479-481
Increases in plasma prolactin concentrations produced by alpha-methyl-p-tyrosine, a catecholamine synthesis inhibitor, varied inversely with baseline platelet monoamine oxidase activity in 12 patients with chronic schizophrenia. In normal volunteers with low monoamine oxidase activity and in unmedicated patients with chronic schizophrenia, plasma prolactin concentrations varied directly with platelet monoamine oxidase activity. No such relationship was found in normal subjects with high platelet monoamine oxidase activity. These data suggest that platelet monoamine oxidase activity reflects monoaminergic activity in the tubero-infundibular system, which in turn affects plasma prolactin concentrations. This relationship may be important in patients with low platelet monoamine oxidase activity, such as some chronic schizophrenics. 相似文献
85.
Lavy Ziv Shem-Tov Glickman & Dey 《Journal of veterinary pharmacology and therapeutics》1999,22(4):261-265
A buffered aqueous solution of clindamycin Hcl (200 mg/mL) was injected intravenously (i.v.) intramuscularly (i.m.) and subcutaneously (s.c.) in a non-randomized, partial cross-over trial involving six male and six female dogs. Blood samples were collected at conventional, predetermined time periods and serum drug concentrations were determined by microbiological assay. Dogs were observed clinically for signs of pain, and activity of serum creatine phosphokinase (CPK) was monitored after i.m. dosing. The i.v. data from five of the dogs best fitted a two-compartment open-system pharmacokinetic model whereas a non-compartment model was most suitable for analysis of the data from the remaining seven dogs. The mean i.v. elimination half-life (t1/2 beta) and the mean residence time (MRT) were 124 and 143 min, respectively. The mean volume of distribution at steady state (Vss) was 0.86 L/kg. Little pain was recorded upon i.m. injection; mean peak serum drug concentration (Cmax) was 4.4 micrograms/mL, the elimination half-life (t1/2el) was 247 min and the calculated bioavailability (F) was 115% of the i.v. dose. Serum CPK activity was elevated to 25-fold the pretreatment level in samples collected 4, 8 and 12 h after i.m. injection. Pain was not recorded after s.c. drug administration; the mean Cmax of 20.8 micrograms/mL was significantly greater than the corresponding value for the i.m. route, and F was 310%. The s.c. route appears to be superior to the i.m. route in terms of local tolerance and serum drug level; a 10 mg/kg SID treatment regimen is suggested for treatment of canine infections due to clindamycin sensitive bacteria. 相似文献