翻转课堂在“食品毒理学”教学中的应用     

刘怡  薛蓓  李梁  罗章  刘振东 《农产品加工．学刊》2021,(1)

由于互联网技术的不断普及,在相关学科教学中逐渐应用计算机技术等,进而形成了翻转课堂教学模式。学生通过搜寻网络资源中的相关材料,可以丰富自身的知识体系,教师通过应用网络教育资源也能够提升自身的教学水平。在课堂翻转教学模式下,师生角色发生了很大转变,学生可以充分发挥自身的主观能动性,对所学知识进行深入研究。通过阐述在“食品毒理学”教学中应用翻转课堂模式的重要性,分析“食品毒理学”教学存在的不足,进而提出翻转课堂在“食品毒理学”教学中的应用对策。  相似文献   

基因组学和蛋白组学在纳米药物毒理研究中的应用   总被引：1，自引：0，他引：1  

高昭辉  董书伟  薛慧文  荔霞  申小云  刘永明  王胜义  刘世祥  齐志明 《中国奶牛》2011,(24):34-38

近年来,纳米材料药物因其独特的生物学特性而被广泛应用于医疗领域,但其安全性问题已成为广大学者所关注的焦点。基因组学和蛋白组学的快速发展,为研究纳米药物对机体的毒性作用机理提供了相关的技术支持。本文介绍了基因组学和蛋白组学的概念及其核心技术、纳米药物毒性,并对基因组学和蛋白组学在纳米药物毒性研究中的应用进行了综述。  相似文献   

虚拟仿真实验教学系统联合问卷星在“食品毒理学”动物实验教学中的应用     

胡嘉淼  叶倩文  赖丹宁  曾绍校 《农产品加工．学刊》2022,(1)

"食品毒理学"动物实验通常需要使用较多实验动物给予毒物处理以满足课堂教学的需要,当前,飞速发展的信息时代下,各种新型教学技术手段极大地变革了高校实验课的教学形态。虚拟仿真实验教学系统和问卷星这2种新型教学手段相结合的方式,能够更加高效地辅助"食品毒理学"完成实验教学,提高教学效率,最大程度减少实验动物使用量,从而加深学生对于毒理学动物实验所倡导的3R (替代Reduction,减少Replacement,优化Refinement)原则的认识。  相似文献   

Phosphamidon induced effects on estrous cycle, ovarian, and uterine biochemical parameters in Swiss albino mice     

T.S. Sreelakshmi 《Pesticide biochemistry and physiology》2007,87(3):204-210

Phosphamidon is chemically known as phosphoric acid, 2-chloro-2-diethyl carboryl-methylvenyl-0-0-dimethyl phosphate. It is a systemic and contact insecticide with broad spectrum of activity. The present investigation was carried out to evaluate its effects on estrous cycle, ovarian, and uterine biochemical contents in albino mice. Normal virgin female Swiss albino mice of 90 days old and weighing about 20-30 g were divided into five groups. Phosphamidon was orally administered at doses 1.3, 2.6, 3.9, and 5.2 mg/kg body weight/day for 30 days consecutively. The vaginal smear and body weight were recorded daily and mice were sacrificed on 31st day. Estrous cycle was affected by showing a significant decrease in the number of estrous cycle and duration of proestrus, estrus, and metestrus in all the groups except in 1.3 mg/kg body weight/day phosphamidon treated group, and with concomitant increase in the duration of diestrus in all the treated groups. However there is a significant decrease in the body weight in all the groups except 1.3 mg/kg body weight/ day phosphamidon treated group. The deleterious effects were also reflected in the loss of weights of ovary and uterus: In mice treated with 2.6, 3.9, and 5.2 mg/kg phosphamidon showed a significant decrease in total protein and glycogen in the ovary and uterus. The response of the ovary and uterus for nucleic acid (DNA) content was significantly decreased in higher doses. The observed effects of phosphamidon may be due to imbalance in the hormone or toxic effects.  相似文献   

Emergency Management and Treatment of the Poisoned Small Animal Patient     

Justine A. Lee 《Veterinary Clinics of North America: Small Animal Practice》2013

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A retrospective evaluation of hops ingestion in 177 dogs (2005–2018)     

Jami Becker DVM  Ahna G. Brutlag DVM  MS  DABT  DABVT  Lynn Hovda RPh  DVM  MS  DACVIM  Aaron Rendahl PhD  Kelly M. Tart DVM  DACVECC 《Journal of Veterinary Emergency and Critical Care》2023,33(3):348-353

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苦荞提取物的毒理学安全性   总被引：15，自引：0，他引：15  

林汝法  王瑞  周运宁 《华北农学报》2001,16(1):116-121

通过给小鼠和大鼠投喂苦荞提取物，观察了苦荞提取物的毒理学安全性。结果表明，苦荞提取物长期连续应用，对大鼠生长发育及血液学、生化、病理指标均未见明显的不良影响，实属无毒。  相似文献   

The effects of oral magnesium hydroxide administration on rumen fluid in cattle     

Smith GW  Correa MT 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2004,18(1):109-112

This study was conducted to determine the effects of oral magnesium hydroxide administration on rumen fluid in cattle. Six lactating Holstein cows (4-7 years of age) with rumen fistulas were studied. Cattle were randomly assigned to receive boluses of magnesium hydroxide (162 g) or a powdered form (450 g dissolved in 3.5 L of water) PO daily for 3 days. Analysis of rumen fluid, blood gas tensions, and pH and measurement of serum magnesium concentrations were conducted daily. The study was discontinued after 72 hours, or sooner if rumen pH exceeded 8.0. After at least 3 weeks, the study was repeated with each cow receiving the other form of magnesium hydroxide (powder or bolus). Compared with baseline rumen pH (mean +/- SD: 6.22 +/- 0.28), magnesium hydroxide boluses caused a significant increase (P < .05) in rumen pH after 48 (7.27 +/- 0.11) and 72 (8.01 +/- 0.16) hours of administration, whereas the powdered form caused a significant increase (P < .05) in rumen pH after 24 (7.54 +/- 0.19) and 48 (8.43 +/- 0.22) hours of administration. Both the powdered and bolus forms of magnesium hydroxide decreased rumen protozoal numbers and increased methylene blue reduction times compared with baseline values. There was no change in blood pH, bicarbonate, or base excess values. Serum magnesium concentrations were significantly increased (P < .05) in cows that received the magnesium hydroxide powder. The results of this study indicate that magnesium hydroxide has a potent alkalinizing effect on rumen pH and significantly decreases rumen microbial activity.  相似文献   

Selenosis in Ruminants     

《Veterinary Clinics of North America: Food Animal Practice》2020,36(3):775-789

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Diagnostic Challenges and Guidelines Pertaining to Suspected Ruminant Intoxications     

《Veterinary Clinics of North America: Food Animal Practice》2020,36(3):509-524

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