Changes in the faecal bacterial microbiota during hospitalisation of horses with colic and the effect of different causes of colic     

Holly L. Stewart  Dipti Pitta  Nagaraju Indugu  Bonnie Vecchiarelli  Meagan L. Hennessy  Julie B. Engiles  Louise L. Southwood 《Equine veterinary journal》2021,53(6):1119-1131

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大鼠试验性乳房炎病理模型   总被引：1，自引：0，他引：1  

张书起  于洪川 《农业科学研究》2006,27(4):27-31

通过在健康大鼠一侧乳区接种200μL(107 cfu(colony forming unit)/mL)大肠杆菌悬液复制乳房炎病理模型,其模型指标有临床症状:体温、心率、呼吸频率、乳房局部温度、乳汁体细胞数、红细胞数量、白细胞数量、Hb质量分数及病理组织学变化.结果表明,按上述方法在大鼠乳房内接种大肠杆菌可复制出典型的大鼠急性乳房炎病理模型.  相似文献   

PNEUMATOSIS COLI IN A DOG     

Earl L.  Morris  DVM  MS 《Veterinary radiology & ultrasound》1992,33(3):154-157

The extensive presence of air in the submucosal area of the colon was observed on abdominal radiographs of a one-year-old female Maltese. The diagnosis of pneumatosis cystoides intestinalis (pneumatosis coli when localized to the colon) is made when radiographs demonstrate submucosal or subserosal gas accumulation of the intestinal tract. The condition usually resolves spontaneously, but the potential for complications is present.  相似文献   

成年猪结肠肥大细胞的分布     

王家鑫  李景宇  张福君  张海旺  苏建清 《中国兽医杂志》2001,37(9):7-8

成年猪结肠按常规制备石蜡切片,用甲苯胺蓝改良法显示肥大细胞.结果粘膜型肥大细胞(MMCs)主要分布于固有膜深层,不同部位结肠粘膜中MMCs的数量存在极显著差异(P＞0.01),结缔组织型肥大细胞(CTMCs)主要分布于粘膜下层且不存在数量上的区域性差异(P＞0.05).结论猪结肠MMCs的分布类型具有区域异质性特征.  相似文献   

Is a standardised approach to colopexy justified?     

M. C. Mudge  A. K. Gardner 《Equine Veterinary Education》2020,32(8):408-410

Equine colopexy techniques vary according to surgeon preference and there is no clear evidence of the superiority of any one technique. Complications secondary to colopexy are varied, but dehiscence of the colopexy site is rare, with less than 1% of horses reported to have a repeat large colon volvulus after dehiscence of the colopexy. Considerations of how and when to perform a surgical fixation of the colon to the body wall include position of the colon, length of the colopexy, and suture material and pattern. Little evidence exists regarding best practice outside of experimental studies and retrospective studies of Thoroughbred broodmares. Therefore, more work must be done to standardise a colopexy technique to apply to a broad spectrum of horses suffering from large colon volvulus and displacement.  相似文献   

Small colon obstruction by an ovarian pedicle as an acquired condition in a foal     

N. Pilati  A. E. Masciarelli  L. A. Werner  K. A. Sprayberry 《Equine Veterinary Education》2013,25(6):290-292

This report describes the clinical course and the surgical findings in a 7‐day‐old foal referred for signs of abdominal pain. The foal underwent abdominal celiotomy due to the degree of pain unresponsive to medical treatment and, upon exploration, an ovarian pedicle was found to be wrapped around the small colon. The lesion was corrected, the foal recovered well from anaesthesia, and a 4 month follow‐up revealed no other signs of abdominal pain or complications.  相似文献   

Parainguinal laparotomy as an alternative surgical approach for removal of an enterolith in the small colon of a horse     

E. J. Barrett  A. S. Munsterman 《Equine Veterinary Education》2013,25(9):442-446

This report describes the use of a parainguinal approach to the abdomen to remove an obstruction in the small colon that could not be removed using an initial ventral midline approach. The use of a parainguinal approach should be considered for removal of an obstruction in the distal portion of the small colon.  相似文献   

Okadaic Acid Toxin at Sublethal Dose Produced Cell Proliferation in Gastric and Colon Epithelial Cell Lines     

Miguel del Campo  Héctor Toledo  Néstor Lagos 《Marine drugs》2013,11(12):4751-4760

The aim of this study was to analyze the effect of Okadaic Acid (OA) on the proliferation of gastric and colon epithelial cells, the main target tissues of the toxin. We hypothesized that OA, at sublethal doses, activates multiple signaling pathways, such as Erk and Akt, through the inhibition of PP2A. To demonstrate this, we carried out curves of doses and time response against OA in AGS, MKN-45 and Caco 2 cell lines, and found an increase in the cell proliferation at sublethal doses, at 24 h or 48 h exposure. Indeed, cells can withstand high concentrations of the toxin at 4 h exposure, the time chosen considering the maximum time before total gastric emptying. We have proved that this increased proliferation is due to an overexpression of Cyclin B, a cyclin that promotes the passage from G2 to mitosis. In addition, we have demonstrated that OA induces activation of Akt and Erk in the three cells lines, showing that OA can activate pathways involved in oncogenesis. In conclusion, this study contributes to the knowledge about the possible effects of chronic OA consumption.  相似文献   

Ⅲ期结肠腺癌患者ERCC1基因多态性的检测及其与奥沙利铂化疗效果的关系     

谢美强  冼上福  庄粤蕾 《湛江医学院学报》2013,31(1):24-26

目的了解Ш期结肠腺癌患者ERCC1基因多态性及其与奥沙利铂化疗效果的关系。方法收集经病理学确诊的Ш期结肠腺癌患者85例,PCR检测ERCC1基因型;采用标准mFOLFOX6方案化疗12疗程,观察5a生存率和无疾病进展率。结果 85例中C/C基因型频率为38.8%,T/T＋C/T基因型频率为61.2%。C/C基因型患者5a生存率和无疾病进展率分别为76.5%和72.1%,T/T＋C/T基因型5年生存率和无疾病进展率分别为53.8%和46.1%,两组差异均有统计学意义（P〈0.05）。结论 ERCC1C/C基因型Ш期结肠腺癌患者对奥沙利铂化疗方案具有较好疗效。  相似文献   

Complete avulsion of the terminal mesocolon in a mare: A viable surgical option     

W. Lee  P. O. E. Mueller 《Equine Veterinary Education》2010,22(5):228-230

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