信阳地区常发鸡病及防制对策     

赵聘  薛邦玉  程孝让 《信阳农业高等专科学校学报》1999,(3)

经近五年的调查,总结出信阳地区经常发生和危害严重的十种鸡病的发病原因及防制措施,提出了常发鸡病的综合防制对策。  相似文献   

日本森林疗养研究概况及其启示     

何双玉 《湖北林业科技》2022,(1):52-56

在对日本森林疗养文献查询与阅读的基础上,通过对相关文献的分析,将日本森林疗养研究分为森林疗养效益实证研究、森林疗养基地研究及自然体验活动研究三个方面内容进行阐述,并将日本森林疗养的概念、研究内容与我国的森林康养进行比较,最后对中国森林康养产业发展做出展望。  相似文献   

Regulation mechanisms of megakaryopoiesis and platelet formation and its clinical application     

CHEN Zi-xing 《园艺学报》2019,35(10):1901-1908

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Von Hippie-Lindau病1例临床分析     

宁显宾  赵长福  罗祺 《吉林林学院学报》2010,(1):56-58

目的探讨Von Hipple—Lindau病的诊断及治疗．方法报道VonHippie—Lindau病1例,总结延髓血管母细胞瘤手术的经验教训,结果患者于术后1个月临床死亡．结论通过详细的综合检查及治疗,并及时总结延髓血管母细胞瘤手术方法,从而提高对该病的诊治水平．  相似文献   

针刺疗法治疗血管性痴呆的临床研究进展          下载免费PDF全文

黎帅  黄桂兰  谭洁  张泓 《勤云标准版测试》2016,36(12):91-95

血管性痴呆（vascular dementia,VD）是由各种脑血管病引起脑组织损害而产生的痴呆,它是仅次于阿尔茨海默病的常见痴呆类型。针刺疗法对血管性痴呆的认知功能及社会活动功能康复有积极作用,临床应用广泛。本文综述中文数据库中近五年相关针刺疗法治疗血管性痴呆临床文献报道,科学评价针刺疗法的优势和不足,以期为临床治疗血管性痴呆提供参考。  相似文献   

CD147 monoclonal antibody-mediated nanoparticles for gene therapy to target lung cancer cells     

WU Fei-long  KONG Qing-lei  CAI Song-wang  YE Zhi-qiang 《园艺学报》2016,32(9):1562-1567

AIM: In this study, CD147 antibody was used to carry out targeted modification of nanoparticles for protein kinase Cε (PKCε)-siRNA gene therapy to target lung cancer cells. The inhibitory effects of the nanoparticles on the proliferation and invasion of the lung cancer cells were observed. METHODS: The magnetic nanoparticles targeting CD147 protein were assembled as gene vector. The expression of CD147 in the lung cancer cells was observed under laser scanning confocal microscope. The cells were divided into CP group, CN group and LP group as the experimental groups. Targeted nanoparticles were used as CA group. Non-transfected cells were used as control group. The cell transfection was carried out with 250 ng plasmids/well in 6-well plate. The effect of nanocontrast agent on the cell endocytosis was observed under laser scanning confocal microscope. The mRNA expression of PKCε was detected by RT-qPCR. The protein expression of Ki67, MMP3, PKCε, Wnt1 and GAPDH was determined by Western blot. The cell proliferation ability was detected with colony formation assay. The cell invasion ability was detected by Transwell method. RESULTS: The expression of CD147 protein in the human lung cancer A549 cells was confirmed by immunofluorescence staining. The endocytosis of siRNA into the A549 cells in CP group was observed with the highest efficiency as compared with CN group and LP group. The relative mRNA expression of PKCε in the A549 cells of CP group, CN group, LP group and CA group were (9.76±0.18)%, (98.51±0.32)%, (99.17±0.16)% and (99.68±0.11)%, respectively. The difference between CP group and control group was statistically significant (P<0.05). No significant difference among CN group, LP group and control group was observed. The protein expression of PKCε, Ki-67, MMP3 and Wnt1 in CP group was significantly reduced, and the protein expression levels among CN group, LP group and control group had no significant difference. The colony number in CP group was significantly smaller than that in control group (P<0.05). The effective colony numbers in CN group, LP group and CA group had no significant difference as compared with control group. The number of the invading cells in CP group was significantly less than that in control group (P<0.05). The numbers of the invading cells in CN group, LP group and CA group had no significant difference as compared with control group. CONCLUSION: Nanogene vector targeting CD147 can carry PKCε-siRNA to conduct gene therapy efficiently on the lung cancer cells to achieve effective inhibitory effects on the proliferation and invasion of the lung cancer cells.  相似文献   

Efficacy of itraconazole as a combined continuous/pulse therapy in feline dermatophytosis: preliminary results in nine cases   总被引：1，自引：0，他引：1  

Colombo S  Cornegliani L  Vercelli A 《Veterinary dermatology》2001,12(6):347-350

This study evaluated the efficacy of itraconazole as a combined continuous/pulse therapy for feline dermatophytosis. Nine cats with dermatophytosis caused by Microsporum canis were treated with itraconazole at 10 mg kg(-1) orally once daily for 28 days and then on an alternate week regimen (1 week off, 1 week on) at the same dosage. Cats were re-evaluated by physical examination and fungal culture at days 28, 42, 56 and 70 if necessary. Treatment was stopped when two consecutive negative fungal cultures were obtained. Eight cats were cured after 56 days, with two negative cultures obtained at days 28 and 42. In one case, a positive culture was obtained at day 28, but negative cultures were achieved at days 42 and 56. This protocol appears to be effective in the treatment of feline dermatophytosis, although these preliminary results should be confirmed by a controlled study.  相似文献   

Management of femoral artery thrombosis in an immature dog     

Kathy C. Tater  DVM    Sharon Drellich  DVM  DACVECC    Kathy Beck  DVM  DACVR 《Journal of Veterinary Emergency and Critical Care》2005,15(1):52-59

Objective: To report a case of femoral artery thrombosis and its medical management in a young dog. Case summary: A 13‐week‐old, female Boxer puppy presented with hind limb paralysis after an abdominal crush injury. A left femoral artery thrombus was identified on ultrasound. No spinal trauma was visualized in imaging studies. Clinical management of arterial thrombosis in a 13‐week‐old puppy with streptokinase and dalteparin therapy is described. New or unique information provided: This paper describes an unusual presentation of arterial thrombosis. The medical management with streptokinase and dalteparin is also out of the ordinary. Images that document the development of compensatory circulation around the thrombosed vessel are included. Additionally, this paper also documents the altered development that occurred in this immature dog after the thrombotic event.  相似文献   

Effect of thyroid hormone supplementation on survival of euthyroid dogs with congestive heart failure due to systolic myocardial dysfunction: a double-blind, placebo-controlled trial     

Tidholm A  Falk T  Gundler S  Svensson H  Ablad B  Sylvén C 《Research in veterinary science》2003,75(3):195-201

Nineteen euthyroid dogs of 12 breeds with echocardiographic signs of dilated cardiomyopathy (DCM) and radiographic and clinical signs of congestive heart failure (CHF) were evaluated in a randomised, double-blind, and placebo-controlled study. The dogs received either thyroxine or placebo as an adjunct to digoxin, furosemide and propranolol. The group assignment of individual dogs and serum concentrations of thyroid hormones remained unknown to owners and investigators during the entire study period. Dogs were evaluated clinically and with electrocardiography (ECG), thoracic radiography, echocardiography and measurement of total thyroxine (tT4) and thyroid stimulating hormone (TSH) before beginning of the trial, and then one week, 2 months, 6 months and yearly after initial examination, and, when applicable, at the time of euthanasia. End-point of the study was euthanasia (n = 17) due to severe congestive heart failure or sudden death (n = 2). Survival times ranged from 17 to 1030 days (median 187 days) in the placebo group, and from 18 to 1000 days (median 73 days) in the treatment group. There was no statistically significant difference in survival times between the treatment group and the placebo group (p = 0.46). Post mortem and histopathologic examinations revealed the attenuated wavy fiber type of DCM in 11 dogs, and myocardial infarcts, arteriosclerosis and chronic valvular disease in one dog. In conclusion, there was a wide range in survival times of dogs treated with digoxin, furosemide and propranolol. Adding thyroid hormones to the treatment did not significantly influence survival.  相似文献   

Confirmation of the Prophylactic Value of Paromomycin in a Natural Outbreak of Caprine Cryptosporidiosis     

Johnson EH  Windsor JJ  Muirhead DE  King GJ  Al-Busaidy R 《Veterinary research communications》2000,24(1):63-67

Veterinary Research Communications -  相似文献