王若光教授治疗子宫内膜异位症致不孕临床经验          下载免费PDF全文

陈林  王若光  蒋文君  邱四君 《勤云标准版测试》2017,37(12):1345-1348

王若光教授认为子宫内膜异位症是从多方面、多环节影响卵泡的发育和成熟、排卵、受精、子宫内膜容受性、胚胎着床和发育导致不孕不育。王教授认为其中医主要病机为“虚、瘀、痛”,实质为本虚标实,本虚为脾肾两虚,黄体不足,胞脉失于濡养不荣则痛,标实为湿瘀夹杂,胞脉阻滞不通则痛,治疗上提倡中西医结合治疗,中药三期论治：经期重在活血化瘀、调理气血、利水化湿、软坚散结、抗炎为大法;经后期滋阴助阳、宁心益肾健脾、暖宫促孕、促排卵,排卵后补充孕激素;经前期以补益脾肾兼理气,以“调经助孕,改善卵巢功能”为治疗大法,临床疗效显著。  相似文献   

4,4'-Dinitrocarbanilide (DNC) concentrations in egg shells as a predictor of nicarbazin consumption and DNC dose in goose eggs     

Stahl RS  VerCauteren KC  Kohler D  Johnston JJ 《Pest management science》2003,59(9):1052-1056

Nicarbazin is being investigated as an infertility agent for the control of non-migratory Canada geese (Branta canadensis L) populations. Nicarbazin is presently registered for use as a coccidiostat for poultry. Geese fed sufficient quantities of nicarbazin will lay non-viable eggs. We established nicarbazin consumption by measuring the concentration of a component of the formulation, 4,4'-dinitrocarbanilide (DNC) in the egg contents (yolk, albumin) in non-viable eggs. To estimate the nicarbazin consumption of birds that laid viable eggs (eggs that hatched or contained an embryo), a high-performance liquid chromatography method was developed to measure the concentration of DNC in egg shells. A statistically significant correlation was established using linear regression between the mean concentrations of DNC in the egg shell and in the egg contents in non-viable eggs. Viable eggs were estimated to contain lower levels of DNC than non-viable eggs. DNC concentrations in both the egg contents and the egg shell increased with increases in nicarbazin dose in feed. Our method allows for the estimation of nicarbazin consumption and DNC dose in eggs under field conditions, which is important in developing an effective infertility agent for over-abundant non-migratory goose populations.  相似文献   

Listeric Infections in Humans and Animals in the Indian Subcontinent: A Review     

Malik SV  Barbuddhe SB  Chaudhari SP 《Tropical animal health and production》2002,34(5):359-381

Listeriosis is an important bacterial zoonosis caused by the intracellular pathogen Listeria monocytogenes. The disease has been reported in animals from the Indian subcontinent, usually in the form of sporadic cases but occasionally as outbreaks. Cases of listeriosis arise mainly from the ingestion of contaminated food. Listeriosis has been reported to cause encephalitis, abortion, mastitis, repeat breeding and endometriosis in animals. Listeric infections occur in children and women with a poor obstetric history. The epidemiological aspects and pathogenesis of listeriosis in animals and humans are not yet fully understood. This review offers comprehensive information on experimental studies and field cases in animals and on cases of human listeriosis. There are also sections on isolation from foods, diagnosis and treatment in humans and animals.  相似文献   

Incidence of infertility in dairy cows     

K Roine  H Saloniemi 《Acta veterinaria Scandinavica》1978,19(3):354-367

The incidence of anoestrus, suboestrus, delayed ovulation, cystic ovaries, repeat breeder cows, endometritis and other forms of infertility was studied in 283 herds over a period of eight years (2,304 cases). The total incidence of infertility (0.111 cases per cow per year) varied significantly from year to year. The peak of the seasonal variation occurred in December-April and did not correspond with the seasonal variation in calving. Both the size of herd and the type of housing affected the incidence of infertility, but the differences were great in respect of the various diagnoses. The incidence of ketosis by herd correlated significantly with the incidence of infertility by herd.  相似文献   

Total antioxidant capacity and protein peroxidation intensity in seminal plasma of infertile and fertile dogs     

Anna Domoslawska  Slawomir Zdunczyk  Monika Franczyk  Marta Kankofer  Tomasz Janowski 《Reproduction in domestic animals》2019,54(2):252-257

The aim of this study was to evaluate the total antioxidant capacity and protein peroxidation intensity in seminal plasma of infertile and fertile dogs. The study was conducted on 10 infertile and 10 fertile dogs of various breeds. Infertility was defined as conception failure at least three matings with different bitches. Semen was collected by manual manipulation. The sperm concentration and motility parameters were evaluated using CASA Hamilton Thorne, Vers. IVOS 12.3. The morphology of spermatozoa and the percentage of live and dead sperm cells were assessed microscopically, total antioxidant capacity and the content of SH‐groups in seminal plasma were determined spectrophotometrically, the contents of protein peroxidation markers in seminal plasma, bityrosine and formylokinurenine, were determined using spectrofluorimetric methods. Sperm concentration and total sperm count were significantly (p < 0.05) lower in infertile dogs than in fertile dogs (99.92 ± 3 0.05 × 10⁶/ml vs. 282.07 ± 48.27 × 10⁶/ml; 214.19 ± 114.74 × 10⁶ vs. 747.57 ± 210.94 × 10⁶, respectively). The percentage of spermatozoa with normal morphology and the most determined motility parameters differed significantly (p < 0.05) between both groups. The mean values of total antioxidant capacity in the seminal plasma were significantly (p < 0.05) lower (19.95 ± 20.94 vs. 25.66 ± 23.18 µmol/g protein), whereas the mean contents of bityrosine and formylokinurenine in seminal plasma were significantly (p < 0.05) higher in infertile dogs than in fertile dogs (3.71 ± 4.83 µg/mg protein vs. 1.55 ± 2.00 µg/mg protein and 0.37 ± 0.45 µg/mg protein vs. 0.14 ± 0.08 µg/mg protein, respectively). In conclusion, the obtained results suggest that the poor semen quality and infertility in dogs could be associated with lowered total antioxidant capacity and increased protein peroxidation in seminal plasma as a consequence of oxidative stress.  相似文献   

两种不育剂药饵对黄毛鼠的适口性比较     

秦姣  刘全生  舒骏  郭明昉 《广东农业科学》2011,38(20)

鼠药的适口性是决定鼠害控制效果的关键因素之一。采用单只饲喂法,以稻谷为基饵,分别测定了0.005%炔雌醚和米非司酮药饵对黄毛鼠的适口性。结果表明,黄毛鼠对炔雌醚药饵平均摄食系数显著低于米非司酮;雌雄鼠对炔雌醚和米非司酮药饵的摄食差异显著。炔雌醚显著降低了雌雄鼠对药饵的摄食量,且雄鼠摄食量少于雌鼠。米非司酮提高药饵对雌鼠的适口性,但不影响对雄鼠的适口性;黄毛鼠在处理时间内对药饵的摄食量存在显著变化,雌雄鼠第1 d对炔雌醚药饵和基饵摄食量无显著差异,第2、3 d对炔雌醚药饵摄食量显著少于基饵;雌鼠第1 d对米非司酮药饵和基饵摄食无显著差异,第2、3 d取食药饵显著多于基饵,雄鼠在用药第1 d即表现出对米非司酮药饵的偏好,但随后2 d对基饵和药饵摄食量差异不显著。0.005%米非司酮的稻谷对黄毛鼠具有很好的适口性,而炔雌醚药饵配制有待改善,如增加香味剂、甜味剂等提高其适口性。  相似文献   

鼠类不育剂在我国的研究与应用     

杨新根  王庭林  宁振东  朱文雅  邹波  侯玉  常文英  刘汉宇 《山西农业科学》2011,39(8):922-924

对鼠类的不育防控作为鼠害综合治理的一个新兴领域,被认为是比传统毒杀方法更有发展潜力的一种技术。鼠类不育剂由于其经济、安全、作用周期长、对环境没有副作用等优点受到了国内外有关专家的大力推荐。通过论述鼠类不育剂在中国的研究情况与应用进展,提出了在山西省对鼠类不育剂的应用技术进行试验、集成与推广的必要性。  相似文献   

Nitrite exposure may induce infertility in mice     

Shanshan Wu  Sang Hu  Wenjuan Fan  Xiaojing Zhang  Haili Wang  Chaojie Li  Jinbo Deng 《Journal of toxicologic pathology》2022,35(1):75

In the present study, we investigated the potential of nitrite exposure to induce infertility in mice. Adult female C57BL/6J mice were randomly divided into control and nitrite exposure groups. Subsequently, the rate of mouse infertility was calculated, and pathological changes in ovarian tissues were examined using hematoxylin and eosin staining. In addition, TUNEL staining, immunofluorescent labeling, and western blotting were performed to assess cell apoptosis and oxidative stress response in ovarian tissues from various groups. We observed that nitrite exposure could induce infertility (p<0.05) in mice. High-dose nitrite exposure caused infertility in a time-dependent manner, and two-round exposure induced higher infertility than that one-round exposure (p<0.01). In addition, a higher number of atretic follicles were detected in the ovaries of nitrite-exposed groups than in the control group. Furthermore, TUNEL-positive cells were observed in granulosa cells of atretic follicles, and overexpression of caspase 8, c-Fos, and inducible nitric oxide synthase (iNOS) was detected in ovaries after nitrite exposure (p<0.01), suggesting that cell apoptosis and oxidative stress response were induced following nitrite exposure. Collectively, these findings suggest that nitrite exposure can induce mouse infertility in a time-dependent manner. Oxidative stress response and cell apoptosis are involved in mediating nitrite-induced infertility.  相似文献   

猪副粘病毒感染的初步诊断和病毒分离   总被引：10，自引：2，他引：10  

吴祖立  高诚  叶陈梁  刘永德  马帝 《上海交通大学学报(农业科学版)》2002,20(1):67-68

在临床症状复杂的不同猪群中 ,分离出 4株副粘病毒。该病毒能凝集鸡红细胞 ,其血凝性能被鸡新城疫标准血清抑制。病毒能在鸡胚中生长繁殖。电镜观察不是冠状病毒而是副粘病毒。该病毒能引起猪的腹泻、呼吸急促、繁殖障碍、神经症状和体温升高等临床症状。  相似文献   

长沙市男性不育症患者睾丸体积与中医体质类型分析          下载免费PDF全文

高瑞松  林群芳  黄培  任孝伟  周青 《勤云标准版测试》2016,36(6):85-88

目的 通过对长沙市344例男性不育症患者进行中医体质的问卷调查,探讨男性不育症患者体质分布的特点及其精液质量、睾丸大小与中医体质的关系,分析常见病因对中医体质的影响。方法 根据中华中医药学会《中医体质分类与判定》（ZYYXH/T157-2009）对344例不育男性进行体质辨识,结合临床资料进行统计分析,讨论中西医结合治疗的方法和思路。结果 344例男性不育患者中平和体质占17.4%,单一偏颇体质（为一种偏颇体质者）占25.6%,混合偏颇体质占57.0%。总体体质类型前10位依次为平和质（17.4%）、湿热痰湿质（14.2%）、阳虚气虚质（9.59%）、湿热质（8.43%）、阳虚痰湿质（6.69%）、痰湿质（5.81%）、气虚湿热质（5.81%）、气虚质（4.94%）、阳虚质（4.36%）、气郁气虚质（3.49%）。结论 从单一体质类型看除平和质外,湿热质和气虚质是不育患者的主要体质类型;复合类型中,虽然各复合型相对分散,但仍然表现以湿热复合类为主要特征,而阳虚、气虚、痰湿复合类次之的分布特征;而总体阴虚质、特禀质、血瘀质及其复合类都很少见;不育症患者不同睾丸体积的中医体质分布差异具有统计学意义。  相似文献