SCSMRD: A database for single-cell skeletal muscle regeneration          下载免费PDF全文

FENG Xi-kang  XIE Chun-di  LI Yong-yao  WANG Zi-shuai  BAI Li-jing 《农业科学学报》2023,22(3):864-871

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Identification and functional prediction of long intergenic noncoding RNAs in fetal porcine longissimus dorsi muscle          下载免费PDF全文

Cen-cen LI  Shu-long YU  Hai-feng REN  Wei WU  Ya-ling WANG  Qiu HAN  Hai-xia XU  Yong-jie XU  Peng-peng ZHANG 《农业科学学报》2021,20(1):201-211

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冷环境中解偶联蛋白对动物体温的调节作用     

柴艳  ;李琦华  ;田允波  ;文生萍  ;陈保定  ;葛长荣  ;贾俊静 《家畜生态》2008,(3):104-108

解偶联蛋白属线粒体内膜载体蛋白,存在动物体的棕色脂肪组织（brown adipose tissue,BAT）、白色脂肪组织（white adipose tissue,WAT）、骨胳肌以及各种器官中。这些组织器官是哺乳动物及禽类非颤抖产热（NST）及其它产热作用的主要点位,对动物的体温维持和能量平衡调节起重要作用。  相似文献   

Effect of dietary fish oil intake on ubiquitin ligase expression during muscle atrophy induced by sciatic nerve denervation in mice     

Yusuke Komiya  Chiaki Kobayashi  Naoyasu Uchida  Shohei Otsu  Tatsuki Tanio  Issei Yokoyama  Jun Nagasao  Keizo Arihara 《Animal Science Journal》2019,90(8):1018-1025

Dietary fish oil intake improves muscle atrophy in several atrophy models however the effect on denervation‐induced muscle atrophy is not clear. Thus, the aim of this study was to investigate the effects of dietary fish oil intake on muscle atrophy and the expression of muscle atrophy markers induced by sciatic nerve denervation in mice. We performed histological and quantitative mRNA expression analysis of muscle atrophy markers in mice fed with fish oil with sciatic nerve denervation. Histological analysis indicated that dietary fish oil intake slightly prevented the decrease of muscle fiber diameter induced by denervation treatment. In addition, dietary fish oil intake suppressed the MuRF1 (tripartite motif‐containing 63) expression up‐regulated by denervation treatment, and this was due to decreased tumor necrosis factor‐alpha (TNF‐α) production in skeletal muscle. We concluded that dietary fish oil intake suppressed MuRF1 expression by decreasing TNF‐α production during muscle atrophy induced by sciatic nerve denervation in mice.  相似文献   

Coding sequences of sarcoplasmic reticulum calcium ATPase regulatory peptides and expression of calcium regulatory genes in recurrent exertional rhabdomyolysis     

Stephanie J. Valberg  Kaitlin Soave  Zoë J. Williams  Sudeep Perumbakkam  Melissa Schott  Carrie J. Finno  Jessica L. Petersen  Clara Fenger  Joseph M. Autry  David D. Thomas 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2019,33(2):933-941

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Impact of alpha‐tocopherol deficiency and supplementation on sacrocaudalis and gluteal muscle fiber histopathology and morphology in horses     

Lauren Bookbinder  Carrie J. Finno  Anna M. Firshman  Scott A. Katzman  Erin Burns  Janel Peterson  Anna Dahlgren  Brittni Ming‐Whitfield  Shelby Glessner  Amanda Borer‐Matsui  Stephanie J. Valberg 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2019,33(6):2770-2779

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骨骼肌肌浆网在收缩潜伏期内的超微结构形态变化   总被引：2，自引：0，他引：2  

姜永良  杨勇骥  郑尊  邵晓良  夏金辉 《浙江大学学报(农业与生命科学版)》1998,(Z1)

采用双向红外线探测器－计算机控制的电刺激与超低温快速冷冻固定同步技术对被电刺激后的骨骼肌作快速冷冻固定,采用透射电镜对电刺激后０．８ｍｓ,５．６ｍｓ,８．４ｍｓ及完全舒张时的蟾蜍腓肠肌超微结构变化进行了对比研究。骨骼肌组织在电刺激后０．８ｍｓ,５．６ｍｓ及８．４ｍｓ时发现肌浆网的前端,膜产生两个圆孔,而在骨骼肌处于全舒张时,肌浆网膜并无此形态结构。骨骼肌兴奋－收缩偶联发生时,发现肌浆网近Ｔ－管端的膜产生两个圆孔,而骨骼肌处于全舒张时,肌浆网膜也无此形态结构;骨骼肌收缩时出现的肌浆网膜小孔是否与肌浆网内某种物质（引起钙离子释放的某种未知物质？钙流？）在肌组织收缩时的转运或释放有关？  相似文献   

Effects of omega-7 palmitoleic acids on skeletal muscle differentiation in a hyperglycemic condition     

Yayoi TOKUNAGA  Hitomi YOSHIZAKI  Akiyo TORIUMI  Ritsuko KAWAHARADA  Chisato ISHIDA  Masatoshi HORI  Akio NAKAMURA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(9):1369

Maternal obesity and diabetes are known to be involved in fetal myogenesis, but the later stages of myogenesis are not well understood. In this study, we investigated the influence of a hyperglycemic environment on L6 skeletal myoblast differentiation and the function of omega-7 palmitoleic acids. Exposure to a high concentration of glucose (25 mM) in high-glucose culture medium (HG) increased the expression of myogenic genes (MyoD, Myogenin, MRF4, Myhc2x, and Myhc2a) and the synthesis of myosin. HG also activated the PI3K/AKT pathway revealed muscle cell differentiation. Furthermore, the levels of reactive oxygen species (ROS) and an inflammatory cytokine (Tnfaip3; tumor necrosis factor alpha-induced protein 3), which are crucial for the growth and differentiation of skeletal muscle, were increased by HG. Palmitoleic acids suppressed the expression levels of myogenic regulatory genes and increased the expression level of a cell proliferation-related gene (Pax3). Trans-palmitoleic acid and eicosapentaenoic acid (TPA and EPA) increased the phosphorylation level of MAPK/ERK1/2 and downregulated ROS generation and Tnfaip3 expression. In contrast, cis-palmitoleic acid inactivated MAPK/ERK1/2, leading to increased ROS generation. In conclusion, a hyperglycemic environment mediated by HG induced excessive muscle differentiation. Palmitoleic acids inhibited myoblast differentiation by downregulating muscle-specific genes. Moreover, trans-palmitoleic acids may have beneficial antioxidant and/or anti-inflammatory effects in cells.  相似文献   

Real-time RT-qPCR assay to detect sequences in the Piscine orthoreovirus-1 genome segment S1 associated with heart and skeletal muscle inflammation in Atlantic salmon     

Ahmed Siah  Emilie Knutsen  Zina Richmond  Meghan Mills  Kathleen Frisch  James F. F. Powell  Øyvind Brevik  Henrik Duesund 《Journal of fish diseases》2020,43(8):955-962

During the last decade, Piscine orthoreovirus was identified as the main causative agent of heart and skeletal muscle inflammation (HSMI) in Atlantic Salmon, Norway. A recent study showed that PRV-1 sequences from salmonid collected in North Atlantic Pacific Coast (NAPC) grouped separately from the Norwegian sequences found in Atlantic Salmon diagnosed with HSMI. Currently, the routine assay used to screen for PRV-1 in NAPC water and worldwide cannot differentiate between the two groups of PRV-1. Therefore, this study aimed at developing a real-time polymerase chain reaction (RT-qPCR) assay to target the PRV-1 genome segments specific for variants associated with HSMI. The assay was optimized and tested against 71 tissue samples collected from different regions including Norway, Chile and both coast of Canada and different hosts farmed Atlantic Salmon, wild Coho Salmon and escaped Atlantic Salmon collected in British Columbia, West Coast of Canada. This assay has the potential to be used for screening salmonids and non-salmonids that may carry PRV-1 potentially causing HSMI.  相似文献   

Gene expression analyses in malformed skeletal structures of gilthead sea bream (Sparus aurata)     

Natlia Riera‐Heredia  Emilio J. Vlez  Joaquim Gutirrez  Isabel Navarro  Encarnacin Capilla 《Journal of fish diseases》2019,42(8):1169-1180

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