IMAGING DIAGNOSIS —ANTEMORTEM DETECTION OF OLIGODENDROGLIOMA “CEREBROSPINAL FLUID DROP METASTASES” IN A DOG BY SERIAL MAGNETIC RESONANCE IMAGING          下载免费PDF全文

Mariana Vigeral  R. Timothy Bentley  Nicholas J. Rancilio  Margaret A. Miller  Hock Gan Heng 《Veterinary radiology & ultrasound》2018,59(4):E32-E37

An English Bulldog underwent radiation therapy of an intracranial, left lateral ventricle mass. Following resolution of the primary mass, an intraventricular fourth ventricle lesion developed. Subsequently, multiple lesions developed from the cervical central canal and leptomeninges. Serial magnetic resonance imaging documented the propagation of lesions along the cerebrospinal fluid (CSF) pathways, known as “CSF drop metastasis.” Histopathology confirmed multifocal intraventricular and leptomeningeal oligodendroglioma. Oligodendroglioma should be included in the differential diagnosis for an intraventricular tumor exhibiting apparent CSF drop metastasis.  相似文献   

Relationships among neuroscore,magnetic resonance imaging features,and intracranial pressure in sheep affected by slow‐growing brain lesions          下载免费PDF全文

Maria A. Evangelisti  Roberta Deiana  Valentino Melosu  Giovanni P. Burrai  Isabella Ballocco  Antonio Varcasia  Antonio Scala  Maria L. Manunta 《Veterinary radiology & ultrasound》2018,59(3):305-311

Diagnosing high intracranial pressure by clinical and diagnostic imaging is particularly challenging for chronic or slow‐growing lesions. The aim of this prospective case‐control study is to determine whether the neuroscore and brain magnetic resonance imaging (MRI) are related to the direct measurement of intracranial pressure in sheep affected by intracranial slow‐growing lesions due to chronic cerebral coenurosis (Coenurus cerebralis). Seventeen affected and 10 control sheep were included. All animals underwent a neurological examination, MRI of the brain, and direct measurement of intracranial pressure. The severity of clinical signs and MRI findings were scored. Data were statistically analyzed. The invasive intracranial pressure value was higher in affected animals. A severely altered neuroscore is related to an increased intracranial pressure beyond the normal threshold (P < 0.05). The volume of the calvarium was larger in affected animals than in control animals (P = 0.0001) and was positively influenced by the presence and volume of the parasitic cyst (r = 0.7881, P < 0.01). Several degrees of deviation and deformation of both the ventricular system and brain parenchyma were detected by MRI. Subjective MRI findings were not associated with intracranial hypertension. In conclusion, this study shows that in sheep affected by slow‐growing lesions, severe alterations in the neuroscore and the results of objective MRI are related to an increased intracranial pressure beyond the normal threshold.  相似文献   

Abrogation of fluid suppression in intracranial postcontrast fluid‐attenuated inversion recovery magnetic resonance imaging: A clinical and phantom study          下载免费PDF全文

Peter J. Dickinson  Sarah Jones‐Woods  Derek D. Cissell 《Veterinary radiology & ultrasound》2018,59(4):432-443

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Brain Awareness and Conflict in Veterinary Medical Practice: What Happens and How to Deal with It     

《Veterinary Clinics of North America: Small Animal Practice》2019,49(3):575-586

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Effect of methotrexate exposure at late gestation on development of telencephalon in rat fetal brain     

Ayano HIRAKO  Satoshi FURUKAWA  Takashi TAKEUCHI  Akihiko SUGIYAMA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2016,78(2):213-220

Pregnant rats were treated with 30 mg/kg of methotrexate (MTX) on gestation day (GD) 16, and fetal brains were examined time-dependently. On GD 20, the appearance of the telencephalon in the MTX group was different from that in the control group, and the major axis of the telencephalon of the MTX group was shortened, compared to that of the control group. In the sagittal section of the telencephalon in the MTX group on GD 20, histopathological findings of deformation and narrowing of the cerebral ventricle, the disturbance of the arrangement of the marginal cell layer of subventricular zone (SVZ) and thickening of telencephalic wall, cortical plate and ventricular zone (VZ)/SVZ were possibly attributable to neuronal migration disorders by MTX. Through all the experimental period, few pyknotic cells or TUNEL-positive cells were observed in the VZ/SVZ of the telencephalic wall and striatum in the control group. On the other hand, in the VZ/SVZ of the telencephalic wall and striatum in the MTX group, pyknotic cells or TUNEL-positive cells were observed on GD 17, and they increased significantly on GD18 and then decreased to the control levels from GD 19 onward. The phospho-Histone H3-positive rate decreased remarkedly in the VZ/SVZ of the telencephalic wall and striatum of the MTX group on GDs 17 and 18, compared to the control group, but they recovered on and after GD 19. These results suggested that there was a high possibility that development of the telencephalon in this period required strong folic acid.  相似文献   

Ballistic trauma to the axial skeleton in 13 animals     

Jessica Linder DVM  Jonathon Daniel DVM  Francesca Vadurro  Leonel Londono DVM  DACVECC  Michaela Beasley DVM  MS  DACVIM  Gabriel A. Garcia DVM  DACVIM  Sheila Carrera-Justiz DVM  DACVIM 《Journal of Veterinary Emergency and Critical Care》2023,33(3):332-336

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沙棘油口服液对运动训练小鼠脑组织自由基代谢和超微结构影响的实验研究   总被引：3，自引：0，他引：3  

熊正英  刘小杰  唐量 《沙棘》2004,17(2):14-17

目的 :通过测定运动小鼠大脑超氧化物歧化酶 (SOD)活性、丙二醛 (MDA)含量 ,观察超微结构变化 ,探讨服用沙棘油对小鼠能力影响的生物化学机制。方法 :70只雄性 ICR小鼠随机分为六组 :安静对照组、安静沙棘组、训炼即刻组、训练即刻沙棘组、训练恢复 2 4 h组和训练恢复 2 4 h沙棘组。经过 6周游泳耐力训练后进行一次力竭性游泳 ,分析比较了各组脑组织 SOD、MDA等指标的变化并对各组脑细胞超微结构进行了电镜观察。结果 :各组 SOD活性除安静对照组与相应沙棘组 ,训练即刻沙棘组与训练恢复沙棘组间无显著差异外 (P>0 .0 5 ) ,其余各组间均有显著差异 (P<0 .0 5 ) ;MDA含量除训练即刻组与相应沙棘组及恢复组间无显著差异外 (P>0 .0 5 ) ,其余各组间均有显著差异 (P<0 .0 5 ) ;沙棘组脑细胞中线粒体、肌浆网、肌丝等结构均比相应对照组完整 ,病变程度比对照组轻。结论 :沙棘油能提高脑组织抗自由基氧化的能力 ,同时还对脑细胞超微结构具有明显保护作用 ,减轻运动对脑细胞的损伤程度并可延长运动至疲劳的时间。  相似文献   

A Realistic Neural Network on Cerebral Learning-memory   总被引：1，自引：0，他引：1  

LIU Mao lin 《保鲜与加工》2002,(12):110-113

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Research Methods of Brain-computer Interface Technology     

HE Qing hu  PENG Cheng lin  WU Bao ming 《保鲜与加工》2002,(12):106-109

Brain computer interface(BCI) is an EEG based communication and control system between human and computer or other electric devices, which does not depend on the brain's normal output channels of peripheral nerves and muscles. It is a novel kind of human interface, may have applications in rehabilitation, control and other fields. The developming speed of brain computer research in recent years is high. Methods of how to use P300, SSVEP, ERS/ERD, SCP, spontaneous EEG and implanted electrode to realize BCI are introduced. Characteristic and limitation of different methods are discussed. Status, problems and application prospects of BCI technology are also included.  相似文献   

Impact on Brain Wave Rhythm and Learning Efficiency by Color Temperature of Artificial Light Sources   总被引：3，自引：0，他引：3  

YAN Yong-hong  YAN Ning  GUAN Yang  ZENG Heng-zhi 《保鲜与加工》2012,(1):76-79

This experiment tests the change rate of students α & β brain waves under different illuminance levels combining with three color temperatures (CCTs) to indicate the influence of light spectrum on human physiological rhythm.The result shows that the brain electrical activities have significant differences under various CCTs and illuminance levels.The excitement and sensitivity of brain are roughly proportional to the light CCTs and illuminance. Brain electrical activities are more sensible to high CCT illuminations. Keeping mental work in the same time period with the same study intensities, brain fatigue comes earlier and stronger in excitable state at high illuminace and high CCT illumination than in peacful state at low illuminance and low CCT illumination.This situation leads to the learning efficiency of students decreased sharply.An interesting phenomena is that when working in low illuminance and low CCT environment, learning efficiency of students rises with time passing by.That indicates this kind of lighting environment may lead to awake effect of brain. In some environments which have the same illuminance levels with different CCTs that bring about the similar brain activities, learning efficient change rates are different because of the diversity of light spectrum which may induce the different stimulus intensity.Further research work is needed to explain this phenomenon.This experiment points out that the long-term mental workload character during the process of study and comprehensive effect of time accumulationmust be seriously considered in classroom lighting design.  相似文献