全自动换血治疗G-6-PD缺陷症并发急性溶血的疗效观察     

邝文英  郑丽萍  汪伟山  黄辉文 《湛江医学院学报》2003,21(5):446-448

目的 :观察全自动换血治疗危重G 6 PD缺陷症并发急性溶血的疗效。方法 :对 1 0例危重G 6 PD缺陷症并发急性溶血采用全自动换血治疗。结果 :总胆红素由换血前 (5 33.1 4± 1 1 5 .6 5 ) μmol/L下降至换血后 (2 95 .5 0± 88.5 1 )μmol/L ,换出率是 4 4 .5 7% ,血红蛋白增加 34.1 2 % ,红细胞增加 4 3.30 % ,换血过程无明显不良反应。结论 :全自动换血是抢救危重G 6 PD缺陷症并发急性溶血的简单、实用、安全、有效的方法  相似文献   

反刍动物的葡萄糖营养与调控     

王春林  陈喜斌 《中国畜牧兽医》2001,28(5):2-4

综述了葡萄糖在反刍动物营养代谢中的特殊功能 ,阐述了当前葡萄糖营养调控研究的新进展  相似文献   

Selection for chip quality and specific gravity of potato clones: possibilities for early generation selection     

K. M. Louwes  A. E. F. Neele 《Potato Research》1987,30(2):241-251

Summary Ten cultivars contrasting in chip quality were grown in the field and in the glasshouse to evaluate three different methods for chip quality assessment. Specific gravity was also measured. The glasshouse culture simulated growth of seedlings and the field culture represented growth of advanced breeding lines. Differences between cultivars for chip quality and specific gravity could be established in both environments. Although ranking of the cultivars in both environments was not identical, both good and bad genotypes could be identified. It seems that mild selection for specific gravity and chip quality among glasshouse-grown seedlings can be exercised. If tubers of glasshouse-grown plants are too small to slice chips, Reflocheck Glucose test strips offer a satisfactory alternative to frying chips. Crip in UK  相似文献   

柱前衍生化高效液相色谱检测木糖液中葡萄糖含量   总被引：1，自引：1，他引：0  

贾鹏禹  孙蕊  李良玉  李洪飞  张桂芳  孙大庆  于伟 《黑龙江八一农垦大学学报》2012,24(3):41-44

建立了木糖母液及发酵液中葡萄糖的柱前衍生化HPLC检测方法。以l-苯基-3-甲基-5-吡唑啉酮（PMP）为柱前衍生化试剂,在ZORBAXEclipseXDB-C18色谱柱上,流动相采用95％A（醋酸盐缓冲液,O．1mol·L-1,pH=5．71）,5％B（乙腈）等比洗脱,检测波长245rim,带宽50nm。目标组分葡萄糖衍生物基线分离无干扰,葡萄糖在2．5-50．0mg·L-1。浓度范围内呈现良好的线性关系,方法检测限为0．2mg·L-1。方法样品前处理简便,灵敏度高,重现性好。  相似文献   

葡萄糖氧化酶对红姑娘酒陈酿过程中酚类物质的影响     

赵权 《湖北农业科学》2012,51(6):1225-1227,1236

以红姑娘(Physalis alkekengi L.)酒为试验材料研究葡萄糖氧化酶对红姑娘酒陈酿过程中酚类物质的影响.结果表明,葡萄糖氧化酶使酚类物质的降解速率变缓,其中鞣花酸降解速率显著低于对照,儿茶素、咖啡酸、槲皮素与对照无显著差异.  相似文献   

葡萄糖调节蛋白78研究进展     

徐世文  邵成成 《东北农业大学学报》2012,(9):1-5

葡萄糖调节蛋白78(Glucose regulated protein 78ku, GRP78)又称免疫球蛋白重链结合蛋白(Immunoglobulin heavy chain binding protein, Bip),是位于内质网上的一种重要分子伴侣,属热休克蛋白70家族的一员,GRP78分子及其DNA分子序列结构在许多生物物种中高度保守.GRP78在内质网中参与阻止内质网新生肽聚集、调节内质网钙稳态、抗内质网相关性细胞凋亡以及启动未折叠蛋白反应等.近年来发现,GRP78与多种疾病发生发展密切相关,GRP78生物学功能研究已经引起广泛关注.  相似文献   

美洲大蠊提取物对四氧嘧啶性糖尿病小鼠作用研究     

赖泳  李同翠  罗爱俊  黄永炎  杨兴彪  罗小珍 《安徽农业科学》2012,(6):3364-3365,3367

[目的]研究美洲大蠊(MZDL)提取物对四氧嘧啶性糖尿病小鼠血糖的影响。[方法]四氧嘧啶诱发糖尿病小鼠后,随机分为模型组(MC),二甲双胍组(250 mg/kg),美洲大蠊提取物低剂量(25 mg/kg)、中剂量(50 mg/kg)、高剂量(100 mg/kg)5个组,模型组给予同体积生理盐水,分别于试验第7、14、212、8天各测定小鼠空腹血糖和体重,第25～28天每天记录进食饮水量。28 d后取血测血清中一氧化氮合酶(NOS)含量。[结果]3个剂量的美洲大蠊提取物均能减缓糖尿病小鼠消瘦和多饮多食的症状。在试验中中、高剂量组糖尿病小鼠血糖降低(P<0.05)。MZDL中、高剂量组NOS含量低于MG(P<0.01)。[结论]美洲大蠊提取物对四氧嘧啶致糖尿病小鼠具有一定的保护作用,其机制可能与其降低一氧化氮合酶水平有关。  相似文献   

Repeated post-exercise administration with a mixture of leucine and glucose alters the plasma amino acid profile in Standardbred trotters     

Katarina EA Nostell  Birgitta Essén-Gustavsson  Johan T Br?jer 《Acta veterinaria Scandinavica》2012,54(1):7

Background

The branched chain amino acid leucine is a potent stimulator of insulin secretion. Used in combination with glucose it can increase the insulin response and the post exercise re-synthesis of glycogen in man. Decreased plasma amino acid concentrations have been reported after intravenous or per oral administration of leucine in man as well as after a single per oral dose in horses. In man, a negative correlation between the insulin response and the concentrations of isoleucine, valine and methionine have been shown but results from horses are lacking. This study aims to determine the effect of repeated per oral administration with a mixture of glucose and leucine on the free amino acid profile and the insulin response in horses after glycogen-depleting exercise.

Methods

In a crossover design, after a glycogen depleting exercise, twelve Standardbred trotters received either repeated oral boluses of glucose, 1 g/kg body weight (BW) at 0, 2 and 4 h with addition of leucine 0.1 g/kg BW at 0 and 4 h (GLU+LEU), or repeated boluses of water at 0, 2 and 4 h (CON). Blood samples for analysis of glucose, insulin and amino acid concentrations were collected prior to exercise and over a 6 h post-exercise period. A mixed model approach was used for the statistical analyses.

Results

Plasma leucine, isoleucine, valine, tyrosine and phenylalanine concentrations increased after exercise. Post-exercise serum glucose and plasma insulin response were significantly higher in the GLU+LEU treatment compared to the CON treatment. Plasma leucine concentrations increased after supplementation. During the post-exercise period isoleucine, valine and methionine concentrations decreased in both treatments but were significantly lower in the GLU+LEU treatment. There was no correlation between the insulin response and the response in plasma leucine, isoleucine, valine and methionine.

Conclusions

Repeated post-exercise administration with a mixture of leucine and glucose caused a marked insulin response and altered the plasma amino acid profile in horses in a similar manner as described in man. However, the decreases seen in plasma amino acids in horses seem to be related more to an effect of leucine and not to the insulin response as seen in man.  相似文献   

Fucoidan regulate blood glucose homeostasis in C57BL/KSJ m+/+db and C57BL/KSJ db/db mice     

Kim KJ  Yoon KY  Lee BY 《Fitoterapia》2012,83(6):1105-1109

Type 2 diabetes mellitus is a multisystem disease that is characterized by hyperglycemia and is associated with the dysfunction and failure of various organs. The control of postprandial hyperglycemia is important in the prevention and intervention of type 2 diabetes. Fucoidan has several biological activities in vitro and in vivo. However, the effect of fucoidan on hyperglycemia in non-diabetic and diabetic mice has not been investigated. This study was undertaken to study the effects of different molecular weight forms (5 kilodalton (k), 5-30 k and crude) of fucoidan on oral glucose tolerance tests in non-diabetic mice and on food intake, weight gain, fasting blood glucose and blood biochemistry of db/db mice. Treatment with 200 mg/mL 5 k, 5-30 k and crude fucoidan substantially prevented hyperglycemia according to oral glucose tolerance tests in non-diabetic mice. In addition, fucoidan fractions significantly reduced blood glucose levels in diabetic mice.  相似文献   

Effects of quinoa hull meal on piglet performance and intestinal epithelial physiology     

Carlson D  Fernandez JA  Poulsen HD  Nielsen B  Jacobsen SE 《Journal of animal physiology and animal nutrition》2012,96(2):198-205

Saponin-containing feed additives have shown positive effects on pig performance. Quinoa hull has high saponin content and may be of interest as a feed additive. This study aimed to evaluate quinoa hull meal (QHM) as a feed additive in a pig diet. The effects of QHM were assessed for three dosages of South American (SA) origin (100, 300 and 500 mg/kg) and one dosage of Danish (DK) quinoa (300 mg/kg). In addition, the effect of dietary SA-QHM and SA-QHM-extract on jejunal epithelial physiology was studied ex vivo in Ussing chambers. The experiment included 400 piglets weaned at 28 ± 2 days of age and the experimental period was 4 weeks. Piglets were weighed initially and finally and feed intake registered. The ex vivo studies were performed with epithelium from 40 pigs receiving control or SA-QHM. Epithelium from each pig was placed into eight Ussing chambers, where four concentrations of SA-QHM-extract were added. Epithelial permeability, Na(+)-dependent glucose transport and serotonin (5-HT) and theophylline-induced secretion were measured. The results showed that QHM had no influence on piglet's growth (p = 0.41) or feed intake (p = 0.17). In spite of a large difference in saponin content between SA-QHM and DK-QHM (28.7% and 2.0% w/w respectively) the source did not affect pig performance. The ex vivo studies revealed no effect (p > 0.05) of adding QHM-extract into the medium. The permeability and glucose induced absorption were highest (p = 0.003 and p = 0.04 respectively) in epithelium from pigs that consumed 100 or 300 mg/kg SA-QHM. The secretory response to 5-HT was not affected (p = 0.59) by dietary treatments, but the theophylline-induced secretion decreased (p = 0.02) with increasing dietary SA-QHM. The changes in epithelial physiology measured ex vivo did not affect animal performance in vivo in this study.  相似文献