两种组胺受体拮抗剂对内毒素作用下雏鸡体温的影响     

付学智  欧德渊  许乐仁  李进国  谭建民 《贵州农业科学》2007,35(5):79-81

为了研究组胺H1、H2受体拮抗剂对内毒素攻毒后雏鸡体温的影响,探讨内源性组胺在内毒素攻毒时导致雏鸡发热的作用机理。采用100羽雏鸡随机分5组,即模型组、扑尔敏组、西咪替丁组、扑和西联合组和空白组。空白组中午腹腔注射生理盐水,其余各组注射等剂量的LPS,早、晚肌注相应药物。实验持续15 d,分别于攻毒后0 d、5 d、10 d、15 d,各组随机抽10个样本。在注射LPS后0 h、2 h、4 h6、h,测定雏鸡直肠温度,结果:(1)急性实验中,扑尔敏组2 h、4 h体温显著降低(P<0.05);而西咪替丁组和扑和西联合组在2h时体温极显著降低(P<0.01)。(2)慢性实验中,0 d5、d体温无显著差异;10 d、15 d扑尔敏组体温显著降低(P<0.05);15 d扑尔敏组、扑和西联合组体温显著降低(P<0.05)。结果表明:在内毒素引起的炎症反应中,内源性组胺主要是通过H1受体介导体温升高。  相似文献   

东海秋带鱼聚集分布与水团的关系   总被引：2，自引：0，他引：2  

王建中 《水产学报》1987,11(4):339-346

带鱼Trichiurus lepturus Linnaeus是我国海洋渔业中主要的中下层经济鱼类之一,渔业生产产量居第一位。但在长期的渔业生产实践中。主要靠经验凭机会探索中心渔场。由于缺乏鱼类集群与分布规律的理论依据,渔汛预报也常常是困难的。因而,就鱼类的分布特点,聚集状态和规律进行探讨研究,在理论上和实践上都有重要意义。本文试图以统计分析的方法,对带鱼在秋汛的聚集分布类型与规律作初步的探讨,以求索科学合理和切合实际的渔场预报方法,井对一些渔业上常见的现象进行分析证明。 鱼类的集群,除水温以外.还受到其它诸如风情,盐度,潮汐等因子的制约。本文由于资料有限,仅就海洋中水温,水团分布与鱼类聚集、分布的关系进行初步分析探讨。更进一步地研究海况诸因子,找出它们与鱼类聚集之间有规律性关系,对我们的渔情预报无疑是有帮助的。  相似文献   

Formation of Biogenic Amines in Delayed Salt-Cured Whole and Gutted Indian Oil Sardines (Sardinella longiceps)     

Thamizhselvan Surya  Robinson Jeya Shakila  Narayanan Asha Hema Malini  Mani Palanikumar  Venkatesan Alamelu 《Journal Of Aquatic Food Product Technology》2018,27(3):394-404

The formation of biogenic amines in Indian oil sardines (Sardinella longiceps) collected from the Tuticorin coast of South India and treated with delayed salt-curing was investigated. Sardines were wet salt-cured in whole and gutted forms and examined in fresh and after 6, 9, 12, and 15 h delayed conditions at ambient temperature (32 ± 2°C) at four stages of salt-curing process for quality parameters and formation of biogenic amines. Moisture content decreased from 76% to 11.3% in salting followed by drying. Similarly, water activity reduced from 0.96 to 0.74 in salt-cured sardines. In contrast, total volatile base nitrogen content increased from 79 to 3,590 mg kg^–1 in salt-cured sardines. Halophilic count of sardines was higher (8 log cfu g^–1) after salting and decreased in drying stages. The 15 h delayed salt-cured whole sardines had higher histamine contents (1,568.27 mg kg^–1), cadaverine (4,059.84 mg kg^–1), putrescine (1,604.95 mg kg^–1), and tyramine (862.94 mg kg^–1) on the final day of drying. Whole sardines had higher biogenic amines and halophilic bacterial counts than the gutted sardines. The whole and gutted sardines salt-cured up to a delay of 6 and 12 h, respectively, at ambient temperature yielded the acceptable quality products with respect to biogenic amines.  相似文献   

苦参碱对断奶仔猪腹泻胃肥大细胞的影响初报     

姚红艳  刘小惠  熊凤兰  李诗举  李秀富  欧德渊 《山地农业生物学报》2011,30(4):344-347

通过在日粮中添加苦参碱,研究其对断奶仔猪腹泻及胃肥大细胞的影响,以揭示其防治断奶仔猪腹泻机理.结果表明:苦参组腹泻率(0)显著低于对照组(75％)(P＜0.05);苦参组胃贲门区( 108.7±10.1)个/cm2和胃幽门区黏膜肥大细胞数量(126.7±12.6)个/cm2极显著高于对照组(P＜0.01),苦参组胃底部...  相似文献   

Effects of a 1% hydrocortisone conditioner on haematological and biochemical parameters, adrenal function testing and cutaneous reactivity to histamine in normal and pruritic dogs     

Thomas  Logas  Radosta  & Harrison 《Veterinary dermatology》1999,10(2):109-116

The purpose of this double-blinded study was to examine the effects of a 1% hydrocortisone, leave-on conditioner on haematological and biochemical parameters, adrenal function tests, and cutaneous reaction to serial dilutions of histamine phosphate in normal dogs and those with pruritic dermatitis. Groups 1 and 2 each consisted of eight normal dogs. Seven pruritic dogs comprised Group 3. All dogs were bathed twice weekly for 6 weeks. Groups 1 and 3 had 1% hydrocortisone conditioner applied after each bath. Group 2 had vehicle from the conditioner applied after each bath. The amount of 1% hydrocortisone applied to the treated dogs ranged from 278 to 416 mg/m². Haematological and biochemical analysis and adrenocorticotrophic hormone (ACTH) stimulation tests were performed on all dogs on days 0, 14, 28, and 42. Mean values for all blood and serum parameters remained within normal limits during the study. Post-ACTH cortisol levels were significantly lower in Group 3 compared to Groups 1 and 2 on day 42 (P < 0.05) and when averaged over all days of the study (P < 0.05 and P < 0.01, respectively). Serum alkaline phosphatase levels were significantly lower in Group 3 on day 0, compared to days 14 (P < 0.05), 28 (P < 0.01), and 42 (P = 0.05). All dogs received intradermal injections of buffered saline and five serial dilutions of histamine phosphate on days 0, 14, 28, and 42. No significant differences were apparent among the groups in subjective and objective evaluation of intradermally injected dilutions of histamine. In this study, the use of a 1% hydrocortisone leave-on conditioner did not result in clinically evident adverse effects, and only minor changes in blood parameters were detected. Although mean values in all groups remained within reference ranges throughout the study, the finding of statistically significant lower post-ACTH cortisol concentrations in the pruritic dogs (Group 3) suggests that absorption of hydrocortisone may have occurred. The results of this study also show that this product does not significantly suppress cutaneous reactivity to histamine in normal and pruritic dogs.  相似文献   

The isolated,perfused bovine ear. A model for pharmacological study of cutaneous vasculature and anaphylaxis     

K. I. Eghianruwa  P. Eyre 《Veterinary research communications》1991,15(2):117-125

Bovine ears were catheterized and perfused with Krebs-Henseleit (K-H) solution at a constant flow rate. The perfusion pressure (PP) was monitored using a pressure transducer coupled to a carrier preamplifier, amplifier and a pen recorder. Dose-response curves to phenylephrine, histamine and 5-hydroxytryptamine were obtained. The ear preparations responded to these agonists dose-dependently by increases in perfusion pressure. Ear preparations from sensitized calves were challenged with 0.05 ml of horse serum which caused increased perfusion pressure. These preliminary results suggest that the perfused bovine ear represents a promising, simple, inexpensive model for the study of pharmacological mechanisms of the skin.  相似文献   

饲料组胺对美洲鳗鲡生长及肌肉品质的影响     

胡家财  马德英  陈学豪  翟少伟 《饲料研究》2019,(6):34-37

为研究饲料组胺对美洲鳗鲡生长及肌肉品质的影响,将重量[(2 870.0±17.1)kg/池)]和规格(7.8±0.3)P接近的养殖美洲鳗鲡的4口精养池,随机分为2个组,分别投喂组胺水平为67 mg/kg和414 mg/kg的试验饲料,每组2个重复,试验期为2个月。结果表明,与低组胺水平组相比,高组胺水平组美洲鳗鲡的增重率和饲料效率有降低的趋势(P<0.1);肌肉中多种多不饱和脂肪酸比例显著降低(P<0.05),氨基酸水平无显著变化(P>0.05)。综上所述,饲料中的组胺可一定程度抑制美洲鳗鲡生长和降低肌肉品质。  相似文献   

Effect of Acidification with Encapsulated Lactate on Microbiological,Textural and Sensory Properties of Cooked,Comminuted Fish Loaves     

《Journal Of Aquatic Food Product Technology》2013,22(4):55-66

A standard formulation for cooked, comminuted fish loaf was supplemented with encapsulated lactate (melting temperature =60ºC) to assess the usefulness of this additive for shelf-life extension. Slices of standard (pH= 6.45) and acidified (pH =4.86) loaf were packaged in air and under vacuum, stored at 4ºC and subjected to bacteriological analysis (total mesophilic and psychrotrophic plate counts, enumeration of Enterobacteriaceae and lactic acid bacteria) at weekly intervals. Texture profile analysis and sensory evaluation were also performed to determine the effect of acidification on the physico-chemical properties of the loaves. Use of encapsulated lactate in the formulation doubled the shelf-life from 2 to 4 weeks, due in part to strong inhibition of the Enterobacteriaceae. Texture profile analysis revealed that acidified fish loaf was softer and less rigid than the standard product. Cohesiveness scores determined by sensory evaluation confirmed this change in texture. Panelists also recorded undesirable increases in juiciness, saltiness and acidity at the level of use employed in these studies.  相似文献   

中国铠甲虾类一新种和三新纪录     

钟振如  王复振 《水产学报》1989,13(1):65-69

中国水产科学研究院南海水产研究所在1981—1982年对南海北部大陆斜坡进行调查,范围北纬18°30′—20°50′,东经112°00′—116°30′,水深250—950米,采集得不少铠甲虾,这是属于甲壳纲Crustacea歪尾次目Anomura铠甲虾总科Galatheoidea,计有六种;其中长额仿刺铠虾Munidopsis longirostris Edwards et Bouvier 1897及日本粒折尾虾Uroptychus granulatus japonicus Balss 1903东海也有已报导,本文从略。另有一新种和三新纪录,现报导如下:  相似文献   

二磷酸组织胺对奶牛血浆内毒素含量的影响   总被引：7，自引：2，他引：5  

齐长明  王清兰  钟友刚 《中国兽医杂志》2000,26(2):11-13

本文采用动物实验方法，给８头健康奶牛颈部皮下注射二磷酸组织胺，剂量为１５０μｇ／ｋｇ体重。于给药前、给药后２小时和１２小时分别采取血样，采用试验法测定血浆内毒素含量，结果表明，给药前血浆内毒素含量平均为０．３９Ｅｕ／ｍｌ，给药后２小时和１２小时分别为０．７１Ｅｕ／ｍｌ和０．８３Ｅｕ／ｍ；。与给药前相比，给药后１２小时，血浆内毒素含量极显著升高（Ｐ〈０．００５）。文章首次报道了组织胺对血浆内毒含量的  相似文献