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洛美沙星搽剂防治仔猪黄、白痢试验报告 总被引：1，自引：0，他引：1
大肠杆菌是一种条件性致病菌。应用抗生素治疗大肠杆菌病的用药途径一向是打针、灌药,但旧方法既低效又费力。本文研究透皮吸收制剂———洛美沙星搽剂对仔猪黄白痢的临床防治效果,现报告如下:1材料与方法1.1试验用药物洛美沙星透皮吸收搽剂(以下简称洛美沙星搽剂)以洛美沙星原料药(江苏常州第二制药厂生产)与氮酮(广东省助剂化工厂生产)按药剂学方法由福建农林大学研制。该搽剂每毫升含洛美沙星4毫克。本文所用的盐酸洛美沙星注射液(洛奇),为常州第二制药厂兽药分厂生产,批号:9904291。1.2参试仔猪及分组设计试验分洛美沙星搽剂预防和治疗… 相似文献
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建立了氟苯尼考注射液、柴胡注射液中非法添加培氟沙星、洛美沙星的HPLC-PDA检查方法。采用十八烷基硅烷键合硅胶为填充剂;以磷酸溶液-乙腈-甲醇(85.5∶7.0∶7.5)为流动相;二极管阵列检测器,提取波长为277 nm。通过液相色谱保留时间、峰纯度检查和光谱相似度检查对非法添加物进行确证。结果表明,该色谱条件下培氟沙星、洛美沙星与其他物质分离良好。培氟沙星在氟苯尼考注射液、柴胡注射液中的平均回收率分别为101.4%(RSD=0.2%)、100.0%(RSD=0.4%),洛美沙星在氟苯尼考注射液、柴胡注射液中的平均回收率分别为101.2%(RSD=0.1%)、99.8%(RSD=0.5%)。本方法简便、准确、可靠,可用于检查氟苯尼考注射液、柴胡注射液中非法添加的培氟沙星、洛美沙星。 相似文献
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<正>笔者以2010年11月23日在江西上饶市治疗猪病毒性腹泻164头为例,现将治疗经验总结如下。1临床症状病初个别猪体温有的偏高,有的正常,精神沉郁,采食量明显下降,排 相似文献
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[Objective] The aim of this study was to lay a foundation for obtaining effective traditional Chinese medicine preparations controlling chicken colibacillosis. [Method] With the western medicine Lomefloxacin Hydrochloride and Sodium Chloride Injection as the control, drug sensitivity tests of 15 single traditional Chinese herbs and seven self-made Chinese herbal compounds were conducted. Subsequently, the single traditional Chinese herbs presenting good in vitro antibacterial effects against Escherichia coli and all the seven compounds were given to the chicks artificially infected with E.coli to observe their efficacies. [Result] The results of drug sensitivity tests showed that all the 15 traditional Chinese herbs had certain antibacterial effect against E.coli, among which aloe, pomegranate rind and radix sanguisorbae were the best. Compound 1, 2 and 5 had good antibacterial effects in vitro. By in vivo test, traditional Chinese medicines showed superior efficacies on infected chicks than western medicine, and compound 1 and 2 performed well. [Conclusion] Traditional Chinese medicine preparations are good at controlling Chicken colibacillosis, but their bacteriostasis mechanism in vivo was different with that in vitro. 相似文献
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