Genetics of equine bleeding disorders     

Anna R. Dahlgren  Fern Tablin  Carrie J. Finno 《Equine veterinary journal》2021,53(1):30-37

Genetic bleeding disorders can have a profound impact on a horse's health and athletic career. As such, it is important to understand the mechanisms of these diseases and how they are diagnosed. These diseases include haemophilia A, von Willebrand disease, prekallikrein deficiency, Glanzmann's Thrombasthenia and Atypical Equine Thrombasthenia. Exercise-induced pulmonary haemorrhage also has a proposed genetic component. Genetic mutations have been identified for haemophilia A and Glanzmann's Thrombasthenia in the horse. Mutations are known for von Willebrand disease and prekallikrein deficiency in other species. In the absence of genetic tests, bleeding disorders are typically diagnosed by measuring platelet function, von Willebrand factor, and other coagulation protein levels and activities. For autosomal recessive diseases, genetic testing can prevent the breeding of two carriers.  相似文献   

Mesh-like vascular changes in copper deficiency-induced rat cardiomyopathy     

Rina Yamane  Makoto Tanaka  Nao Kikugawa  Hideki Yasui  Kenta Takei  Miwa Harada  Shinya Kaneda 《Journal of toxicologic pathology》2021,34(1):127

The pathological effects of copper deficiency (COD) are well known. However, the pathogenesis of cardiomyopathy resulting from COD remains unclear. In this study, aimed to elucidate the pathogenesis of COD-induced cardiomyopathy by examining the morphology of the cardiovascular system in copper-deficient rats using histopathology, immunohistochemistry, and scanning and transmission electron microscopy. Changes detected in the myocardium and interstitium were consistent with those reported for COD. Morphological changes included mesh-like changes in the capillary endothelial cells that appear to be a novel finding in COD-induced cardiomyopathy. These changes are hypothesized to result from abnormal vascular remodeling following damage to the basement membrane and due to the mechanical effects of myocardial contractions. Although cardiomyopathy may be associated with microcirculatory disorders arising from these lesions, further investigations are necessary to demonstrate a causal relationship between the pathogenesis of cardiomyopathy and the contribution of these lesions to disease progression.  相似文献   

Relationship between a plant-based ‘vegan’ pet food and clinical manifestation of multiple nutrient deficiencies in two cats     

Marco Fantinati  Romane Dufayet  Petra Rouch-Buck  Nathalie Priymenko 《Journal of animal physiology and animal nutrition》2021,105(6):1179-1191

A topical subject in human nutrition is the steadily growing number of people choosing to limit or completely avoid all animal-derived food products either for moral dilemma, health concerns or both. To meet people's will of applying their dietary choices to their domestic animals, the pet food industry answered by launching on the market some plant-based diets. This leads to concerns about whether these diets are adequately formulated to satisfy the target species nutritional requirements, especially for cats which are still considered strict carnivores. This case report follows a 2-year-old male neutered Main Coon and a 1-year-old female spayed Domestic Shorthair cat, presented to the nutrition service of the University of Toulouse, France. Reason for consultation was lethargy with in anamnesis a recent dietary transition to a plant-based pet food. Dysorexia, lethargy and muscle waste were present at first consultation. Progressive weight loss developed during follow-ups. A macrocytic, non-regenerative anaemia with serum folates below reference were the main clinical features. Analysis of pet food showed multiple nutrients below minimum recommendation at the average daily intake of both cats. Folic acid supplementation improved dysorexia, and subsequent reintroduction of animal-derived ingredients in the diet restored appetite, weight and a normal mentation in both cases.  相似文献   

Randomized comparison of in vivo performance of TearLab® and I-PEN® osmometry in normal dogs     

Hyun-wook Kim  Joon-Young Kim 《Veterinary ophthalmology》2023,26(5):440-445

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Sharing-value and Unicity of Meromorphic Functions     

FU De-gang  SHANG Hai-tao  WU Chun 《保鲜与加工》2007,(3):83

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计算机视觉描述缺素番茄叶片颜色变化的研究   总被引：4，自引：0，他引：4  

吴雪梅  毛罕平 《农机化研究》2004,(5):212-214

利用计算机视觉系统代替人眼对番茄缺素进行自动识别的方法，通过对缺素番茄叶片彩色图像的分析研究，利用图像处理技术中的颜色分析方法，分析缺N和正常叶片的特征量随着缺素时间的变化规律．提出用G体均值、H色调均值来定量描述缺N叶片随时间的变化。结果表明：利用计算机视觉能定量描述缺N叶片颜色随缺素时间的变化。  相似文献   

对缺硼反应不同的油菜基因型根系吸收硼特性的研究   总被引：5，自引：0，他引：5  

曹享云  刘武定 《华中农业大学学报》1997,16(5):335-339

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桂林市沙糖橘叶片的营养元素丰缺状况研究     

范七君  陈传武  牛英  唐艳  刘冰浩  付慧敏  刘升球  蒋运宁  李贤良  邓崇岭  曹丽玲  莫元妹 《中国果业信息》2020,49(5)

为了解桂林市沙糖橘产区的叶片营养元素的丰缺状况,并为桂林市沙糖橘的合理施肥提供一定的理论依据,于2017年调查分析了桂林市沙糖橘产区6个县60个果园叶片的氮(N)、磷(P)、钾(K)、钙(Ca)、镁(Mg)、硼(B)、铁(Fe)、锰(Mn)、铜(Cu)、锌(Zn)的含量状况。结果显示,桂林市沙糖橘叶片中N、P、K、Ca、Mg、B、Fe、Mn、Cu、Zn的平均含量分别为：(29.92±0.36)、(1.23±0.01)、(14.54±0.78)、(32.96±1.03)、(2.67±0.10) g.kg-1和(95.77±4.72)、(50.64±8.57)、(77.42±5.70)、(4.70±0.59)、(15.72±0.95)mg.kg-1.。其中,N和B含量普遍偏多,位于高量和过量水平的果园比例分别为43.33%和78.33%;P、K、Ca、Mg、Cu和Zn的含量普遍存在偏少现象,位于低量和缺乏水平的果园比例分别为38.33%、35.00%、40.00%、43.33%、65.00%和81.67%;Fe和Mn的含量适中的果园比例分别为65%和66.67%,均同时存在偏多或偏少的现象。桂林市沙糖橘产区树体营养元素失衡现象普遍存在,生产上应减少N和B肥的用量,重视补充P、K、Ca、Mg、Cu、Zn肥,合理施用Fe和Mn肥,以确保树体营养均衡,实现沙糖橘的优质丰产。  相似文献   

GM1 gangliosidosis in a Japanese domestic cat: a new variant identified in Hokkaido,Japan     

Hiroshi UENO  Osamu YAMATO  Takeshi SUGIURA  Moeko KOHYAMA  Akira YABUKI  Kenjiro MIYOSHI  Kazuya MATSUDA  Tsuyoshi UCHIDE 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2016,78(1):91-95

A male Japanese domestic cat with retarded growth in Hokkaido, Japan, showed progressive motor dysfunction, such as ataxia starting at 3 months of age and tremors, visual disorder and seizure after 4 months of age. Finally, the cat died of neurological deterioration at 9 months of age. Approximately half of the peripheral blood lymphocytes had multiple abnormal vacuoles. Magnetic resonance imaging showed bisymmetrical hyperintensity in the white matter of the parietal and occipital lobes in the forebrain on T2-weighted and fluid-attenuated inversion recovery images, and mild encephalatrophy of the olfactory bulbs and temporal lobes. The activity of lysosomal acid β-galactosidase in leukocytes was negligible, resulting in the biochemical diagnosis of GM1 gangliosidosis. Histologically, swollen neurons characterized by accumulation of pale, slightly granular cytoplasmic materials were observed throughout the central nervous system. Dysmyelination or demyelination and gemistocytic astrocytosis were observed in the white matter. Ultrastructually, membranous cytoplasmic bodies were detected in the lysosomes of neurons. However, genetic analysis did not identify the c.1448G>C mutation, which is the single known mutation of feline GM1 gangliosidosis, suggesting that the cat was affected with a new variant of the feline disease.  相似文献   

南方早熟砂梨缺镁黄叶症诊断与矫治     

黄若展 《中国果业信息》2014,43(4)

通过对福建省德化县早熟砂梨“黄叶病株”及“正常植株”叶片及土壤的营养诊断分析：黄叶病株叶片平均含镁量0.131%,极显著低于正常植株0.328%;黄叶症较重的果园土壤交换态镁含量低12.6～24.5㎎/㎏及土壤酸性强pH3.6～4.5,诊断结论砂梨叶片黄化现象为镁素缺乏所致。矫治试验效果,叶面喷施1%硝酸镁3次,可以叶色转绿;12月份土壤基施钙镁磷肥株1.3 kg,翌年5月份后有明显矫治效果。  相似文献