伏龙肝药学研究概况     

巩江  骆蓉芳  高昂  沈秋红  侯恩太  赵婷  路锋  倪士峰  孙芳云 《安徽农业科学》2010,38(35):20496-20496,20498

综述了伏龙肝的化学成分、药理、临床应用,为其深入开发利用提供了参考。  相似文献   

资源植物杜香的研究进展     

马雪梅 《安徽农业科学》2010,38(6):2949-2950

介绍了杜香的化学成分,综述了其在药理、临床、保健营养及栽培等方面的研究进展,并对杜香未来的研究方向进行了展望。  相似文献   

赤爮属药用研究概况     

陈星宇  巩江  倪士峰  路锋  侯恩太  李文华  孙芳云 《安徽农业科学》2010,38(17):9363-9364

在广泛文献检索的基础上,对赤爮属植物的产地、品种、成分、药理作用和临床应用等方面进行了综述,为更进一步的研究赤爮属植物的药用价值提供资料依据。  相似文献   

磁石的药用研究概况     

吴锦斌  巩江  倪士峰  仝瑛  骆蓉芳  侯恩太  田苗 《安徽农业科学》2010,38(17):9375-9376

对磁石成分、工艺、药理及临床应用进行了概述,为深入开发利用提供参考依据。  相似文献   

Cytokine profiles, apoptosis and pathology of experimental Pasteurella multocida serotype A1 infection in mice     

P. Ezhil Praveena  Sivakumar Periasamy  A.A. Kumar  Nem Singh 《Research in veterinary science》2010,89(3):332-339

Mice were experimentally infected with Pasteurella multocida serotype A1 to study the cytokine profiles, host cell apoptosis and sequential pathology at different hours of post-infection. Infected mice were dull, anorectic and depressed. A transient leukocytopenia followed by progressive leukocytosis was observed in the course of infection. Serum cytokine profiles showed significantly (P < 0.01) higher amount of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6 and mouse KC) in the infected mice when compared to control mice. The circulating lymphocytes were apoptotic on annexin V staining. Apoptotic nuclei were detected in splenocytes, hepatocytes and infiltrating leukocytes of the lungs on TUNEL staining. The lungs were grossly congested and hemorrhagic, and showed infiltration with polymorphonuclear cells at early and mononuclear cells in the late hours of infection. Alveolar epithelia, inter-alveolar septa and capillary endothelium of the lungs showed ultrastructural changes. Liver had degenerative changes in histological and ultrathin sections.  相似文献   

八角枫药学研究概况     

吴一飞  巩江  赵婷  范文娟  范存刚  李鑫  倪士峰 《安徽农业科学》2010,38(20):10676-10677

在广泛调研文献基础上,概述了中药八角枫的资源、成分、药理及临床应用,为深入开发利用提供基础资料。  相似文献   

Comparison of chemistry analytes between 2 portable, commercially available analyzers and a conventional laboratory analyzer in reptiles     

McCain SL  Flatland B  Schumacher JP  Clarke Iii EO  Fry MM 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2010,39(4):474-479

Background: Advantages of handheld and small bench‐top biochemical analyzers include requirements for smaller sample volume and practicality for use in the field or in practices, but little has been published on the performance of these instruments compared with standard reference methods in analysis of reptilian blood. Objective: The aim of this study was to compare reptilian blood biochemical values obtained using the Abaxis VetScan Classic bench‐top analyzer and a Heska i‐STAT handheld analyzer with values obtained using a Roche Hitachi 911 chemical analyzer. Methods: Reptiles, including 14 bearded dragons (Pogona vitticeps), 4 blue‐tongued skinks (Tiliqua gigas), 8 Burmese star tortoises (Geochelone platynota), 10 Indian star tortoises (Geochelone elegans), 5 red‐tailed boas (Boa constrictor), and 5 Northern pine snakes (Pituophis melanoleucus melanoleucus), were manually restrained, and a single blood sample was obtained and divided for analysis. Results for concentrations of albumin, bile acids, calcium, glucose, phosphates, potassium, sodium, total protein, and uric acid and activities of aspartate aminotransferase and creatine kinase obtained from the VetScan Classic and Hitachi 911 were compared. Results for concentrations of chloride, glucose, potassium, and sodium obtained from the i‐STAT and Hitachi 911 were compared. Results: Compared with results from the Hitachi 911, those from the VetScan Classic and i‐STAT had variable correlations, and constant or proportional bias was found for many analytes. Bile acid data could not be evaluated because results for 44 of 45 samples fell below the lower linearity limit of the VetScan Classic. Conclusions: Although the 2 portable instruments might provide measurements with clinical utility, there were significant differences compared with the reference analyzer, and development of analyzer‐specific reference intervals is recommended.  相似文献   

A Pressure Algometer Is a Useful Tool to Objectively Monitor the Effect of Diagnostic Palpation by a Physiotherapist in Warmblood Horses     

Phebe De Heus  Gerry Van Oossanen  Machteld C. Van Dierendonck  Willem Back 《Journal of Equine Veterinary Science》2010

There is a lack of scientific evidence for objective evaluation of neck and back musculoskeletal sensitivity in horses, although pressure algometry has been described as an objective tool to quantify musculoskeletal responses by mechanical nociceptive threshold (MNT) values. This study aimed to evaluate the use of pressure algometry for objectively quantifying the effect of diagnostic palpation applied by physiotherapists on the musculoskeletal function of the equine neck and back. The inter-examiner repeatability of animal physiotherapists was tested, and their subjective clinical scores for the vertebral column area were objectively compared with MNT values measured at the same locations to investigate the potential clinical implementation of the pressure algometer in daily equine rehabilitation practice. Six adult Dutch Warmblood riding school mares were randomly assigned to an experimental or a control group. The MNT of all horses was measured on 35 predefined sites on the vertebral column in the morning and in the evening of the same day. In the experimental group (n = 3), neck and back surface “temperature”, “pain”, “muscle tone”, and passive “mobility” were scored through palpation by three certified physiotherapists and related to MNT measurements at the same vertebral column locations. Agreement between the physiotherapists was determined from Spearman's rank correlation coefficients (P < .05). These correlation coefficients showed a significant agreement between the scores of individual physiotherapists and with objective MNT measurements. The three physiotherapists agreed best in their subjective gradings of “pain”, but less for “temperature” and “muscle tone”, and least for “mobility”. There was also a significant difference in MNT between individual horses. The physiotherapeutic diagnostic intervention did not significantly alter the MNT of the experimental group compared with the control group. There was a significant difference, however, between morning (7.4 kg/cm²) and evening (6.9 kg/cm²) MNT-measurements within the combined group (n = 6, P < .05). In conclusion, a pressure algometer proved to be a useful tool to objectively monitor the palpation of individual Warmbloods by individual physiotherapists. The correlation of their scores to the objective MNT measurements elucidated that there were differences on which scale (“pain”, “temperature”, “muscle tone”, “mobility”) they merely relied upon in their palpation. Significant effects of physiotherapeutic diagnostic palpation on MNT, however, were not found. The lower MNT of the horses at the second trial in the evening could be a sensitization of the measurement location because of bruising, a learning effect of the horses, or a diurnal fluctuation. The use of pressure algometry has both a potential to quantify clinical neck and back musculoskeletal sensitivity in horses possibly leading to dysfunction, as well as to objectively evaluate treatment results. Repeated measurements on the same day and on the same location along the vertebral column may influence absolute MNT values. The algometer can be used with success provided that the operator has proper and frequent training.  相似文献   

Intermittent and Continuous Enteral Nutrition in Critically Ill Dogs: A Prospective Randomized Trial     

M. Holahan  S. Abood  J. Hauptman  C. Koenigsknecht  A. Brown 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2010,24(3):520-526

Background: Malnutrition is a common problem in critically ill dogs and is associated with increased morbidity and mortality in human medicine. Enteral nutrition (EN) delivery methods have been evaluated in humans to determine which is most effective in achieving caloric goals. Objectives: To compare continuous infusion and intermittent bolus feeding of EN in dogs admitted to a critical care unit. Animals: Fifty‐four dogs admitted to the critical care unit and requiring nutritional support with a nasoenteric feeding tube. Methods: Prospective randomized clinical trial. Dogs were randomized to receive either continuous infusion (Group C) or intermittent bolus feeding (Group I) of liquid EN. The percentage of prescribed nutrition delivered (PPND) was calculated every 24 hours. Frequencies of gastrointestinal (GI), mechanical, and technical complications were recorded and gastric residual volumes (GRVs) were measured. Results: PPND was significantly lower in Group C (98.4%) than Group I (100%). There was no significant difference in GI or mechanical complications, although Group C had a significantly higher rate of technical complications. GRVs did not differ significantly between Group C (3.1 mL/kg) and Group I (6.3 mL/kg) and were not correlated with the incidence of vomiting or regurgitation. Conclusions and Clinical Importance: There was a statistically significant difference in the PPND between continuously and intermittently fed dogs, but this difference is unlikely to be clinically relevant. Critically ill dogs can be successfully supported with either continuous infusion or intermittent bolus feeding of EN with few complications. Increased GRVs may not warrant termination of enteral feeding.  相似文献   

Renal tubular acidosis associated with zonisamide therapy in a dog     

Cook AK  Allen AK  Espinosa D  Barr J 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2011,25(6):1454-1457

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