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71.
A 12‐year‐old Peruvian Paso stallion was examined for scrotal swelling and unilateral testicular enlargement of 4–6 weeks duration. Physical examination and ultrasonography of the scrotum revealed an enlarged, nonpainful right testis with a well encapsulated mass at the cranial‐medial aspect containing echodense flocculent material. Unilateral castration was performed and the testis, spermatic cord and vaginal tunic were submitted for histological examination, which revealed a mastocytoma with accompanying evidence of malignancy. Short‐term follow‐up examination did not reveal any evidence of abdominal metastasis and the stallion has since successfully achieved pregnancy in a small number of mares. Although considered rare, mast cell neoplasia should be considered as a differential diagnosis when unilateral testicular enlargement is encountered.  相似文献   
72.
Scrotal enlargement is a problem in stallions that often leads to poor semen quality. Although there are many causes for scrotal enlargement, testicular neoplasia is often high on the differential list, especially in an aged stallion. This case report describes a stallion with scrotal enlargement caused by a rare neoplasia located in the tunica vaginalis, and not in the testicular parenchyma. Diagnosis of mesothelioma was made following hemicastration. Prognosis in other species is variable, but this stallion returned to his successful breeding career following treatment and has remained healthy one year following the diagnosis.  相似文献   
73.
OBJECTIVE: To examine the effect of partial arytenoidectomy without mucosal closure on postoperative racing performance and long-term complications in Thoroughbred racehorses treated for laryngeal hemiplegia, arytenoid chondropathy, or failed laryngoplasty. STUDY DESIGN: Retrospective study. ANIMALS: Twenty-seven Thoroughbred racehorses. METHODS: Medical records of Thoroughbred racehorses that had partial arytenoidectomy without mucosal closure between 1992 and 2002 were reviewed. Horses were divided into groups: horses that had not raced (Group 1) and those that had raced (Group 2) before surgery. Lifetime race records were compared between groups. A standard starts index (SSI) and performance index (PI) were used for Groups 1 and 2, respectively, to objectively evaluate each horse's postoperative performance. Telephone interviews of owners and trainers were used for subjective performance evaluation and to determine prevalence of long-term complications. RESULTS: Eleven (61%) Group 1 and 7 (78%) Group 2 horses raced and earned money after surgery. All Group 1 horses that raced performed at a level lower than the national average. Only 1 Group 2 horse had an improved PI score postoperatively. CONCLUSIONS: Thoroughbred racehorses have a fair prognosis for racing successfully after partial arytenoidectomy without mucosal closure. CLINICAL RELEVANCE: This technique may be a practical alternative to primary mucosal closure, would decrease surgical time, and avoid some problems reported with primary mucosal closure.  相似文献   
74.
In 2020, an outbreak of equine coronavirus (ECoV) infection occurred among 41 horses at a riding stable in Tokyo, Japan. This stable had 16 Thoroughbreds and 25 horses of other breeds, including Andalusians, ponies and miniature horses. Fifteen horses (37 %) showed mild clinical signs such as fever, lethargy, anorexia and diarrhoea, and they recovered within 3 days of onset. A virus neutralization test showed that all 41 horses were infected with ECoV, signifying that 26 horses (63 %) were subclinical. The results suggest that subclinical horses played an important role as spreaders. A genome sequence analysis revealed that the lengths from genes p4.7 to p12.7 or NS2 in ECoV differed from those of ECoVs detected previously, suggesting that this outbreak was caused by a virus different from those that caused previous outbreaks among draughthorses in Japan. Among 30 horses that tested positive by real-time RT-PCR, ECoV shedding periods of non-Thoroughbreds were significantly longer than those of Thoroughbreds. The difference in shedding periods may indicate that some breeds excrete ECoV longer than other breeds and can contribute to the spread of ECoV.  相似文献   
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Reasons for performing the study: Hoof health is a major concern of horse owners as well as the equine industry. However, many questions remain concerning regional variations of laminar junction and its potential to remodel. Hypothesis: To examine regional variations in the morphology of the laminar junction and thickness of the hoof wall in Thoroughbred horses. Methods: The forefeet of 25 Thoroughbred cadavers were examined. Each hoof was divided into 20 blocks through 4 proximodistal slices (below the coronary band, each 1 cm apart) and 5 circumferential positions (toe, medial and lateral quarters and heels). In each block, 25 central primary epidermal laminae (PEL) were considered. Orientation of each lamina in relation to the hoof wall (LO), degree of bending (IA) and the spaces between the adjacent laminae (LS) were measured. Thickness of the hoof wall and number of branched PEL were also measured. Data were analysed using a split‐block design in ANOVA. Results: There were significant differences between the 2 proximal and 2 distal slices in LO and IA data, but not in LS data. Circumferentially, toe blocks were different from heel and quarters blocks. Lateral and medial heels as well as the quarters were mostly different. The hoof wall was slightly thicker laterally than medially. There were more branched PEL on the lateral side of the left hooves and on the medial side of the right hooves. Conclusions: These data add to the circumstantial evidence supporting the hypothesis of adaptive remodelling in the laminar junction. Results of this study signify the capability of PEL to remodel in response to applied stress to the regions of the hoof. Potential relevance: A deeper understanding of the gross and cellular processes of laminar remodelling may well prove to be complementary to an understanding of their failure in laminitis.  相似文献   
78.
The objective of this study was to investigate the prevalence, severity and risk factors associated with oesophageal and nonglandular gastric lesions in Thoroughbred racehorses in active training in Saskatoon. Mature Thoroughbred horses (n = 94), stabled at Marquis Downs racetrack in Saskatoon, Saskatchewan, Canada, and trained by different trainers (n = 14) for a minimum of one month were included in the study. Horses were examined by gastroscopy and a lesion grade was assigned for each individual horse. Of the 94 horses, 79 (84%) had nonglandular gastric lesions, 70 (74.5%) had gastric ulcers, giving a prevalence of 74.5%, and 9 out of 94 horses (9.6%) had hyperkeratosis and/or hyperaemia. None of the horses had oesophageal lesions. Gender, age, number of races raced, place obtained in those races, history of lameness, history of medical conditions, and history of medications in a 2 month period prior to the gastroscopic examination were not statistically significant as potential risk factors for the prevalence and severity of nonglandular gastric lesions.  相似文献   
79.
The effects of three vehicles, phosphate-buffered saline (PBS), ethanol (50% in PBS w/w) and propylene glycol (50% in PBS w/w) on in vitro transdermal penetration of testosterone was investigated in the horse. Skin was harvested from the thorax of five Thoroughbred horses after euthanasia and stored at −20°C until required. The skin was then defrosted and placed into Franz-type diffusion cells, which were maintained at approximately 32°C by a water bath. Saturated solutions of testosterone, containing trace amounts of radiolabelled [14C]testosterone, in each vehicle were applied to the outer (stratum corneum) surface of each skin sample and aliquots of receptor fluid were collected at 0, 2, 4, 8, 16, 20, 22 and 24 h and analysed for testosterone by scintillation counting. The maximum flux (J max) of testosterone was significantly higher for all sites when testosterone was dissolved in a vehicle containing 50% ethanol or 50% propylene glycol, compared to PBS. In contrast, higher residues of testosterone were found remaining within the skin when PBS was used as a vehicle. This study shows that variability in clinical response to testosterone could be expected with formulation design.  相似文献   
80.
The training programme for Thoroughbred flat racehorses is intense, with pressure to limit nontraining days. Fracture of the dorsal spinous processes is a traumatic event that affects a horse's ability to train and race, with little information available regarding short‐term treatment and long‐term outcomes for elite racing horses. Using a retrospective cohort study of the Hong Kong Jockey Club's veterinary clinical records, cases of wither fracture were identified radiographically, with clinical features, treatment and subsequent return to training and racing described. The prevalence of wither fracture was 0.152% and in 6 out of 8 cases, the fracture occurred following identified trauma. Clinical signs varied from mild swelling and pain of the affected region to acute, severe forelimb lameness with spinal deformation. Prognosis for recovery was excellent, with all horses returning to a level of racing performance equal to or better than before the injury. The time from injury to return to ridden work was <2.5 months and return to racing was 9 months, with horses that returned to training sooner after injury having more favourable outcomes. The period of rest identified in this study was shorter than previously reported, with the median interval between injury and first gallop <2.5 months and most horses back racing within 6 months.  相似文献   
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