Anthelmintic Resistance on an Organized Sheep Farm in India     

Swarnkar CP  Sanyal PK  Singh D  Khan FA  Bhagwan PS 《Tropical animal health and production》2001,33(4):305-312

Monitoring anthelmintic resistance in strongyle nematodes by the faecal egg count reduction test and a commercial larval development assay on an organized sheep farm in the semi-arid area of Rajasthan revealed the emergence of resistance to benzimidazoles and rafoxanide and a potential risk of the development of levamisole/tetramisole resistance. A benzimidazole/levamisole combination, avermectins and closantel were each found to be efficacious.  相似文献   

A questionnaire study of equine gastrointestinal parasite control in Scotland     

C. H. Stratford  H. E. Lester  E. R. Morgan  K. J. Pickles  V. Relf  J. B. Matthews 《Equine veterinary journal》2014,46(1):25-31

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A combination treatment strategy using pyrantel pamoate and oxibendazole demonstrates additive effects for controlling equine cyathostomins     

R. M. Kaplan  E. M. West  L. M. Norat‐Collazo  J. Vargas 《Equine Veterinary Education》2014,26(9):485-491

Anthelmintics of the avermectin/milbemycin class continue to demonstrate the highest efficacy against cyathostomin nematodes; however, over‐reliance on these drugs is increasing the likelihood that recent emerging resistance to these drugs will worsen. Use of benzimidazole and pyrantel compounds given concurrently may provide sufficiently high efficacy to serve as a viable treatment alternative to the avermectin/milbemycin drugs, thus reducing the selective pressures for resistance development. The study was conducted to determine if oxibendazole (OBZ) and pyrantel pamoate (PYR) would have greater efficacy when used in combination vs. what either drug could achieve individually, and to determine if the combination protocol would consistently achieve faecal egg count reduction (FECR) rates >90%, the general threshold for acceptable efficacy. Horses of various ages and breeds on 11 horse farms were assigned randomly to treatment with OBZ (n = 34), PYR (n = 35), or a combination of both (n = 61). A faecal egg count was performed for each horse prior to treatment and 9–14 days post treatment. Mean FECR percentages were calculated for each treatment group on individual farms, and for each treatment group across all farms. Combination treatment achieved >90% mean FECR on all 11 farms, and >95% on 9 of the 11 farms. Overall arithmetic mean FECR rates were 90.03%, 81.10% and 96.35% for horses treated respectively with OBZ, PYR, and the 2 drugs in combination. Combination treatment with OBZ and PYR demonstrated an additive effect whereby horses given both anthelmintics concurrently had mean FECR percentages that were significantly greater than in horses given either drug alone. Combination treatment with OBZ and PYR can be an efficacious and viable treatment choice for controlling cyathostomins, thereby reducing the over‐reliance on avermectin/milbemycin drugs.  相似文献   

吡丙醚用于宠物体外寄生虫防控的研究概况     

梁方印  尹相吉 《畜牧与饲料科学》2022,43(1):109-114

随着人类和宠物关系的日益密切,宠物体外寄生虫感染导致宠物瘙痒难安等问题逐渐显现,引起了人们对宠物健康的高度关注,同时,人们更应重视跳蚤、蜱等携带的病原体从宠物向人类传播的风险。为了有效预防和治疗宠物体外寄生虫病,国内外诸多研究者开发杀灭宠物体外寄生虫制剂,其中,杀虫剂吡丙醚属烷氧吡啶类保幼激素类的几丁质合成抑制剂,作用机理独特,对害虫综合治理效果显著。综述了吡丙醚的理化性质、作用机制、检测方法、抗体外寄生虫研究概况等研究进展,旨在为今后驱虫药的开发以及体外寄生虫病防控提供参考。  相似文献   

国产伊维菌素对宁夏滩羊的驱虫效力试验   总被引：3，自引：0，他引：3  

刘维华  韩博 《中国兽药杂志》1998,32(1):18-21

以国产伊维菌素对宁夏山羊的寄生线虫进行驱虫试验，在口服０．１ｍｇ／ｋｇ、０．２ｍｇ／ｋｇ和０．３ｍｇ／ｋｇｄｅ剂量后第１１天时分别获得了粪便虫卵下降９７．２％、９８．３％和９９．４％以及虫卵转阴率８０％、９５％和９５％的效果。０．３ｍｇ／ｋｇ剂量组中未找到肠道中常见的８种寄生线虫的虫体。在全部试验中，国产Ｉｖｅｒｍｅｃｔｉｎ的效力都高于进口的Ｉｖｏｍｅｃ。  相似文献   

补喂鞣花酸对哺乳期马驹寄生虫感染情况的影响     

郭翠洁  臧长江  黄新新  李佳豪  贺林娇  杨帆  任斐儿  陈开旭 《中国畜牧兽医》2022,49(12):4936-4944

【目的】研究补喂鞣花酸对哺乳期纯血马马驹肠道寄生虫感染情况的影响，揭示鞣花酸在马属动物消化道寄生虫防治方面的作用，为新型驱虫药物的筛选提供参考依据。【方法】选择平均体重（143.33±16.10） kg、出生日期（±5 d）、寄生虫感染率相近的哺乳期纯血马马驹15匹，随机分为对照组、试验Ⅰ和Ⅱ组，每组5匹。在相同的饲养条件下，对照组马驹不做任何处理，试验Ⅰ组马驹每天补喂15 mg/kg BW鞣花酸，试验Ⅱ组补喂30 mg/kg BW鞣花酸，试验期60 d，分别在试验的第0、15、30、45、60天采集马驹粪便样品，检测各组虫卵种类，统计虫卵数量，并评价驱虫效果。【结果】哺乳纯血马驹感染率高的寄生虫有10种，其中感染率最高的寄生虫是马副蛔虫、马圆线虫及细颈三齿线虫。随着鞣花酸补喂时间的延长及剂量的增加，寄生虫的感染率呈降低趋势，细颈三齿线虫卵、马圆线虫卵、马副蛔虫卵和韦氏类圆线虫卵的排出量显著降低（P<0.05）。补喂鞣花酸后第60天试验Ⅰ和Ⅱ组虫卵总数比对照组分别降低66.59%和97.06%；试验Ⅰ组第30和60天虫卵减少率分别为30.10%和42.97%；试验Ⅱ组第30和60天虫卵减少率分别为37.51%和49.86%。【结论】在本试验条件下，给哺乳马驹补喂鞣花酸能够显著降低寄生虫的感染及粪便中细颈三齿线虫卵、马圆线虫卵、马副蛔虫卵和韦氏类圆线虫卵的排出量，且补喂剂量为30 mg/kg BW效果更佳。  相似文献