Correlation between corneal sensitivity and quantity of reflex tearing in cows,horses, goats,sheep, dogs,cats, rabbits,and guinea pigs     

Barbara Wieser  Alexander Tichy  Barbara Nell 《Veterinary ophthalmology》2013,16(4):251-262

Objective Guinea pigs have a very low threshold of corneal sensitivity and at the same time nearly no reflex tearing compared to dogs, cats, and horses. The question arose whether there is a general correlation between corneal sensitivity and the quantity of reflex tearing. Animals studied Totally 160 animals of 8 different species (20 animals per species) were investigated. Procedures The corneal touch threshold (CTT) was measured with a Cochet–Bonnet esthesiometer. The palpebral fissure length (PFL) was measured with a calliper ruler. The Schirmer tear test (STT) was modified by adapting the width of the STT strip to the PFL of every species. For the STT II, 0.4% oxybuprocaine was applied. Results Corneal touch threshold: Cows (1.67 g/mm²), horses (1.23 g/mm²), sheep (1.13 g/mm²), goats (1.44 g/mm²), dogs (2.16 g/mm²), and cats (1.33 g/mm²) show similar CTT values. In contrast, rabbits (6.21 g/mm²) and guinea pigs (7.75 g/mm²) show a significantly lower CTT. Tear Production Difference STT I ? STT II: Rabbits have the greatest decline in tear production with 38.4%, followed by sheep (33.3%), dogs (31.1%), cats (24.7%), cows (23.7%), horses (18.0%), and goats (14.0%). Guinea pigs have no decline, but a slight increase of ?16.0%. Correlation CTT and STT II ? STT I Difference: Pearson’s correlation coefficient shows a small, but significant correlation. The coefficient of determination can only forecast a value with 7.1% certainty. Conclusions The high variance and low reproducibility of results suggest that the measuring devices are inappropriate to assess the evaluated parameters. Therefore, no assured correlation between the corneal sensitivity and the quantity of reflex tearing could be found.  相似文献   

Relationship between corneal sensitivity,corneal thickness,corneal diameter,and intraocular pressure in normal cats and cats with congenital glaucoma     

Mary R. Telle  Nickolas Chen  Daniel Shinsako  Julie A. Kiland  Kazuya Oikawa  Ralph Mller Trane  Gillian J. McLellan 《Veterinary ophthalmology》2019,22(1):4-12

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Phenotype of macular corneal dystrophy in Labrador Retrievers: A multicenter study     

Claudia Busse  Christiane Kafarnik  Rose Linn‐Pearl  Christelle Volmer  Kaspar Matiasek  Johana E. Premont  Thomas Dulaurent  Jean‐Yves Douet  Ida Gilbert  Sari Jalomäki  Katrin Trost  Pierre‐Francois Isard  Ryan Boyd  Isabelle Raymond 《Veterinary ophthalmology》2019,22(3):294-304

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Isolation and cultivation of canine corneal cells for in vitro studies on the anti-inflammatory effects of dexamethasone   总被引：3，自引：2，他引：1  

Werner A  Braun M  Kietzmann M 《Veterinary ophthalmology》2008,11(2):67-74

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Corneal abrasion and microbial contamination in horses following general anaesthesia for non-ocular surgery     

Stefania Scarabelli  Dorina Timofte  Fernando Malalana  David Bardell 《Veterinary anaesthesia and analgesia》2018,45(3):278-284

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Keratometry in normal cats: a cross-sectional study in Japan using an automated handheld keratometer     

Minae KAWASAKI  Tomoya FURUJO  Kazuo AZUMA  Yoshiharu OKAMOTO  Norihiko ITO 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(8):1256

Keratometry was performed in 73 domestic cats of varied signalment in Japan using an automated handheld keratometer. The mean corneal curvature radius was significantly lower for cats younger than 1 year than for those older than 2 years (8.04 mm vs. 8.80−8.99 mm, P<0.01). The radius was significantly greater in males than in females among the cats older than 11 years (9.22 mm vs. 8.84 mm, P=0.01), while the age distributions of the males and females were similar. Corneal astigmatism did not significantly differ across the gender and age groups. The predictability of the corneal curvature and astigmatism was approximately 41−43% and less than 3%, respectively, as a function of age and bodyweight. The results highlighted some age- and sex-related keratometric variations in domestic cats in Japan.  相似文献   

Primary bilateral corneal nerve sheath neoplasm in a dog          下载免费PDF全文

Marina L. Leis  M. Elyse Salpeter  Bianca S. Bauer  Dale L. Godson  Bruce H. Grahn 《Veterinary ophthalmology》2017,20(4):365-371

A 15‐year‐old, neutered male, Shih Tzu cross developed progressive corneal stromal thickening and vascularization of the right eye, and 5 months later, of the left eye. Both eyes became blind due to extensive corneal opacification and were enucleated. Light microscopic examination revealed a diffuse corneal infiltrate of neoplastic mesenchymal cells, and immunohistochemistry revealed diffuse cytoplasmic vimentin immunoreactivity and variable cytoplasmic and nuclear immunoreactivity for S100 in the neoplastic cells. Transmission electron microscopy revealed desmosomes between contiguous cells, thread‐like cytoplasmic processes coated with basement membrane, extracellular bundles of collagen, and axonal degeneration consistent with features of a nerve sheath neoplasm. This is the first report of primary, bilateral corneal nerve sheath sarcoma in a canine.  相似文献   

Glaucoma with Descemet's membrane detachment in five horses          下载免费PDF全文

Michala de Linde Henriksen  Noelle La Croix  David A. Wilkie  Mary Lassaline‐Utter  Karen R. Brantman  Gillian L. Beamer  Leandro B. C. Teixeira  Richard R. Dubielzig 《Veterinary ophthalmology》2017,20(3):273-279

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Outcome of phacoemulsification following corneal and lens laceration in cats and dogs (2000–2010)          下载免费PDF全文

Barbara K. Braus  Alexander Tichy  Heidi J. Featherstone  Peter W. Renwick  Michael Rhodes  Christine L. Heinrich 《Veterinary ophthalmology》2017,20(1):4-10

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A keratoprosthesis prototype for the dog     

Ingrid Allgoewer  Gillian J. McLellan†  ‡  Sunita Agarwal§ 《Veterinary ophthalmology》2010,13(1):47-52

Objective  To describe the technique for implantation of a novel keratoprosthesis (KP) prototype and evaluate its application for the treatment of corneal blindness in dogs.
Animals studied  Seven dogs, all of them being clinically blind before surgery as a result of severe corneal endothelial disease (5/7) or chronic superficial keratitis (2/7) that were unresponsive to prior therapy.
Procedures  A silicone KP was implanted unilaterally, just anterior to Descemet's membrane, after creating a stromal pocket by deep stromal lamellar dissection.
Results  Implantation of the KP was accomplished without complication in six of seven operated dogs. In the remaining case, an intra-operative complication (perforation of Descemet's membrane) was associated with extrusion of the KP 8 weeks postoperatively. All operated eyes regained limited vision after surgery. Three to six months after implantation purulent keratitis occurred in all five eyes with endothelial disease, necessitating surgical removal of the KP 6 months postoperatively in 5/7 eyes.
Conclusions  This KP prototype shows promise as a treatment for certain blinding corneal diseases. However, changes in the design of this KP, allowing improved stromal integration, will be necessary before its clinical application can be approved.  相似文献