黑龙江省鸡西地区奶牛子宫内膜炎病原菌分离鉴定及耐药性研究     

朱二勇  殷丽霞  曲立春  尹春花  孙学良  鞠连民 《畜牧与饲料科学》2014,(2):18-19

从黑龙江省鸡西地区部分奶牛场选取25头临床诊断为子宫内膜炎的患牛,并从这25头患牛体内分离得到39株细菌,其中大肠杆菌17株、葡萄球菌13株、链球菌5株、其他菌4株。耐药性试验表明,大肠杆菌、葡萄球菌和链球菌都对头孢曲松钠和头孢噻呋钠敏感,对庆大霉素比较敏感,对其他几种常用抗生素存在不同程度耐药性。  相似文献   

宫炎净中生物碱对子宫内膜炎家兔病理组织形态变化的影响     

贾书红  李效振  张东升  罗燕  孙跃博  谷新利 《中兽医医药杂志》2014,(6):8-11

为研究中药复方宫炎净中生物碱对子宫内膜炎家兔子宫组织病理形态变化的影响,本实验通过子宫灌注混合菌液建立子宫内膜炎家兔模型,观察家兔在造模前后的临床症状以及白细胞分类计数变化,确认造模成功后给予不同剂量的生物碱治疗,并在末次给药后,取各组家兔的子宫,观察其病理变化。结果显示,通过子宫灌注病原菌可以导致家兔采食量减少,精神状态差,体温升高,白细胞总数及中性粒细胞数显著增多（P〈0.05或P〈0.01）、淋巴细胞显著减少（P〈0.05）,成功建立子宫内膜炎家兔模型;通过观察家兔子宫组织变化,结果表明,宫炎净中生物碱有一定的活血化瘀、抗菌消炎作用,对子宫内膜炎家兔有较好的治疗作用。  相似文献   

The current status of antibiotic use in equine reproduction     

M. M. LeBlanc 《Equine Veterinary Education》2009,21(3):156-167

Antibiotics are infused into the uterine lumen, added to semen extenders and given systemically for infections of the reproductive tract of the mare and stallion. Evidence‐based guidelines for determining treatment length and route of administration are limited and use is frequently based on convenience or tradition. Current recommended antibiotic use for the treatment of bacterial and fungal endometritis, placentitis and metritis in the mare and genital infections of the stallion are presented. Antibiotic classes used for reproductive problems are also reviewed.  相似文献   

中西药结合治疗奶牛子宫内膜炎疗效观察     

傅军科  李洪涛  向春和  孙延鸣 《畜禽业》2008,(12)

选取81头患有不同类型子宫内膜炎的奶牛做临床治疗试验,试验组用中药复方"益孕液"+乳酸环丙沙星,对照组用土霉素,结果表明:复方"益孕液"+乳酸环丙沙星的有效率为91.3%,痊愈率为87.0%,与对照组相比,治疗的有效率无显著差异(P>0.05),受胎率显著高于对照组(P﹤0.05)。试验结果说明,复方"益孕液"结合乳酸环丙沙星治疗奶牛子宫内膜炎,具有抗菌消炎、诱导发情和提高受胎率的作用。  相似文献   

A review of fungal endometritis in the mare     

C. J. Scott 《Equine Veterinary Education》2020,32(8):444-448

Fungal endometritis is a relatively rare cause of infertility in the mare, accounting for only 1–5% of all cases of endometritis. However, it remains a challenge to the clinician due to difficulties in diagnosing and effectively treating affected mares, resulting in a high rate of recurrence and a guarded prognosis for ongoing fertility. Often occurring as an opportunistic infection, the most common causes of fungal endometritis in the mare are yeasts (Candida spp.) and moulds with septated hyphae (Aspergillus spp.). Early detection and identification of the causative agent are vital when choosing appropriate treatment as sensitivities to commonly used antifungals vary significantly. Assessing in vitro sensitivity for each isolate is accordingly recommended. Treatment of mares with fungal endometritis is multifaceted and includes; correction of any anatomical defects, uterine lavage and systemic and/or intrauterine infusion of antifungals. Concurrent bacterial infection is common so anticipation and subsequent treatment of bacterial endometritis is also often required.  相似文献   

Selected leukocyte subpopulations in peripheral blood and uterine washings in cows before and after intrauterine administration of cefapirin and methisoprinol     

Piotr Brodzki  Urszula Lisiecka  Adam Brodzki  Leszek Krakowski  Marek Szczubia&#x;  Roman D&#x;browski  Andrzej Junkuszew  Mariola Bochniarz 《Animal Science Journal》2020,91(1)

The aim of the study was to evaluate the selected lymphocyte subpopulations TCD4, TCD8, BCD21, BCD25, CD18, CD11b, and MHC II in blood and uterine flush of cows with endometritis, before and after intrauterine (i.u.) administration of cefapirin and methisoprinol. The research was carried out on 28 cows with clinical endometritis. Animals were divided into four groups, each composed of seven cows, depending on the i.u. preparation used: Group A, cefapirin; Group B, methisoprinol; Group C, cefapirin and methisoprinol simultaneously; and a control group—without medication. The study was performed using flow cytometry method. Summarizing the results of the research, i.u. infusion of cefapirin caused a weakening of the effector phase of the local uterine immune response; however, it enhanced leukocyte chemotaxis and antigen presentation. After i.u. administration of methisoprinol, the stimulation of specific uterine immunity mechanisms was mainly observed. The use of both mentioned preparations showed the strengthening of specific uterine immunological mechanisms presumably caused by methisoprinol, despite the inhibitory effect of the antibiotic. Intrauterine use of immunostimulatory substances can improve the effectiveness of the endometritis treatment in cows by improving specific local mechanisms of uterine immunity. As a consequence, it may enhance the effector function of immune competent cells and finally eliminate inflammation.  相似文献   

冬季某牛场奶牛子宫内膜炎与环境中主要致病菌分离鉴定、药敏试验及其相关性研究   总被引：1，自引：0，他引：1  

余致山  张爱荣  郭春燕  海岩  吴树清  张明月  杜山 《中国奶牛》2011,(16):35-38

对呼市地区某奶牛场的50头患子宫内膜炎奶牛及牛场环境进行采样,采集患牛子宫分泌物50份,环境样65份。并对采集的样本进行了病原菌分离鉴定,结果从50份奶牛子宫内膜炎样中分离出7种细菌共76株,从65份环境样分离出7种细菌共42株。对主要致病菌进行27种抗生素敏感试验,结果表明,从奶牛子宫内膜炎样和环境中分离的致病菌都对庆大霉素、氧氟沙星、环丙沙星和左氟沙星表现出高度敏感,而对青霉素G、新生霉素和氨曲南表现较强的耐药性。将从奶牛子宫内膜炎样本中分离的病原菌与相应环境中分离的细菌进行对比分析。发现两者存在一定的相关性。  相似文献   

规模化猪场母猪子宫内膜炎致病菌的分离鉴定   总被引：4，自引：0，他引：4  

叶健毅  赵学峰  兰邹然  陶家树 《畜牧兽医杂志》2011,30(1):5-7

从福建省南平市6个种猪场采集52头猪子宫内膜炎病猪子宫分泌物,分别进行致病菌分离鉴定,从52例子宫内膜炎患病母猪的活体病料中共分离细菌72株,检出率为150%。全部细菌分属为大肠杆菌、链球菌、葡萄球菌、沙门氏菌、绿脓杆菌、化脓棒状杆菌和克雷伯氏菌,分离到的细菌以大肠杆菌、链球菌和葡萄球菌占较大比例,它们分别占总检出菌株的43.0%、23.6%和16.7%。患猪中有61.5%的母猪为单一细菌感染;其它为细菌混合感染,混合感染比例,达到38.5%,其中以大肠杆菌造成的混合感染占比较高的比例,占总感染头数的28.8%。  相似文献   

盐酸环丙沙星在奶牛患子宫内膜炎时乳汁中的药动学及残留   总被引：3，自引：2，他引：3  

陶金忠  杨国林  赵兴绪  李剑勇  李世宏 《甘肃农业大学学报》2004,39(3):273-276

研究通过子宫内灌注盐酸环丙沙星,采用内标法以反相高效液相色谱法测定了4头患子宫内膜炎的奶牛乳汁中盐酸环丙沙星的药物浓度,用MCPKP房室分析程序处理乳中药物浓度-时间数据。研究表明,患牛子宫内给药的血样药时数据经MCPKP处理符合一级吸收一室开放模型。乳样中主要药动学参数为:Ka为0.091 25 h-1,tmax为19.17 h,Cmax为0.018 25 靏mL-1,AUC为1.032 mg(Lh)-1,T1/2Ka为8.25 h,T1/2K为24.64 h。弃奶期为4 d。  相似文献   

影响奶牛产后卵巢活动恢复的几个因素     

吴美文  杨培新 《浙江大学学报(农业与生命科学版)》1997,(5)

应用通讯奶样放射免疫分析法测定奶中孕酮含量，确定了１６４头次奶牛产后卵巢活动恢复的时间，并根据年产奶量、产犊季节和有无子宫内膜炎等进行分类统计．产后卵巢活动恢复延迟高产（１００００～７０００ｋｇ）奶牛中有５２．４％（１１／２１）；低产奶牛中占４１．３％（２６／６３）．秋季产犊的奶牛较早恢复卵巢活动，其次是冬季、春季和夏季．患子宫内膜炎的奶牛，有６６．７％产后卵巢活动恢复延迟，配种无效占５０．０％，情期受胎率为１４．３％．  相似文献