白血病抑制因子及其受体在月经周期猕猴输卵管内的表达   总被引：1，自引：0，他引：1  

岳占碰  李世杰  张学明  王洪斌  杨增明 《中国兽医学报》2005,25(4):385-387

应用免疫细胞化学方法对白血病抑制因子(LIF)、白血病抑制因子受体(LIFR)和gp130在月经周期猕猴输卵管内的表达进行了研究。结果表明，LIF、LIFR和gp130主要在输卵管上皮细胞内表达，而在固有层、肌层及泉膜内的表达量较少。LIF、LIFR和gp130在猕猴输卵管内的表达量随月经周期的不同而变化，在增殖中期到分泌中期的输卵管内表达量较高，而在增殖早期及分泌晚期输卵管内表达量较低。LIF及其受体在猕猴输卵管内的表达可能由卵巢分泌的类固醇激素所调控，LIF可能在猕猴排卵及早期胚胎发育过程中起重要的调节作用。  相似文献   

甘蓝型油菜胞质不育系130A的结实性研究     

徐洪志  曾川  廖淑梅  张大琼  陈吉光 《中国种业》2006,(11):29-31

在大田生产条件下对甘蓝型油菜胞质不育系130A自交和异交结实性研究结果表明：130A纱帐隔离自交结实，单株生产力7．9g，比可育株的23．4g低15．5g。在天然授粉情况下，130A的结实能力较强，单株生产力为24．3g，比可育株低3．7g。在大田开放授粉备件下，播种期之间130A异交结实形成的单株产量的差异很大，随着播种期推迟，单株产量呈下降趋势；130A自交结实随播种期波动变化，11月4日以后播种130A自交结果率为0，不育性表现稳定，前期130A不育性表现不稳定，上下波动。  相似文献   

Hydroxyethyl starch 130/0.4 compared with 0.9% NaCl administered to greyhounds with haemorrhagic shock     

Duana McBride  Anthea L. Raisis  Giselle Hosgood  Lisa Smart 《Veterinary anaesthesia and analgesia》2017,44(3):444-451

Objective

To determine the cardiovascular and acid-base effects of 6% hydroxyethyl starch (HES) 130/0.4 and 0.9% sodium chloride (NaCl) administered to anaesthetized greyhounds with haemorrhagic shock.

Study design

Prospective, experimental, complete randomized block design.

Animals

Twelve healthy adult greyhounds.

Methods

After 60 minutes of isoflurane anaesthesia, 48 mL kg^?1 of blood was removed to induce hypotension. Dogs were randomized to receive either 20 mL kg^?1 of HES 130/0.4 or 80 mL kg^?1 of 0.9% NaCl over 20 minutes. Haemoglobin, arterial and central venous blood gas and electrolytes, lactate, mean arterial pressure (MAP) and cardiac index were measured at: T0, 60 minutes after induction of anaesthesia, immediately prior to blood removal; T1, immediately after blood removal; T2, immediately after fluid administration; and T3, 40 minutes after fluid administration. Oxygen extraction ratio (O₂ER) was calculated at each sample time.

Results

O₂ER increased at T1 and decreased at T2 and T3, with no difference between the two groups. Dogs administered HES 130/0.4 had higher lactate at T2 [mean (95% confidence interval) 1.3 (0.8–1.9) mmol L^?1] than dogs administered 0.9% NaCl [0.8 (0.5–1.1) mmol L^?1]; p = 0.045. Dogs administered HES 130/0.4 had a higher MAP at T3 [88 (74–102) mmHg] than dogs administered 0.9% NaCl [69 (60–79) mmHg]; p = 0.019. Dogs administered 0.9% NaCl were more acidaemic at T2 and T3, including higher hydrogen ion, lower bicarbonate, lower base excess and higher chloride concentrations.

Conclusion

and clinical relevance The effect of 20 mL kg^?1 of HES 130/0.4 on shock, as measured by O₂ER, was no different than that of 80 mL kg^?1 of 0.9% NaCl in dogs under general anaesthesia. Acidaemia in the NaCl group is likely attributable to hyperchloraemic metabolic acidosis from the larger volume administered.  相似文献