Canine transmissible venereal tumour: a review          下载免费PDF全文

B. Ganguly  U. Das  A. K. Das 《Veterinary and comparative oncology》2016,14(1):1-12

Canine transmissible venereal tumour (CTVT) is a contagious venereal tumour of dogs, commonly observed in dogs that are in close contact with one another, or in stray and wild dogs that exhibit unrestrained sexual activity. CTVT represents a unique, naturally transmissible, contagious tumour, where the mutated tumour cell itself is the causative agent and perpetuates as a parasitic allograft in the host. Clinical history, signalment and cytological features are often obvious for establishing a diagnosis though biopsy and histological examination may be needed in atypical cases. Most cases are curable with three intravenous injections of vincristine sulphate at weekly intervals. The role of stray and wild dogs makes the disease difficult to control and necessitates sustained animal birth control in stray dogs along with prompt therapy of the affected dogs. This review captures the manifold developments in different areas embracing this fascinating tumour, including its biology, diagnosis and therapeutic alternatives.  相似文献   

The palliative efficacy of modified Mohs paste for controlling canine and feline malignant skin wounds     

Yasuhiro Fukuyama  Tetsushi Tezuka  Atsushi Kawabata  Takuya Maruo 《The Veterinary quarterly》2016,36(3):176-182

In veterinary medicine, the management of malignant skin wounds is highly challenging. We conducted a study on seven case animals (four dogs and three cats) which presented with malignant skin wounds. All seven animals had signs and symptoms which were controlled following treatment with a modified Mohs paste. Upon obtaining informed consent from their owners, the animals requiring management of malignant wounds were enrolled in this study. The modified Mohs paste was prepared by mixing zinc chloride, zinc oxide starch powder, glycerin, and distilled water. The modified Mohs paste was topically applied to and left to remain on the malignant wounds for one hour, under controlled conditions. Once the paste was removed, the wounds were irrigated with a solution of sterile saline. At the first examination, the wounds of each animal were observed for signs of exudate, malodor, and bleeding. In every case, visible improvement was observed immediately after the modified Mohs paste treatment. Specifically, the size of the malignant wounds, and the number of times the dressing gauze required changing, significantly decreased (p < 0.05 and p < 0.01, respectively). The open malignant skin wounds caused by mammary gland tumors disappeared in two cases. The Mohs paste has been shown to be a viable option for the palliative treatment in canine and feline malignant skin wound management.  相似文献   

Effect of the Glucagon‐like Peptide‐1 Analogue Exenatide Extended Release in Cats with Newly Diagnosed Diabetes Mellitus          下载免费PDF全文

A. Riederer  E. Zini  E. Salesov  F. Fracassi  I. Padrutt  K. Macha  T.M. Stöckle  T.A. Lutz  C.E. Reusch 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(1):92-100

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20份欧洲型黄瓜种质资源的半致死温度与耐热性研究     

左志梅  木万福  但忠  杨龙  杨长楷 《长江蔬菜》2016,(22)

为探讨不同欧洲型黄瓜种质资源对高温的适应性差异,为耐热种质资源筛选及耐热机理的深入研究提供理论和实践依据,以20份欧洲型黄瓜的叶片为材料,设置6个高温处理,以室温为对照,测定浸提液电导率值并计算相对电导率,通过拟合Logistic方程,计算半致死温度(LT50)。试验结果表明,随着温度升高,相对电导率呈"S"型曲线,且相对电导率与处理温度存在显著的直线相关关系,通过计算"S"型曲线拐点求得20份欧洲型黄瓜的半致死温度在45~51℃,其中33-2的半致死温度最高,达到50.09℃,37-1的半致死温度最低,为45.82℃。20份欧洲型黄瓜的耐高温能力由强到弱依次为33-275-232-233-111-231-209-236-276-136-137-210-135-276-211-143-235-175-132-137-1。因此,半致死温度可作为评价欧洲型黄瓜耐热性的一个可靠指标。  相似文献   

Cyclooxygenase (COX) inhibitors and the intestine   总被引：1，自引：0，他引：1  

Little D  Jones SL  Blikslager AT 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2007,21(3):367-377

Nonsteroidal anti-inflammatory drugs (NSAIDs) have long been used for the treatment of pain and inflammation because of their inhibitory effects on cyclooxygenase (COX). For almost as long as NSAIDs have been in use, multiple adverse effects have been noted. Assessment of many of these adverse effects have been complicated because of the discovery of multiple splice variants of the cox gene, and a greater array of COX inhibitors, especially the COX-2 selective inhibitors have become available. Some of these adverse effects cannot be readily explained by the effect of these drugs on COX. This has sparked a new field of investigation into the COX-independent effects of the COX inhibitors. The major noncyclooxygenase targets of the COX inhibitors of particular relevance to inflammation and the gastrointestinal tract are phosphatidylinositol 3'-kinase Akt signaling, uncoupling of oxidative phosphorylation, PPARgamma, nuclear factor KB, mitogen activated protein kinases, and heat shock proteins.  相似文献   

Carvedilol in dogs with dilated cardiomyopathy     

Oyama MA  Sisson DD  Prosek R  Bulmer BJ  Luethy MW  Fuentes VL 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2007,21(6):1272-1279

BACKGROUND: Dilated cardiomyopathy (DCM) is characterized by reduced systolic function, heightened sympathetic tone, and high morbidity and mortality. Little is known regarding the safety and efficacy of beta-blocker treatment in dogs with DCM. HYPOTHESIS: Carvedilol improves echocardiographic and neurohormonal variables in dogs with DCM over a 4-month treatment period. METHODS: Prospective, placebo-controlled, double-blinded randomized study. Dogs with DCM underwent echocardiography, ECG, thoracic radiographs, and neurohormonal profiling, followed by titration onto carvedilol (0.3 mg/kg q12h) or placebo over a 4-week period and subsequently received 3 months of therapy. Primary study endpoints included left ventricular volume and function. RESULTS: Sixteen dogs received carvedilol and 7 received placebo. At study end, 13 carvedilol dogs and 5 placebo dogs were alive. There was no difference in the mean percentage change in left ventricular volume at end-diastole (LVVd), left ventricular end-systolic volume (LVVs), and ejection fraction (EF) between treatment groups, suggesting that both groups experienced similar amounts of disease progression. Carvedilol treatment did not result in significant changes in neurohormonal activation, radiographic heart size, heart rate, or owner perceived quality-of-life. Baseline B-type natriuretic peptide (BNP) predicted dogs in the carvedilol-treated group that maintained or improved their EF over the study duration. CONCLUSIONS AND CLINICAL IMPORTANCE: Carvedilol administration did not improve echocardiographic or neurohormonal indicators of heart function. The lack of effect may be related to severity of disease, carvedilol dose, or brevity of follow-up time. Statistical power of the present study was adversely affected by a high fatality rate in study dogs and small sample size.  相似文献   

Tsetse control in cattle from pyrethroid footbaths     

Bouyer J  Stachurski F  Kaboré I  Bauer B  Lancelot R 《Preventive veterinary medicine》2007,78(3-4):223-238

In Burkina Faso, we assessed the efficacy of treating cattle with a footbath containing aqueous formulations of pyrethroids to control two tsetse-fly species, Glossina tachinoides Westwood, 1850 (Diptera, Glossinidae) and Glossina palpalis gambiensis Vanderplank 1949. Legs were the most targeted parts of the body for tsetse-fly blood meals: 81% (95% CI: 73, 89) for G. tachinoides and 88% (81, 95) for G. palpalis.

The in-stable efficacy of footbath treatments was compared with manual full spraying with a 0.005% alphacypermethrin (Dominex, FMC, Philadelphia, USA) formulation (250 mL versus 2 L). The proportions of knocked-down flies were the same with footbath and full spray but the latter was more protective against fly bites. In field use, the efficacy of both methods should be similar given the recommended treatment frequency: 3 days for footbath versus 7 days for full spray.

Among 96 cattle drinking at the same water point in Dafinso (Burkina Faso), 68 (71%) were treated with a footbath containing a 0.005% deltamethrin formulation (Vectocid, CEVA SA, Libourne, France). We observed the effect of this live-bait technique on the one hand on released cohorts of reared, irradiated flies, and on the other hand on wild tsetse flies. In both cases, the footbath treatment was associated with a reduction of the apparent fly density probably related to an increased mortality.  相似文献   

Quantification of flight times of aerial treatments targeting invasive species: the interplay of helicopter or drone with bait-delivery systems,flight speed and bait form     

Benjamin D. Hoffmann  Adam Tessmann  Greg Quinn  Faye Lawton 《Pest management science》2023,79(6):2050-2055

BACKGROUND

Aerial treatments for invasive species management are now common, but we are unaware of any work published in the scientific literature quantifying how the interplay of numerous factors affects flight time and therefore operational costs. Here, we analyse aerial treatment data collected from two ant-eradication programmes, quantifying how the relationships between flight time and area are influenced by numerous aircraft/delivery system/bait/flight speed combinations.

RESULTS

For bait dispersal by helicopters, and when swath widths are equivalent, side-mounted Isolair was significantly more efficient than the simultaneous use of two underslung buckets, and use of two buckets was slightly but not significantly more efficient than one bucket. In this scenario, delivery by Isolair was, on average, 39.8% and 31.5% more efficient than the use of one or two buckets, respectively. However, when the swath width used with Isolair was halved to 10 m and flight speed was increased slightly, flight time was significantly greater compared to the other configurations. For bait dispersed by drone, flights conducted using an upgraded Flight Management System (FMS) and greater flight speed but smaller swath width were significantly more efficient than flights using the older FMS and lower flight speed. Over 10 and 50 ha the helicopter was 2.87 and 4.82 times more time efficient than the drone.

CONCLUSION

We encourage practitioners to publish data from their aerial treatments, and to try new methods, to accelerate improvements in efficiency and reduce the costs of aerial treatments. © 2023 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.  相似文献   

翅片管加热器换热过程综合能量特性研究     

高青  李欣欣 《农业机械学报》1997,28(4):59-62

在研究翅片管加热器传热性能及流阻性能的基础上，依据热力学理论，利用不可逆过程Ｙｏｎｇ分析，着重分析管速换热过程的能量特性，将换热过程的传热性能与流阻性能有机地结合提出便于工程实际应用的能量特性分析准则函数。依此探讨管束换热过程特征参数对综合能量利用性能的影响，指导翅片管加热器能量的高效利用，并与光管加热器进行了比较分析。  相似文献   

春小麦耐热性的筛选方法与指标   总被引：4，自引：0，他引：4  

徐如强  孙其信 《华北农学报》1997,12(3):22-29

利用５１份春小麦材料对３种耐热性方法进行了研究评价。供试材料在田间通过晚播计算各基因型的粒重感热指数（Ｓｅ）或于籽粒浆期用塑料简棚进行遮盖处理并计算千料重感热指数（Ｓｇ）评价其耐热性，而在室骨采用膜热稳定性测定方法，以相对热损伤率（ＲＩ％）大小评价基因型的耐热性。相关分析表明：Ｓｅ在年际间和年份内的相关系数均呈极显著高度正相关，从而具有较好的重演性，而ＲＩ％与Ｓｇ呈显著正相关说明基因型的热稳定性大  相似文献