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PIateIet-activatingfact0r(PAFf1-O-aIkyI-2-acetyl-sn-glycer0-3-ph0sph0ch0Iine)wasdiscoveredasachemicaImediat0r,reIeasedfromsensitizedbas0-phiIs(Benvenisteetal1972),thatcausedpIateIetaggregati0n.SubsequentstudiesdemonstratedthatPAFwasproduceduponappropriatestimulation0favariety0fhumancells,includingneutrophils,e0sino-phils,mon0cytes,andend0thelialcells,andthisp0-tentlipidmediatorisinv0IvedinanumberOftheal-IergicandinfIammatoryresp0nses(Hanahan1986;BraquetetaI1987;WalIace1989IPresc0tte… 相似文献
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EarlypregnanCyf8Ctor(EPF)isoneoftheearlieStbiochemicalindicatorsofpregnancy(Mortonetal.,1974).IthasbeendeteCtedwithinhoursoff6rtilizationbeinginducedbythereleaseofplateletaCtivatingfaCtor(PAF)fromthef6rtilizationovum,andpresentforstleastthefieSt-two-thiEdsofpregnanCy,continueddeteCtionbeingdependentuponthepresenceofaviableembryoorf6tus(Orozcoetal.,1986;Mortonetal.,1987).ThismoStinterestingaCtivitywithpotentialapplicationsinearlypregnancyteSting,formonitoringf6talwell-beingandintheStud… 相似文献
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