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The ethyl acetate, acetone and methanol extracts of Wrightia tinctoria bark showed antinociceptive activity on acetic acid-induced writhing test in mice, their effects being comparable to that of acetylsalicylic acid. 相似文献
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Y. S. Sodhi A. K. Pradhan J. K. Verma N. Arumugam A. Mukhopadhyay D. Pental 《Plant Breeding》1994,112(3):223-227
Eighteen genotypes of Brassica napus were crossed to a cytoplasmic male sterile (CMS) line of B. napus BO 15 carrying B. tournefortii cytoplasm (‘tour’ cytoplasm). Fourteen genotypes were found to be stable maintainers of the ‘tour’ CMS. Of the remaining four genotypes, GSL-1 and ‘Asahi-natane’ were found to be heterozygous and ‘Mangun’ and ‘Yudal’ were homozygous for the restorer gene. Analysis of the F1 and F2 progenies of (CMS) BO 15 בMangun’ and (CMS) BO 15 בYudal’ showed that fertility restoration is controlled by a single dominant gene. The availability of a number of stable maintainer lines and the simple inheritance pattern of fertility restorer gene makes ‘tour’ CMS a useful system for hybrid seed production in rapeseed. 相似文献
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The present study was aimed to investigate the possible interaction of the standardized extract of Acorus calamus (AC) with Cytochrome P450 enzyme, quantitative determination of the α-asarone in the AC rhizome was performed by RP-HPLC method. In vitro interaction of the plant extract was evaluated by CYP450-carbon monoxide complex (CYP450-CO) assay. Effect on individual isoforms such as CYP3A4 and CYP2D6 isozymes were analyzed through fluorescence product formation and respective IC50 values were determined. CYP450-CO assay showed moderate interaction potential. Extract showed higher IC50 values (46.84 ± 1.83-32.99 ± 2.21 μg/ml) comparing to the standard inhibitors and lower IC50 value than α-asarone (65.16 ± 2.37-42.15 ± 2.45 μg/ml). 相似文献
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Govindasamy Rajakumar Abdul Abdul Rahuman Kanayairam Velayutham Jeyaraman Ramyadevi Kadarkaraithangam Jeyasubramanian Arumugam Marikani Gandhi Elango Chinnaperumal Kamaraj Thirunavukkarasu Santhoshkumar Sampath Marimuthu Abdul Abduz Zahir Asokan Bagavan Chidambaram Jayaseelan Arivarasan Vishnu Kirthi Moorthy Iyappan Chinnadurai Siva 《Veterinary parasitology》2013,191(3-4):332-339
The present study was on assessment of the anti-parasitic activities of nickel nanoparticles (Ni NPs) against the larvae of cattle ticks Rhipicephalus (Boophilus) microplus and Hyalomma anatolicum (a.) anatolicum (Acari: Ixodidae), fourth instar larvae of Anopheles subpictus, Culex quinquefasciatus and Culex gelidus (Diptera: Culicidae). The metallic Ni NPs were synthesized by polyol process from Ni-hydrazine as precursor and Tween 80 as both the medium and the stabilizing reagent. The synthesized Ni NPs were characterized by Fourier transform infrared (FTIR) spectroscopy analysis which indicated the presence of Ni NPs. Synthesized Ni NPs showed the X-ray diffraction (XRD) peaks at 42.76°, 53.40°, and 76.44°, identified as 1 1 1, 2 2 0, and 2 0 0 reflections, respectively. Scanning electron microscopy (SEM) analysis of the synthesized Ni NPs clearly showed that the Ni NPs were spherical in shape with an average size of 150 nm. The Ni NPs showed maximum activity against the larvae of R. (B.) microplus, H. a. anatolicum, A. subpictus, C. quinquefasciatus and C. gelidus with LC50 values of 10.17, 10.81, 4.93, 5.56 and 4.94 mg/L; r2 values of 0.990, 0.993, 0.992, 0.950 and 0.988 and the efficacy of Ni-hydrazine complexes showed the LC50 values of 20.35, 22.72, 8.29, 9.69 and 7.83 mg/L; r2 values of 0.988, 0.986, 0.989, 0.944 and 0.978, respectively. The findings revealed that synthesized Ni NPs possess excellent larvicidal parasitic activity. To the best of our knowledge, this is the first report on larvicidal activity of blood feeding parasites using synthesized Ni NPs. 相似文献
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Mohd. Iqbal Yatoo Oveas Raffiq Parray Shah Tauseef Bashir Muheet Riyaz Ahmed Bhat Arumugam Gopalakrishnan 《The Veterinary quarterly》2019,39(1):1-25
Contagious caprine pleuropneumonia (CCPP) is a serious disease of goats, occasionally sheep and wild ruminants, caused by Mycoplasma capricolum subspecies capripneumoniae (Mccp). The disease is characterized by severe serofibrinous pleuropneumonia, very high morbidity (～100%), and mortality (80–100%). CCPP affects goats in more than 40 countries of the world thereby posing a serious threat to goat farming around the globe. The characteristic clinical signs of CCPP are severe respiratory distress associated with sero-mucoid nasal discharge, coughing, dyspnea, pyrexia, pleurodynia, and general malaise. In later stages, severe lobar fibrinous pleuropneumonia, profuse fluid accumulation in pleural cavity, severe congestion of lungs and adhesion formation is observed. Mycoplasmal antigen interactions with host immune system and its role in CCPP pathogenesis are not clearly understood. CCPP is not a zoonotic disease. Diagnosis has overcome cumbersome and lengthy conventional tests involving culture, isolation, and identification by advanced serological (LAT, cELISA) or gene-based amplification of DNA (PCR, RFLP, and hybridization) and sequencing. The latex agglutination test (LAT) is rapid, simple, and better test for field and real-time diagnosis applicable to whole blood or serum and is more sensitive than the CFT and easier than the cELISA. Moreover, the studies on antibiotic sensitivity and exploration of novel antibiotics (fluoroquinolones, macrolides) can help in better therapeutic management besides preventing menace of antibiotic resistance. Re-visiting conventional prophylactic measures focussing on developing novel strain-based or recombinant vaccines using specific antigens (capsular or cellular) should be the most important strategy for controlling the disease worldwide. 相似文献
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Kadarkarai Murugan Kandasamy Kalimuthu Palanisamy Mahesh Kumar Jiang-Shiou Hwang Marcello Nicoletti 《Phytoparasitica》2013,41(3):307-316
The efficacy of copepod Mesocyclops aspericornis (Daday) combined with the larvicide Bacillus sphaericus (Bs) and a plant extract of Plectranthus amboinicus leaf abstract (PALE), used jointly and singly, was studied against Aedes aegypti in the laboratory. P. amboinicus leaf extract of 20, 40, 60, 80 and 100 ppm caused significant mortality against Ae. aegypti larvae. The LC50 and LC90 values for I to IV instars larvae and pupae were 26.12, 35.36, 45.76, 52.32 and 63.82 ppm, respectively. The LC90 values for I to IV instars larvae and pupae were 82.53, 92.65, 108.06, 119.47 and 131.71 ppm, respectively. Under laboratory conditions, copepods treatment produced 7.9% predatory efficiency against 1st instar larvae of Ae. aegypti, at a copepod:larvae ratio of 1:10. When copepod treatment was combined with PALE this was increased to 8.7. The treatment of copepods combined with Bs and PALE yielded a better and more sustainable result (9.6%) than the agents used individually. This predation efficiency may be caused by detrimental effects of the P. amboinicus active principle compound (carvacrol) on the mosquito larvae. Our results suggest that the combined application of microbial insecticide (Bs), copepods and P. amboinicus leaf extract may be used to control Aedes populations. 相似文献
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Amarchand Chordia Murugan Jibu Thomas Raj Kumar Rajagopal AbulKalamAzad Mandal 《Journal of Crop Science and Biotechnology》2012,15(1):53-57
Effects of exogenous application of ascorbic acid on physiological and metabolic changes in tea were investigated in the present
study. The highest improvement in yield was evident in response to regular application (a day after every harvest) of ascorbic
acid at 600 ppm followed by 400 ppm. Foliar application of ascorbic acid (600 ppm) at regular intervals enhanced chlorophyll
a and b contents besides a significant increase in total polyphenols and catechins when compared to the untreated control. Exogenous
application of ascorbic acid at alternate harvesting rounds increased the activity of polyphenol oxidase whereas ascorbate
peroxidase remained unchanged. An increase in phenylalanine ammonia lyase activity was noticed with foliar application of
ascorbic acid irrespective of its concentrations. Theaflavins and thearubigins of made tea showed an increase when ascorbic
acid was applied with 400 and 600 ppm at alternate intervals. The scores of brewed tea liquor characteristics, viz. infusion,
color, strength, and briskness were higher even at the lower concentration of ascorbic acid treatment. Results suggest that
foliar application of ascorbic acid (400 ppm) proved to be a useful measure to improve the yield, physiological attributes,
and antioxidant properties of tea. 相似文献
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Effect of Feronia limonia on mosquito larvae. 总被引：8，自引：0，他引：8
Bioassay guided fractionation of the acetone extract of Feronia limonia dried leaves afforded a potent mosquito larvicide, identified as n-hexadecanoic acid and found to be effective against fourth instar larvae of Culex quinquefasciatus, Anopheles stephensi and Aedes aegypti, with LC50 of 129.24, 79.58 and 57.23 ppm, respectively. 相似文献